A Meta-Analysis of the Current State of Evidence of the Incredible Years Teacher-Classroom Management Program

This meta-analysis evaluated the current state of evidence and identified potential treatment moderators of the Incredible Years Teacher Classroom Management (IYTCM) program used to reduce externalizing and internalizing behaviors in school-aged children. Inclusion criteria involved published studies between 1984–2018 and examining the effects of IYTCM as a standalone program on teacher and/or child behavioral outcomes. We identified and narratively summarized potential moderators, which included the severity of child behavior, dosage, study design, and reporting methods. Overall, effect sizes revealed IYTCM had moderate positive effects on teachers and small positive effects on children. Narrative summaries indicated larger effect sizes in higher dosage studies and higher risk children. The results align with previous systematic reviews on the Incredible Years Parent Training (IYPT) program but this is the first study to look at the teacher training program. Overall, IYTCM seems to be an effective intervention; however, what components of this program work best, for whom, and under what conditions require further empirical investigation.

Experimental study on silver nanoparticles: synthesis, photo-degradation and analysis

The aim of present study was waste water treatment via advanced oxidation process (AOP). Wet chemical precipitation method was used to prepare silver nanoparticles (Ag NPs). The Ag NPs were employed for photo catalytic degradation of Congo red (CR) dye in aqueous medium. The scanning electron microscopy (SEM) investigation shows agglomerated form of Ag NPs. The average sizes of agglomerations are below 600 nm. Energy dispersive X-rays spectroscopy (EDX) and ultraviolet light visible spectroscopy (UV/Vis) also established the formation of Ag NPs. The photo-degradation study reveals that Ag NPs degraded by 73% of CR dye in 480 min. Catalytic dosage study shows the dye degradation was increased vice versa as increased the amount of Ag NPs and then almost level off after 0.025 g of catalyst. In pH study it was observed that degradation of CR dye increased as pH increased. The recovered catalyst study also significantly degraded the CR dye.

Abstract W MP94: Neuroprotective Effect of Isosteviol Sodium on Focal Cerebral Ischemia in Rats

Background & Objective: Isosteviol is a molecule derived from Steviaside which has been used as sweetener worldwide. In this study, sodium salt of isosteviol (STVNA) was given i.v. in rats hours after the transient or permanent middle cerebral artery occlusion (tMCAO or pMCAO) to investigate its therapeutic neuroprotective effects. Methods: In male Sprague-Dawley rats 2 hours tMCAO with reperfusion or pMCAO was induced and ischemia were confirmed by a laser doppler flowmetry simultaneously. In dosage study, animals were divided into 6 groups: sham, vehicle, or treatment with STVNA at dosage of 1, 5, 10mg•kg-1 or Edaravone 1 hour before the onset of reperfusion. In therapeutic time window study, animals were divided into 5 groups: sham, vehicle, STVNA (10mg•kg-1) at 0, 2 or 4 hours after reperfusion. In pMCAO study, animals were divided into 5 groups: sham, vehicle or STVNA (10mg•kg-1) at 1, 2 or 4 hours after ischemia. Rats were assessed for neurobehavioral deficits after 24 hours and sacrificed for infarct volume quantitation and histology evaluation. Proteomic analysis of the penumbra area in some rats used a Snaps G2x MS-TOF system. Results: In dosage study, the infarct volume of STVNA 10mg•kg-1 group was significantly less compared either with the vehicle group (22±2% vs 41±5%, p< 0.01) or with the Edaravone group (22±2% vs 30±3%, p< 0.05 ). The therapeutic window study shows that STVNA treated at 4h after reperfusion still has significant effects than vehicle group (32±4% vs 41±5%, p<0.05). In pMCAO study, the infarct volume of STVNA at 4h still decreased comparing the vehicle group(29±5% vs 50±6%, p< 0.05).In all STVNA treated groups the neurobehavioral deficits were significantly improved, and there are more restored NeuN-labeled neurons and alleviated TUNEL positive cells in penumbra in comparing with the vehicle group. Proteomic analysis indicates that proteins involved in various inflammations associated signal pathways were dramatically increased by tMCAO, and then were greatly reduced after treated with STVNA. Conclusions: STVNA exhibited remarkable neuroprotective effects when administered 4 hours after pMCAO or 4 hours after reperfusion of tMCAO. Since STVNA has low systemic toxicity, it may be a better alternative for the treatment of stroke.

Experiment Study of Influence Factors on High-Temperature Stability of Closely Gap-Graded Bituminous Mixture

Rutting in asphalt pavements continues to create problems for pavement. The aim of this study was to analyze the influence of different gradation composition, asphalt dosage, temperature and dosage of anti-rutting agent on high-temperature stability of cosely gap-graded bituminous mixture. To achieve this objective, 171 different rutting specimens using different mix parameters were analyzed for their the high-temperature stability. The mix parameters include: three types of aggregate gradation, five types of asphalt dosage, four types of temperature and five types of anti-rutting agent dosage. Study results indicate that adding proper content of coarse aggregate can play occluding and wedging role in aggregate mixture. The optimal bituminous dosage in rutting test are lower 0.1%~0.3% than that in Marshell test. At 65°C, the high-temperature stability of the cosely gap-graded bituminous mixture is not able to meet the requirement of standards. The optimal dosage of anti-rutting agent are equal to 0.3% in case of no increasing bituminous dosage.