Can Surgeons Use Parathyroid Hormone Levels as Predictive Value in Parathyroid Adenomas?

Aim: Previous studies using different methods for PTH measurement have found a mild to moderate correlation between iPTH and gland weight. The aim of this study was to describe the relationship between parathyroid hormone and parathyroid adenoma volume, in patients with parathyroid adenomas as predictive value. Material and Methods: The multicenteric study was prepared by retrospectively collecting data from 244 patients with parathyroid adenoma who underwent parathyroidectomy and followed up between 2010 and 2020. Results: Two hundred forty and four (female/male = 203/41) patients with a mean age of 51.41 [min-max: 17 to 88] years. The mean iPTH concentrations preoperatively were 584.27 ng/L [min-max: 18.9 to 5011ng/L]. The mean diameter of adenoma of patients was 2,865 mm3 [min-max: 0.119 to 42.3 mm3]. After parathyroidectomy, PTH values were reevaluated and found as 47.2 ng/L [min-max: 0.2 to 903 ng/L]. In the patients with large parathyroid adenoma volume, preoperative PTH hormone values were statistically significantly higher (p=0.001). Conclusion: Our current study found a positive association between baseline iPTH levels and adenoma weight. These results suggest that serum iPTH level may be useful in predicting parathyroid adenoma volume.

Heterotopic Salivary Gland Tissue in the Larynx

Heterotopic Salivary Gland Tissue (HSGT) of the larynx is an extremely rare pathology, with only 8 cases reported in English literature. We are reporting 2 cases of HSGT in the larynx which we encountered in our practice. The first one is a unique presentation of a 45 year old female with HSGT in bilateral false vocal cords. While the second case is 50-year-old male patient with HSGT in the left false vocal cord and subglottic region. With these 2 cases, we would be discussing about the clinical presentation of this rare anomaly and add to the literature.

Effectiveness of 3 Months of Sublingual Immunotherapy Treatment in Patients with Allergic Rhinitis

Introduction: Allergic Rhinitis is one of the most frequent diseases that affect the global population and impairs quality of life. The initial management includes pharmacological treatment and the patients who are refractory to pharmacological treatment are then referred for immunotherapy. SLIT has been widely used for treatment of allergic rhinitis and has proven its clinical efficacy.Objective: To compare the function of mucociliary layer of the nasal cavity by assessing its clearance of the saccharin molecule as well as to compare the skin sensitivity erythema before and after treatment with sublingual immunotherapy in patient with allergic rhinitis.Methods: 50 patients were included in the quasi experimental study according to inclusion criteria and the finding were noted before the treatment with SLIT and then after 3 months post treatment.Results: The analysis showed significant difference p-value Results: The analysis showed significant difference (p-value <0.01) in the function of mucociliary clearance and skin sensitivity erythema after treatment.Conclusion: Sublingual immunotherapy shots administered to allergic rhinitis patients for 3 months is associated with significant improvement in their mucociliary layer function and reduce signs and symptoms of allergic reactions.