scholarly journals The Relationship Between Magnitude of Proteinuria Reduction and Risk of End-stage Renal Disease

2005 ◽  
Vol 165 (8) ◽  
pp. 947 ◽  
Author(s):  
Janice Lea
2020 ◽  
Vol 45 (2) ◽  
pp. 180-193
Author(s):  
Ying Liu ◽  
Luping Wang ◽  
Xianfeng Han ◽  
Yang Wang ◽  
Xuefeng Sun ◽  
...  

Background: Hemodialysis is the main approach for renal replacement therapy in patients with end-stage renal disease (ESRD) in China. The timing of dialysis initiation is one of the key factors influencing patient survival and prognosis. Over the past decade, the relationship between the timing of dialysis initiation and mortality has remained unclear in patients with ESRD in China. Methods: Patients who commenced maintenance hemodialysis from 2009 to 2014 from 24 hemodialysis centers in Mainland China were enrolled in the study (n = 1,674). Patients were divided into 2 groups based on the year they started hemodialysis (patients who started hemodialysis from 2009 to 2011, and patients who started hemodialysis from 2012 to 2014). Analysis of the yearly change in the estimated glomerular filtration rate (eGFR) at the initiation of dialysis was performed for the 2 groups. Meanwhile, the patients were divided into 3 groups based on their eGFR at the initiation of dialysis (<4, 4–8, and >8 mL/min/1.73 m2). For these 3 groups, the relationship between the eGFR at the start of dialysis and mortality were analyzed. Results: The average eGFRs were 5.68 and 5.94 mL/min/1.73 m2 for 2009–2011 and 2012–2014, respectively. Compared with the 2009–2011 group, the proportion of patients with diabetes in 2012–2014 increased from 26.7 to 37.7%. The prognosis of patients with different eGFRs at the start of dialysis was analyzed using Kaplan-Meier survival curves. After adjusting for confounding factors through a Cox regression model, no significant difference was demonstrated among the 3 groups (<4 mL/min/1.73 m2 was used as the reference, in comparison with 4–8 mL/min/1.73 m2 [p = 0.681] and >8 mL/min/1.73 m2 [p = 0.403]). Conclusion: In Mainland China, the eGFR at the start of dialysis did not change significantly over time from 2008 to 2014 and had no association with the mortality of patients with ESRD.


1998 ◽  
Vol 82 (1) ◽  
pp. 331-336 ◽  
Author(s):  
Roger C. Katz ◽  
Jay Ashmore ◽  
El Via Barboa ◽  
Karen Trueblood ◽  
Veronica McLaughlin ◽  
...  

Noncompliance is a common problem in patients with end-stage renal disease. In this study, we assessed the relationship between knowledge of disease and dietary compliance in a cohort of 56 dialysis patients. Based on a health belief model of adherence, we predicted that dialysis patients who knew more about kidney disease and its treatment would be more compliant than those who knew less about these matters. We also examined the relationship between dietary compliance and patients' emotional well-being. We used a composite measure of compliance consisting of serum K, P, and interdialytic weight gain. A 30-item “Kidney Disease Questionnaire” was used to assess patients' knowledge of their illness. Contrary to prediction, compilers did not score higher on the knowledge questionnaire; in fact, the observed correlation of .32 was in the opposite direction. In the same vein, we found no relationship between compliance and emotional well-being. These results, although somewhat surprising, add to a growing body of research which indicates that medical compliance involves more than educating patients about the mechanisms and treatment of their illness.


2020 ◽  
Vol 4 (1) ◽  
Author(s):  
Khairina Zahra ◽  
Chiyar Edison

<div><p class="Keywords"><strong>Objective: </strong>Hemodialysis therapy management consists of four main aspects; hemodialysis program, medication, fluid restriction, and diet. One of important factors in patients’ adherence to hemodialysis therapy is the relationship between health care providers and patients. Nurses have a great role in improving patients’ adherence since they have the most acquaintances with patients. The purpose of this study was to identify the association between caring nurses’ behaviors and respondent characteristics with adherence to hemodialysis therapy management in end- stage renal disease patients.<strong> </strong></p><p class="Keywords"><strong>Methods: </strong>This study employed a descriptive quantitative research design with a cross sectional approach. A purposive sample of 97 ESRD patients on hemodialysis were involved in this study. data were collected using questionnaire to identify patients’ characteristics, perception on nurses caring behaviors, and compliance on hemodialysis therapy management. Data were analyzed using univariate and bivariate analyses.</p><p class="Keywords"><strong>Results: </strong>Over half of the patients were adherent to hemodialysis therapy management (50.5%) and perceived that nurses have caring behaviors (54.6%). Age, gender, education, economic and marital status were not associated with patients’ adherence. In addition, nurses caring behaviors were not related with patients’ adherence. In contrast, family support was significantly linked with patients’ adherence (p = 0.033).</p><p class="Keywords"><strong>Conclusion: </strong>Nurses caring behaviors were not related to patients’ adherence but family support was. Nurses need to involve family in nursing care as appropriate to better improve patients’ adherence.<strong> </strong></p><p class="Keywords"><strong>Key words: </strong>end- stage renal disease, nurses’ caring behaviors, patients’ adherence  <strong></strong></p></div>


2019 ◽  
Vol 20 (1) ◽  
Author(s):  
Mignote Hailu Gebrie ◽  
Jodi Ford

Abstract Background Research suggests that patients with end stage renal disease undergoing hemodialysis have a higher rate of depression and dietary non adherence leading to hospitalization and mortality. The purpose of this review was to synthesize the quantitative evidence on the relationship between depressive symptoms and dietary non adherence among end stage renal disease (ESRD) patients receiving hemodialysis. Methods A systematic review was undertaken. Three electronic databases were searched including PubMed, CINHAL and Web of Science. Only quantitative studies published between 2001 and 2016 were included in the review. Result A total of 141 publications were reviewed during the search process and 28 articles that fulfilled the inclusion criteria were included in the review. Eleven studies (39.3%) reported on the prevalence of depressive symptoms or depression and its effect on patient outcomes. Ten studies (35.7%) focused on dietary adherence/non adherence in patients with ESRD and the remaining seven (25%) articles were descriptive studies on the relationship between depressive symptoms and dietary non adherence in patients with ESRD receiving hemodialysis. The prevalence of depressive symptoms and dietary non adherence ranged as 6–83.49% and from 41.1–98.3% respectively. Decreased quality of life & increased morbidity and mortality were positively associated with depressive symptoms. Other factors including urea, hemoglobin, creatinine and serum albumin had also association with depressive symptoms. Regarding dietary non adherence, age, social support, educational status, behavioral control and positive attitudes are important factors in ESRD patients receiving hemodialysis. Having depressive symptoms is more likely to increase dietary non adherence. Conclusion Depressive symptoms and dietary non adherence were highly prevalent in patients with end stage renal disease receiving hemodialysis therapy. Nearly all of the articles that examined the relationship between depressive symptoms and dietary non adherence found a significant association. Future research using experimental or longitudinal design and gold standard measures with established cut-points is needed to further explain the relationship.


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