This introductory chapter outlines Locke’s innovative contributions to debates about persons and personal identity. His view builds, first, on moral and legal conceptions of a person, which can be found in natural law theory, second, on metaphysical debates about individuation and identity, and, third, on metaphysical and religious debates about the afterlife and the state of the soul between death and resurrection. The chapter shows that he not only builds on these debates, but also how he systematically brings the different debates together in new ways and how his distinction between the ideas of person, man, and substance makes it possible to advance the debates of his day. Moreover, this chapter presents the aims and scope of the book and offers a summary of the subsequent chapters.