Patch testing with potassium dichromate in different vehicles

1969 ◽  
Vol 99 (6) ◽  
pp. 697-700 ◽  
Author(s):  
E. Skog
Open Medicine ◽  
2012 ◽  
Vol 7 (1) ◽  
pp. 124-128
Author(s):  
Sonja Prcic ◽  
Aleksandra Matic ◽  
Milan Matic ◽  
Aleksandra Petrovic ◽  
Verica Djuran ◽  
...  

AbstractTemporary henna tattoos have recently become increasingly popular, especially among teenagers. Combining henna with other colouring agents such as para-phenylenediamine (PPD) may increase its potential for contact sensitization, cross-reaction to related compounds, as well as life-long allergy. Several cases of contact dermatitis from temporary tattoos with black henna have been reported in the literature. We present our experiences with 4 pediatric cases of allergic contact dermatitis induced by henna tattooing and give a brief review of the literature. The agent responsible for contact allergy was proven to be PPD in 3 patients, and in one patch testing revealed positive reactions to PPD and benzocaine, as well as to wool alcohols, nickel sulphate and potassium dichromate, to previously used hair dye—all being of clinical relevance.


2022 ◽  
Vol 1 ◽  
pp. 17-20
Author(s):  
Trupti Desale ◽  
Abhishek De ◽  
S. K. Shahriar Ahmed ◽  
Aarti Sarda ◽  
Kiran Godse ◽  
...  

Objectives: Chronic spontaneous urticaria (CSU) is defined as short lived (< 24h) wheals occurring spontaneously without any triggering factors, daily or almost daily for at least 6 weeks. Though CSU is mainly a Type 1 hypersensitivity reaction, earlier studies suggested contact allergy may have some role to play an important role in the etiopathogenesis of CSU. The objective of the study is to find out the relevance of patch test in the etiopathogenesis of and its correlation with serum IgE level. Materials and Methods: Thirty-one patients of CSU were thoroughly evaluated for clinical and laboratory parameters. We conducted patch testing with Indian Standard Series (ISS) in all of them and tried to find out the relevance of every positive reaction. Relevant positive cases were asked to avoid exposure for 2 months and were maintained only in breakthrough antihistamines. Furthermore, correlation of positive patch test reaction with high IgE and eosinophil count were studied. Results: Seventeen (55%) cases came positive for patch test. Potassium dichromate, lanolin, benzocaine, and fragrance mix were the most common offenders. Patients with very high IgE count had patch test positivity with multiple allergens. Seven of the fifteen patients who had relevant positive patch results could be followed up to remission; three were lost to follow-up. Conclusion: Patch test with ISS may give important clue to in a subset of patients of CSU and thus may be considered an important part of routine investigations of CSU.


1998 ◽  
Vol 9 (2) ◽  
pp. 92-95
Author(s):  
Meredith Klein Kosann ◽  
Ronald R. Brancaccio ◽  
Jerome L. Shupack ◽  
Andrew G. Franks ◽  
David E. Cohen

2016 ◽  
Vol 14 (1) ◽  
pp. 14-17
Author(s):  
S. Bhattarai ◽  
A. Rijal ◽  
S. Agrawal

Introduction: Allergic contact dermatitis in Nepal is not an uncommon disorder. Patch testing is a well established method of diagnosing allergic contact dermatitis. Patients with contact dermatitis are well known to have impaired quality of life which often leads to frequent dermatological consultations.Objective: Lack of data from Nepal has prompted us to undertake this study with the aims to know the frequency of allergic contact dermatitis and the commonest contact allergens among the patients with Hand eczema attending the out-patient department of dermatology, B.P. Koirala Institute of Health Sciences and Kathmandu Medical College Teaching Hospital.Material and Methods: A total of 256 patients were included in the study. Out of them 195 with hand eczema agreed to participate and undergo patch testing. The antigens used included the Indian standard series of patch test allergens approved by Contact and Occupational Dermatoses Forum of India.Results: Hundred and ten cases (56.4%) were patch test positive (PTP) at 48 as well as 96 hours to at least one allergen. PTP was seen more commonly in females. The most common allergen in females was nickel sulphate followed by cobalt chloride, gentamicin and mercapto mix while males were positive to potassium dichromate, followed by epoxy resin, fragrance mix and nickel sulphate.Conclusion: Patch testing has proved a useful tool for the detection of allergic contact dermatitis and for identification of contact allergens. When positive reactions correlate with environmental exposure the test usually assists the physician in establishing the cause of dermatitis, hence treating the patients and improving their quality of life.Nepal Journal of Dermatology, Venereology & Leprology, Vol.14(1) 2016, pp.14-17


2019 ◽  
Vol 70 (4) ◽  
pp. 1337-2341 ◽  
Author(s):  
Maria-Magdalena Constantin ◽  
Stefana Bucur ◽  
Clara Matei ◽  
Iuliana Elena Nita ◽  
Traian Constantin

In Romania, data on patch testing are lacking and the significance and applicability of the European baseline series (EBS) needs to be evaluated. The aim of the study was to examine the prevalence of contact allergy to the EBS and to determine the most common post-test sensitization occurred in the population of patients with suspected allergic contact dermatitis in Romania. Demographic data were collected from 252 patients with suspected allergic contact dermatitis. Pacients were patch tested with 28-allergen EBS.The positive patch test was observed in 80.16% patients. The most prevalent contact allergens were nickel sulphate (15.08%), fragrance mix I & II (13.10%) and potassium dichromate (9.52%). Differences in sensitization prevalences to some allergens of the EBS compared with other European countries were recognized. The current EBS is a suitable diagnostic tool for contact allergy in Romania.


2019 ◽  
Vol 76 (Suppl 1) ◽  
pp. A88.2-A88
Author(s):  
Heng-Hao Chang ◽  
Bour-Jr Wang ◽  
How-Ran Guo ◽  
I-Ru Lee

BackgroundOccupational skin disease (OSD) is one of the most common occupational disorders in Taiwan. As reporting OSD was not compulsory, there was limited information on the exact causes and patient characteristics. The objective of this study was to investigate the causes and common allergens among OSD patients in Taiwan.MethodsWe recruited patients from Occupational Dermatology Clinic in National Cheng Kung University Hospital, a tertiary referral center in Tainan city, between 1 January 2010 and 31 July 2017. Patch testing with European baseline series, additional occupation-oriented series, and personal material exposed at work or during daily life was carried out if the patients were suspected of allergic skin diseases.ResultsAmong the 273 patients who received patch testing, 51 (18.7%) patients had a final diagnosis of OSD. 82.4% of the 51 patients were diagnosed with allergic contact dermatitis (ACD), 11.8% with irritant contact dermatitis (ICD), while the rest 5.9% with both. Patient reported 3.0 years of skin problem prior to the clinic visit. The vast majority of patients suffered from hand eczema. Epoxy resin workers, food workers, hairdressers and beauty salon beauticians were the most common occupations related to OSD. The most important allergens were nickel, fragrance mix I, potassium dichromate and paraben mix. Around half of the patients showed allergic reaction to their personal material.DiscussionAs worker compensation statistics may not accurately estimate the characteristics of OSD patients, our study was crucial to identify the high-risk groups as well as the common allergens related to their work. Although the results might not represent the proportion of patients of OSD in other clinic, drawing information from patch testing may reflect those patients of severer or longer duration of symptoms. Future occupational measures should be taken on these industries for the detection and prevention of OSD.


Dermatitis ◽  
1998 ◽  
Vol 9 (2) ◽  
pp. 92-95 ◽  
Author(s):  
Meredith Klein Kosann ◽  
Ronald R. Brancaccio ◽  
Jerome L. Shupack ◽  
Andrew G. Franks ◽  
David E. Cohen

Author(s):  
S. Jyothi Lakshmi ◽  
K. Gopalakrishnan

<p class="abstract"><strong>Background:</strong> Hand eczema is a common dermatological problem resulting from both allergic and irritant contactants. Patch testing helps in both diagnosing and identifying allergens.</p><p class="abstract"><strong>Methods:</strong> A cross sectional study wherein 110 patients with hand eczema attending Dermatology OPD were included and patch testing was done. Data was collected from April 2015 to July 2016 and was analysed for clinical and epidemiological characteristics.<strong></strong></p><p class="abstract"><strong>Results:</strong> The mean age of the patients studied was 40.27 years with male preponderance. Housewives were the major occupational group comprising 25.5% followed by masons 21.8% and farmers 10.9%. The commonest morphological type was hyperkeratotic type constituting 51.85%, followed by fingertip eczema 19.1%, discoid eczema 11.8%, wear and tear dermatitis 8.2%, recurrent focal palmar peeling 4.5% and pompholyx 4.5%. In the study group 60% of patients showed positive patch test result. A total 66 patients showed patch test positivity to a total of 69 allergens. Nickel was the most common allergen 27.3% identified followed by potassium dichromate 10.9%. Among female patients with positive patch test 70% reacted to nickel and similarly 83.5% of male patients reacted to potassium dichromate. Parthenium allergy was seen in 41.5% of farmers studied.</p><p class="abstract"><strong>Conclusions:</strong> Patch testing has a definitive role in diagnosing hand eczema caused by allergens. Identifying the allergen involved helps the clinician in advising the patient regarding further avoidance of contactants.</p>


Author(s):  
V. N. S. Ahamed Shariff ◽  
K. Deepa ◽  
L. Balamurugan ◽  
S. Nirmala

<p class="abstract"><strong>Background:</strong> Allergic contact dermatitis is common dermatoses seen among patients attending dermatology clinics. Allergic contact dermatitis is due to delayed type of hypersensitivity reaction. The diagnosis of allergic contact dermatitis is made by patch testing. A positive reaction to a patch test commonly proves the cause of dermatitis.</p><p class="abstract"><strong>Methods:</strong> A retrospective study was conducted<strong> </strong>to estimate the incidence of various allergens among 150 patch test positive patients with allergic contact dermatitis who had attended the dermatology OPD in Rajiv Gandhi Government General Hospital, Chennai, between October 2014 and September 2016. All the details regarding history, examination findings, investigations and patch test results were collected from case records, the data were tabulated and analysed.<strong></strong></p><p class="abstract"><strong>Results:</strong> Allergic contact dermatitis to cement was the commonest (44.7%), followed by nickel (10%) and plant antigens (9.3%). The commonest allergen to be tested positive was Potassium dichromate (82 cases), followed nickel (15 cases) and formaldehyde (8 cases). Most of the patients were in the age category between 41 and 50 years (47 cases– 31.33%). Male to female ratio was 2.41:1. 14 were atopic individuals (9.33%) by Hanifin and Rajka's criteria. Allergic contact dermatitis in 103 cases of our study were of occupational in origin (67%).</p><p><strong>Conclusions:</strong> Avoidance of allergen and proper preventive measures in workplace and day to day activities will lead to significant decrease in the morbidity of the disease and improvement in quality of life in patients with allergic contact dermatitis. </p>


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