scholarly journals Calcium Channel Blockers and Mortality in Elderly Patients With Myocardial Infarction

1999 ◽  
Vol 159 (19) ◽  
Author(s):  
James G. Jollis ◽  
Ross J. Simpson ◽  
Mridul K. Chowdhury ◽  
Wayne E. Cascio ◽  
John R. Crouse ◽  
...  
2002 ◽  
Vol 11 (6) ◽  
pp. 487-492 ◽  
Author(s):  
Yoshiharu Ohyama ◽  
Kazuhiro Funao ◽  
Eri Kawabe ◽  
Doubun Hayashi ◽  
Tsutomu Yamazaki ◽  
...  

1995 ◽  
Vol 52 (13) ◽  
pp. 1460-1462 ◽  
Author(s):  
Bradley G. Phillips ◽  
Lori L. MacFarlane ◽  
Deborah Stier Carson

1999 ◽  
Vol 47 (5) ◽  
pp. 512-517 ◽  
Author(s):  
Matthew W. Gillman ◽  
Dennis Ross-Degnan ◽  
Thomas J. McLaughlin ◽  
Xiaoming Gao ◽  
Donna Spiegelman ◽  
...  

2021 ◽  
Vol 12 (3) ◽  
pp. 3117-3134

1,4-Dihydropyridines are a group of pyridine-based molecules possessing a magnificent set of biological and therapeutic potentials. Belonging to the class of calcium channel blockers, they are known to be effective in the conditions, angina, hypertension, myocardial infarction and show vasodilatory and cardiac depressant effects. Hypotensive, antimicrobial, anticancer, anticoagulant, antioxidant, anticonvulsant, antimalarial, antiulcer, and neuroprotective effects have been reported with their rational use. The effects are precipitated in response to inhibition of calcium channels, gradually restricting calcium influx. Drugs like nifedipine, felodipine, and amlodipine are commonly used clinically. Several other drugs belonging to this class have been under clinical trials. The present review focuses on the various 1,4-dihydropyridine derivatives and their pharmacological actions.


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