Phosphodiesterases as Drug Targets - Handbook of Experimental Pharmacology
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Published By Springer Berlin Heidelberg

9783642179686, 9783642179693

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Phosphodiesterases in the Central Nervous System: Implications in Mood and Cognitive Disorders

Phosphodiesterases as Drug Targets - Handbook of Experimental Pharmacology ◽

10.1007/978-3-642-17969-3_19 ◽

2011 ◽

pp. 447-485 ◽

Author(s):

Ying Xu ◽

Han-Ting Zhang ◽

James M. O’Donnell

Keyword(s):

Central Nervous System ◽

Nervous System ◽

Cognitive Disorders ◽

The Central Nervous System

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A Fission Yeast-Based Platform for Phosphodiesterase Inhibitor HTSs and Analyses of Phosphodiesterase Activity

Phosphodiesterases as Drug Targets - Handbook of Experimental Pharmacology ◽

10.1007/978-3-642-17969-3_5 ◽

2011 ◽

pp. 135-149 ◽

Author(s):

Didem Demirbas ◽

Ozge Ceyhan ◽

Arlene R. Wyman ◽

Charles S. Hoffman

Keyword(s):

Fission Yeast ◽

Phosphodiesterase Inhibitor ◽

Phosphodiesterase Activity

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Evaluation of the Therapeutic Utility of Phosphodiesterase 5A Inhibition in the mdx Mouse Model of Duchenne Muscular Dystrophy

Phosphodiesterases as Drug Targets - Handbook of Experimental Pharmacology ◽

10.1007/978-3-642-17969-3_14 ◽

2011 ◽

pp. 323-344 ◽

Author(s):

Justin M. Percival ◽

Candace M. Adamo ◽

Joseph A. Beavo ◽

Stanley C. Froehner

Keyword(s):

Duchenne Muscular Dystrophy ◽

Muscular Dystrophy ◽

Mouse Model ◽

Mdx Mouse ◽

Therapeutic Utility

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Therapeutic Potential of Phosphodiesterase Inhibitors in Parasitic Diseases

Phosphodiesterases as Drug Targets - Handbook of Experimental Pharmacology ◽

10.1007/978-3-642-17969-3_20 ◽

2011 ◽

pp. 487-510 ◽

Author(s):

Yasmin Shakur ◽

Harry P. de Koning ◽

Hengming Ke ◽

Junichi Kambayashi ◽

Thomas Seebeck

Keyword(s):

Therapeutic Potential ◽

Phosphodiesterase Inhibitors ◽

Parasitic Diseases

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Pharmacology, Clinical Efficacy, and Tolerability of Phosphodiesterase-4 Inhibitors: Impact of Human Pharmacokinetics

Phosphodiesterases as Drug Targets - Handbook of Experimental Pharmacology ◽

10.1007/978-3-642-17969-3_3 ◽

2011 ◽

pp. 85-119 ◽

Author(s):

Hermann Tenor ◽

Armin Hatzelmann ◽

Rolf Beume ◽

Gezim Lahu ◽

Karl Zech ◽

...

Keyword(s):

Clinical Efficacy ◽

Human Pharmacokinetics ◽

Phosphodiesterase 4 ◽

Phosphodiesterase 4 Inhibitors

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Role of Phosphodiesterases in Adult-Onset Pulmonary Arterial Hypertension

Phosphodiesterases as Drug Targets - Handbook of Experimental Pharmacology ◽

10.1007/978-3-642-17969-3_12 ◽

2011 ◽

pp. 279-305 ◽

Author(s):

F. Murray ◽

M. R. MacLean ◽

P. A. Insel

Keyword(s):

Pulmonary Arterial Hypertension ◽

Arterial Hypertension ◽

Adult Onset ◽

Pulmonary Arterial

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Structural Insight into the Substrate Specificity of Phosphodiesterases

Phosphodiesterases as Drug Targets - Handbook of Experimental Pharmacology ◽

10.1007/978-3-642-17969-3_4 ◽

2011 ◽

pp. 121-134 ◽

Author(s):

Hengming Ke ◽

Huanchen Wang ◽

Mengchun Ye

Keyword(s):

Substrate Specificity ◽

Structural Insight ◽

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Phosphodiesterase Inhibitors in the Treatment of Inflammatory Diseases

Phosphodiesterases as Drug Targets - Handbook of Experimental Pharmacology ◽

10.1007/978-3-642-17969-3_17 ◽

2011 ◽

pp. 391-414 ◽

Author(s):

C. P. Page ◽

D. Spina

Keyword(s):

Inflammatory Diseases ◽

Phosphodiesterase Inhibitors

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Phosphodiesterase Inhibitors: Factors That Influence Potency, Selectivity, and Action

Phosphodiesterases as Drug Targets - Handbook of Experimental Pharmacology ◽

10.1007/978-3-642-17969-3_2 ◽

2011 ◽

pp. 47-84 ◽

Author(s):

Sharron H. Francis ◽

Miles D. Houslay ◽

Marco Conti

Keyword(s):

Phosphodiesterase Inhibitors

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Harnessing the Clinical Efficacy of Phosphodiesterase 4 Inhibitors in Inflammatory Lung Diseases: Dual-Selective Phosphodiesterase Inhibitors and Novel Combination Therapies

Phosphodiesterases as Drug Targets - Handbook of Experimental Pharmacology ◽

10.1007/978-3-642-17969-3_18 ◽

2011 ◽

pp. 415-446 ◽

Author(s):

Mark A. Giembycz ◽

Robert Newton

Keyword(s):

Clinical Efficacy ◽

Lung Diseases ◽

Phosphodiesterase Inhibitors ◽

Combination Therapies ◽

Phosphodiesterase 4 ◽

Phosphodiesterase 4 Inhibitors

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