Blood-volume studies in cardiac-surgery patients

JAMA ◽  
1966 ◽  
Vol 195 (5) ◽  
pp. 356-361 ◽  
Author(s):  
J. B. McClenahan
Keyword(s):  
Cardiac Surgery ◽  
Blood Volume

Perioperative red cell, plasma, and blood volume change in patients undergoing cardiac surgery

Transfusion ◽  
2006 ◽  
Vol 46 (3) ◽  
pp. 392-397 ◽  
Author(s):  
Robert D. Slight ◽  
Norzeihan J. Bappu ◽  
Onyekwelu C. Nzewi ◽  
D. Brian L. McClelland ◽  
Pankaj S. Mankad
Keyword(s):  
Cardiac Surgery ◽  
Blood Volume ◽  
Volume Change ◽  
Red Cell ◽  
Cell Plasma

Intrathoracic blood volume index measured by thermodilution for preload monitoring after cardiac surgery

2002 ◽  
Vol 16 (2) ◽  
pp. 191-195 ◽  
Author(s):  
Daniel A. Reuter ◽  
Thomas W. Felbinger ◽  
Karl Moerstedt ◽  
Florian Weis ◽  
Christian Schmidt ◽  
...  
Keyword(s):  
Cardiac Surgery ◽  
Blood Volume ◽  
Intrathoracic Blood Volume ◽  
Volume Index ◽  
Intrathoracic Blood Volume Index

scholarly journals Effect of Intra- and Post-Operative Fluid and Blood Volume on Postoperative Pulmonary Edema in Patients with Intraoperative Massive Bleeding

2021 ◽  
Vol 10 (18) ◽  
pp. 4224
Author(s):  
Young-Suk Kwon ◽  
Haewon Kim ◽  
Hanna Lee ◽  
Jong-Ho Kim ◽  
Ji-Su Jang ◽  
...  
Keyword(s):  
Cardiac Surgery ◽  
Risk Factor ◽  
Confidence Interval ◽  
Pulmonary Edema ◽  
Red Blood Cells ◽  
Blood Volume ◽  
Blood Cells ◽  
Massive Bleeding ◽  
Hazard Ratio ◽  
Blood Volumes

In patients with intraoperative massive bleeding, the effects of fluid and blood volume on postoperative pulmonary edema are uncertain. Patients with intraoperative massive bleeding who had undergone a non-cardiac surgery in five hospitals were enrolled in this study. We evaluated the association of postoperative pulmonary edema risk and intra- and post-operatively administered fluid and blood volumes in patients with intraoperative massive bleeding. In total, 2090 patients were included in the postoperative pulmonary edema analysis, and 300 patients developed pulmonary edema within 72 h of the surgery. The postoperative pulmonary edema with hypoxemia analysis included 1660 patients, and the condition occurred in 161 patients. An increase in the amount of red blood cells transfused per hour after surgery increased the risk of pulmonary edema (hazard ratio: 1.03; 95% confidence interval: 1.01–1.05) p = 0.013) and the risk of pulmonary edema with hypoxemia (hazard ratio: 1.04; 95% confidence interval: 1.01–1.07; p = 0.024). An increase in the red blood cells transfused per hour after surgery increased the risk of developing pulmonary edema. This increase can be considered as a risk factor for pulmonary edema.

scholarly journals Prevention of postoperative bleeding after complex pediatric cardiac surgery by early administration of fibrinogen, prothrombin complex and platelets: a prospective observational study

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Nils Dennhardt ◽  
Robert Sümpelmann ◽  
Alexander Horke ◽  
Oliver Keil ◽  
Katja Nickel ◽  
...  
Keyword(s):  
Cardiac Surgery ◽  
Observational Study ◽  
Blood Volume ◽  
Prospective Observational Study ◽  
Postoperative Bleeding ◽  
Maximum Amplitude ◽  
Mean Value ◽  
Pediatric Cardiac Surgery ◽  
Early Administration ◽  
Coagulation Parameters

Abstract Background Postoperative bleeding is a major problem in children undergoing complex pediatric cardiac surgery. The primary aim of this prospective observational study was to evaluate the effect of an institutional approach consisting of early preventive fibrinogen, prothrombin complex and platelets administration on coagulation parameters and postoperative bleeding in children. The secondary aim was to study the rate of re-intervention and postoperative transfusion, the occurrence of thrombosis, length of mechanical ventilation, ICU stay and mortality. Methods In fifty children (age 0–6 years) with one or more predefined risk factors for bleeding after cardiopulmonary bypass (CPB), thrombelastography (TEG) and standard coagulation parameters were measured at baseline (T1), after CPB and reversal of heparin (T2), at sternal closure (T3) and after 12 h in the ICU (T4). Clinical bleeding was evaluated by the surgeon at T2 and T3 using a numeric rating scale (NRS, 0–10). Results After CPB and early administration of fibrinogen, prothrombin complex and platelets, the clinical bleeding evaluation score decreased from a mean value of 6.2 ± 1.9 (NRS) at T2 to a mean value of 2.1 ± 0.8 at T3 (NRS; P <  0.001). Reaction time (R), kinetic time (K), maximum amplitude (MA) and maximum amplitude of fibrinogen (MA-fib) improved significantly (P <  0.001 for all), and MA-fib correlated significantly with the clinical bleeding evaluation (r = 0.70, P <  0.001). The administered total amount of fibrinogen (mg kg− 1) correlated significantly with weight (r = − 0.42, P = 0.002), priming volume as percentage of estimated blood volume (r = 0.30, P = 0.034), minimum CPB temperature (r = − 0.30, P = 0.033) and the change in clinical bleeding evaluation from T2 to T3 (r = 0.71, P <  0.001). The incidence of postoperative bleeding (> 10% of estimated blood volume) was 8%. No child required a surgical re-intervention, and no cases of thrombosis were observed. Hospital mortality was 0%. Conclusion In this observational study of children with an increased risk of bleeding after CPB, an early preventive therapy with fibrinogen, prothrombin complex and platelets guided by clinical bleeding evaluation and TEG reduced bleeding and improved TEG and standard coagulation parameters significantly, with no occurrence of thrombosis or need for re-operation. Trial registration German Clinical Trials Register DRKS00018109 (retrospectively registered 27th August 2019).

Trendelenburg positioning after cardiac surgery: effects on intrathoracic blood volume index and cardiac performance

2005 ◽  
Vol 20 (1) ◽  
pp. 17-20 ◽  
Author(s):  
D. A. Reuter ◽  
T. W. Felbinger ◽  
C. Schmidt ◽  
K. Moerstedt ◽  
E. Kilger ◽  
...  
Keyword(s):  
Cardiac Surgery ◽  
Blood Volume ◽  
Cardiac Performance ◽  
Intrathoracic Blood Volume ◽  
Volume Index ◽  
Intrathoracic Blood Volume Index

Plasma, red cell, and total blood volume changes following cardiac surgery

1955 ◽  
Vol 50 (2) ◽  
pp. 163-171
Author(s):  
William Likoff ◽  
Donald Berkowitz ◽  
Samuel V. Geyer ◽  
Herbert Strauss ◽  
Attilio Reale
Keyword(s):  
Cardiac Surgery ◽  
Blood Volume ◽  
Red Cell ◽  
Total Blood Volume ◽  
Volume Changes ◽  
Total Blood

Trendelenburg positioning after cardiac surgery: effects on intrathoracic blood volume index and cardiac performance

2003 ◽  
Vol 20 (1) ◽  
pp. 17-20 ◽  
Author(s):  
D. A. Reuter ◽  
T. W. Felbinger ◽  
C. Schmidt ◽  
K. Moerstedt ◽  
E. Kilger ◽  
...  
Keyword(s):  
Cardiac Surgery ◽  
Blood Volume ◽  
Cardiac Performance ◽  
Intrathoracic Blood Volume ◽  
Volume Index ◽  
Intrathoracic Blood Volume Index

Comparison of stored red blood cell washing techniques for priming extracorporeal circuits

Perfusion ◽  
2017 ◽  
Vol 33 (2) ◽  
pp. 130-135 ◽  
Author(s):  
Jun Sasaki ◽  
Christopher Tirotta ◽  
Hyunsoo Lim ◽  
Kathleen Kubes ◽  
Jane Salvaggio ◽  
...  
Keyword(s):  
Cardiac Surgery ◽  
Blood Cell ◽  
Operating Room ◽  
Blood Volume ◽  
Red Blood Cell ◽  
Normal Saline ◽  
Blood Cells ◽  
Blood Bank ◽  
Extracorporeal Circuits ◽  
Sodium And Potassium

Background: The aim of this study was to compare three different blood washing techniques and describe the differences for the composition of the washed red blood cells (RBC). Methods: Stored RBCs less than 5 days old were washed using three different techniques. 1) Washing with normal saline with the COBE Model 2991 blood processor in the blood bank (BB-S). 2) Washing with normal saline with the Continuous AutoTransfusion System (C.A.T.S) in the operating room (OR-S). 3) Washing with Plasma-Lyte with the C.A.T.S in the operating room (OR-PL). Then, we compared the values for hemoglobin (Hb), hematocrit (Hct), blood volume, RBC volume, lactate, glucose, sodium and potassium of the three different groups. Results: Forty-five units of RBCs were washed and analyzed (15 for each technique). The OR-S RBCs, when compared to the BB-S RBCs, had lower hemoglobin (g/dL) (22.8 vs 24.1, p=0.006), lower hematocrit (%) (67 vs 71, p=0.006), higher RBC volume (ml) (161 vs 130, p<0.001), higher glucose (mg/dL) (185 vs 46, p<0.001) and lower sodium (mmol/L) (153 vs 158, p<0.001). When compared to the OR-S RBCs, the OR-PL RBCs showed higher potassium (mmol/L) (5.3 vs 2, p<0.001) and lower sodium (mmol/L) (129 vs 153, p<0.001). Conclusion: RBCs washed with an autotransfusion device had a higher RBC volume and more physiological levels of glucose and sodium when compared with the blood processor in the blood bank. It can be an alternative option to use RBCs washed with an autotransfusion device for priming the extracorporeal circuits utilized in patients undergoing cardiac surgery.

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