Autonomic control of the peripheral vascular system

1970 ◽  
Vol 125 (4) ◽  
pp. 716-724 ◽  
Author(s):  
A. J. Edis
Keyword(s):  
Vascular System ◽  
Autonomic Control ◽  
Peripheral Vascular

scholarly journals Pilot Study: Quantitative Photoacoustic Evaluation of Peripheral Vascular Dynamics Induced by Carfilzomib In Vivo

Sensors ◽  
2021 ◽  
Vol 21 (3) ◽  
pp. 836
Author(s):  
Thi Thao Mai ◽  
Manh-Cuong Vo ◽  
Tan-Huy Chu ◽  
Jin Young Kim ◽  
Chulhong Kim ◽  
...  
Keyword(s):  
Pilot Study ◽  
Side Effects ◽  
Cardiovascular Events ◽  
Evaluation Method ◽  
Vascular System ◽  
Maximum Amplitude ◽  
Peripheral Vascular ◽  
Peripheral Vasculature ◽  
Mouse Ear

Carfilzomib is mainly used to treat multiple myeloma. Several side effects have been reported in patients treated with carfilzomib, especially those associated with cardiovascular events, such as hypertension, congestive heart failure, and coronary artery disease. However, the side effects, especially the manifestation of cardiovascular events through capillaries, have not been fully investigated. Here, we performed a pilot experiment to monitor peripheral vascular dynamics in a mouse ear under the effects of carfilzomib using a quantitative photoacoustic vascular evaluation method. Before and after injecting the carfilzomib, bortezomib, and PBS solutions, we acquired high-resolution three-dimensional PAM data of the peripheral vasculature of the mouse ear during each experiment for 10 h. Then, the PAM maximum amplitude projection (MAP) images and five quantitative vascular parameters, i.e., photoacoustic (PA) signal, diameter, density, length fraction, and fractal dimension, were estimated. Quantitative results showed that carfilzomib induces a strong effect on the peripheral vascular system through a significant increase in all vascular parameters up to 50%, especially during the first 30 min after injection. Meanwhile, bortezomib and PBS do not have much impact on the peripheral vascular system. This pilot study verified PAM as a comprehensive method to investigate peripheral vasculature, along with the effects of carfilzomib. Therefore, we expect that PAM may be useful to predict cardiovascular events caused by carfilzomib.

scholarly journals The dependence of the cardiac effects of nifedipine on the responses of the peripheral vascular system.

Circulation ◽  
1984 ◽  
Vol 69 (5) ◽  
pp. 963-972 ◽  
Author(s):  
P B Kurnik ◽  
A J Tiefenbrunn ◽  
P A Ludbrook
Keyword(s):  
Vascular System ◽  
Peripheral Vascular ◽  
Cardiac Effects

scholarly journals CORP: Ultrasound assessment of vascular function with the passive leg movement technique

2017 ◽  
Vol 123 (6) ◽  
pp. 1708-1720 ◽  
Author(s):  
Jayson R. Gifford ◽  
Russell S. Richardson
Keyword(s):  
Vascular Function ◽  
Cardiovascular Health ◽  
Vascular System ◽  
The Elderly ◽  
Passive Movement ◽  
Flow Mediated Dilation ◽  
Peripheral Vascular ◽  
Ultrasound Assessment ◽  
Leg Movement ◽  
Hyperemic Response

As dysfunction of the vascular system is an early, modifiable step in the progression of many cardiovascular diseases, there is demand for methods to monitor the health of the vascular system noninvasively in clinical and research settings. Validated by very good agreement with more technical assessments of vascular function, like intra-arterial drug infusions and flow-mediated dilation, the passive leg movement (PLM) technique has emerged as a powerful, yet relatively simple, test of peripheral vascular function. In the PLM technique, the change in leg blood flow elicited by the passive movement of the leg through a 90° range of motion is quantified with Doppler ultrasound. This relatively easy-to-learn test has proven to be ≤80% dependent on nitric oxide bioavailability and is especially adept at determining peripheral vascular function across the spectrum of cardiovascular health. Indeed, multiple reports have documented that individuals with decreased cardiovascular health such as the elderly and those with heart failure tend to exhibit a substantially blunted PLM-induced hyperemic response (~50 and ~85% reduction, respectively) compared with populations with good cardiovascular health such as young individuals. As specific guidelines have not yet been put forth, the purpose of this Cores of Reproducibility in Physiology (CORP) article is to provide a comprehensive reference for the assessment and interpretation of vascular function with PLM with the aim to increase reproducibility and consistency among studies and facilitate the use of PLM as a research tool with clinical relevance.

scholarly journals Peripheral vascular system thrombosis and COVID-19: A chilling revelation

2021 ◽  
Vol 8 (3) ◽  
pp. 208
Author(s):  
SyedMohammed Ali Ahmed ◽  
CSaravanan Robinson ◽  
DN Sharmila ◽  
SK Balaji ◽  
SudharsanReddy Yalamuru
Keyword(s):  
Vascular System ◽  
Peripheral Vascular

ANGIOMATOSIS (HAMARTOMATOUS HEM-LYMPHANGIOMATOSIS)

PEDIATRICS ◽  
1961 ◽  
Vol 28 (1) ◽  
pp. 65-76
Author(s):  
Peter J. Koblenzer ◽  
Martin J. Bukowski
Keyword(s):  
Blood Vessels ◽  
Lymphatic System ◽  
Vascular System ◽  
Clinical Manifestations ◽  
Body Cavity ◽  
Histologic Examination ◽  
Peripheral Vascular ◽  
Osteolytic Lesions ◽  
System A

A case is described of a diffuse, possibly generalized, abnormality of a hamartomatous nature of the peripheral vascular system. A number of cases from the literature, which also appear to belong in this category, are summarized. Histologic examination shows that lymph and blood vessels may both be involved, though this may be essentially an abnormality of the lymphatic system in which extensive venolymphatic communications occur. The clinical manifestations vary according to the site of involvement and the extent of dissemination and also according to whether the lesions are predominantly hemangiomatous or lymphangiomatous. The main features are osteolytic lesions, visceromegaly, cutaneous hemangiomas or lymphangiomas and massive effusions into any body cavity. The effusions are usually chylous, sanguineous or a mixture of both. Any or all of these features may be present in any one case. The disease frequently has its onset in childhood or adolescence and tends to be progressive. If the lesions are widely disseminated or an effusion into a body cavity is present the outlook is grave. Treatment so far has been unsuccessful. Surgery may occasionally have a place. The term angiomatosis is employed to denote this condition not only to underline its potentially extensive nature but also to avoid debate as to whether it is essentially hemangiomatosis or lymphangiomatosis.

Triple-TWIST MRA: high spatial and temporal resolution MR angiography of the entire peripheral vascular system using a time-resolved 4D MRA technique

2012 ◽  
Vol 23 (1) ◽  
pp. 298-306 ◽  
Author(s):  
Sonja Kinner ◽  
Harald H. Quick ◽  
Stefan Maderwald ◽  
Peter Hunold ◽  
Jörg Barkhausen ◽  
...  
Keyword(s):  
Temporal Resolution ◽  
Mr Angiography ◽  
Vascular System ◽  
Peripheral Vascular ◽  
Time Resolved
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