From the NIH: TORCH package antibody tests not recommended for routine screening of pregnant women

JAMA ◽  
1982 ◽  
Vol 247 (18) ◽  
pp. 2477-2478
Keyword(s):  
Pregnant Women ◽  
Routine Screening ◽  
Antibody Tests

scholarly journals Screening for Coxiella burnetii infection during pregnancy: pros and cons according to the Wilson and Jungner criteria

2012 ◽  
Vol 17 (3) ◽  
Author(s):  
J M Munster ◽  
L M Steggerda ◽  
A C Leenders ◽  
J G Aarnoudse ◽  
E Hak
Keyword(s):  
High Risk ◽  
Pregnant Women ◽  
Coxiella Burnetii ◽  
Q Fever ◽  
Risk Group ◽  
High Risk Group ◽  
Routine Screening ◽  
Maternal Complications ◽  
Clinical Consequences ◽  
Pros And Cons

In Europe the incidence of human Q fever has dramatically increased over the previous years. Untreated infections with Coxiella burnetii, the causal agent of Q fever, have been associated with both obstetric and maternal complications. The majority of pregnant women with a C. burnetii infection remain asymptomatic, hence screening could be of value to prevent unwanted outcomes in this high-risk group. We applied the updated Wilson and Jungner criteria to review the evidence for routine screening for C. burnetii infection during pregnancy. Since much uncertainty remains about the incidence, clinical consequences, diagnostics and treatment of C. burnetii infection during pregnancy, routine screening for C. burnetii infection during pregnancy should not be recommended. Rigorous studies to assess the effectiveness of C. burnetii screening are warranted.

Gonococcal Ophthalmia Neonatorum and Routine Screening of Pregnant Women for Gonorrheal Infection

PEDIATRICS ◽  
1973 ◽  
Vol 52 (2) ◽  
pp. 302-303
Author(s):  
Hania W. Ris
Keyword(s):  
Prenatal Care ◽  
Pregnant Women ◽  
Silver Nitrate ◽  
Prophylactic Treatment ◽  
Routine Screening ◽  
Significant Frequency ◽  
Ophthalmia Neonatorum

Drs. Snowe and Wilfert's1 timely paper on epidemic reappearance of gonococcal ophthalmia neonatorum calls attention to a very serious problem. Recently in Wisconsin a case of gonococcal ophthalmia was reported2 in a 3-day-old infant who received silver nitrate prophylactic treatment. The prenatal care consisted of 14 visits to an obstetrician, which did not include screening for gonorrhea. The author's statement in the summary "gonorrhea occurs with significant frequency in obstetrical groups to merit attempts at therapy of the gravid mother" could be misinterpreted as advocating treatment without establishing a diagnosis.

scholarly journals Routine screening for SARS CoV-2 in unselected pregnant women at delivery

PLoS ONE ◽  
2020 ◽  
Vol 15 (9) ◽  
pp. e0239887
Author(s):  
Pilar Díaz-Corvillón ◽  
Max Mönckeberg ◽  
Antonia Barros ◽  
Sebastián E. Illanes ◽  
Arturo Soldati ◽  
...  
Keyword(s):  
Pregnant Women ◽  
Routine Screening

Pregnant Women's Attitudes and Knowledge in Relation to Access to Serum-Alpha-Fetoprotein Test

1988 ◽  
Vol 16 (4) ◽  
pp. 197-204 ◽  
Author(s):  
Marie-Louise Sandén ◽  
Per Bjurulf
Keyword(s):  
Pregnant Women ◽  
Prenatal Screening ◽  
Alpha Fetoprotein ◽  
Routine Screening ◽  
Consecutive Series ◽  
Testing Procedures ◽  
Serum Alpha Fetoprotein ◽  
Level Of Knowledge ◽  
Attitudes And Knowledge ◽  
Antenatal Clinics

Serum-Alpha-Fetoprotein (se-AFP) screening is a controversial issue in Sweden. In some areas the test has never been offered, in others it is routinely offered to all pregnant women and there are areas where the se-AFP test has been offered but is no longer available but for very special indications. This pseudoexperimental situations was used to analyze the effects of different information environments on attitudes to and knowledge of testing procedures at the antenatal clinics, especially the se-AFP test, and anxiety of malformations. Consecutive series of pregnant women in these three areas filled in questionnaires at their first visit, in the 22nd to 24th, and the 32nd to 35th weeks of pregnancy, and after delivery. The attitudes to prenatal screening were most positive in the routine screening area and most negative in the area which previously but no longer offers the test. The level of knowledge was somewhat higher in the routine screening area at the first visit to the clinic and increased substantially, especially in the routine screening area.

scholarly journals Role ofToxoplasmaIgA as Part of a Reference Panel for the Diagnosis of Acute Toxoplasmosis during Pregnancy

2018 ◽  
Vol 57 (2) ◽  
Author(s):  
Tudor Rares Olariu ◽  
Brian G. Blackburn ◽  
Cindy Press ◽  
Jeanne Talucod ◽  
Jack S. Remington ◽  
...  
Keyword(s):  
Pregnant Women ◽  
The United States ◽  
Reference Laboratory ◽  
Content Type ◽  
Igm Antibody ◽  
Iga Antibodies ◽  
Iga Antibody ◽  
Acute Toxoplasmosis ◽  
Antibody Tests ◽  
Toxoplasmosis During Pregnancy

ABSTRACTThis study evaluated the usefulness of adding theToxoplasma gondiiIgA antibody enzyme-linked immunosorbent assay (ELISA) to the serologic panel of tests done for the diagnosis of acute toxoplasmosis in pregnant women in a reference laboratory in the United States. We conducted a retrospective study of 690 consecutive pregnant women with positiveT. gondiiIgG antibody test results who also hadT. gondiiIgA and IgM antibody tests performed. Patients were defined as acutely or chronically infected withT. gondiibased on a panel of serologic tests performed at the Palo Alto Medical Foundation Toxoplasma Serology Laboratory (PAMF-TSL). Among the 81 women who were positive byT. gondiiIgA antibody ELISA testing, 61 (75.3%) were acutely infected withT. gondii, while of the 547 who were negative by IgA testing, only 24 (4.4%) were acutely infected (P < 0.001). Among the 71 women who were positive by both IgA and IgM antibody tests, 61 (85.9%) were acutely infected, whereas 24 (19.2%) of the 125 women who were positive by only the IgM ELISA were acutely infected (P < 0.001). These results demonstrate that pregnant women withT. gondiiIgA antibodies are more likely than pregnant women withoutT. gondiiIgA antibodies to have had a recent infection withT. gondii.ToxoplasmaIgA antibody testing can therefore improve the accuracy of a serologic panel for the diagnosis of acute toxoplasmosis during pregnancy. Physicians who ordered testing only forT. gondiiIgG and IgM should also request additional testing for IgA and IgG avidity, if both IgG and IgM are positive. This further testing should, ideally, be performed in a reference laboratory.

scholarly journals Routine screening of antenatal population for thyroid disorders-mandatory

2018 ◽  
Vol 7 (7) ◽  
pp. 2834
Author(s):  
Kaliki Hymavathi ◽  
Malini Devi Gottipati ◽  
Tejaswini Jakka ◽  
Bhavana T. C.
Keyword(s):  
Pregnant Women ◽  
Pregnancy Outcomes ◽  
Thyroid Dysfunction ◽  
Thyroid Stimulating Hormone ◽  
Routine Screening ◽  
Overt Hypothyroidism ◽  
Thyroid Peroxidase ◽  
Thyroid Disorders ◽  
Thyroid Function Tests ◽  
Successful Pregnancy

Background: Thyroid dysfunction is commonly seen in pregnant women causing adverse maternal and fetal effects. Routine screening of antenatal population for the same will be helpful for successful pregnancy outcomes. The objective of this study is to detect and treat antenatal women with Thyroid dysfunction to avoid deleterious maternal/ fetal effects.Methods: The present study is a hospital based prospective study conducted in the department of Obstetrics and Gynaecology of Narayana Medical College and Hospital(NMCH), Nellore, Andhra Pradesh, India. 1000 pregnant women were randomly recruited into this study. Apart from routine antenatal investigations, Thyroid function tests (TFT) - Thyroid stimulating hormone (TSH), freeT4 (fT4) and Thyroid peroxidase antibody (TPO Ab) are done for all the recruited women at the first visit of antenatal booking and individual Thyroid tests are repeated as required.Results: Following the TFT the study population is classified into pregnancies with euthyroidism‚ subclinical/ overt hypothyroidism and hyperthyroidism. The prevalence of Thyroid disorders in present study was 12.7% of which hypothyroidism noted in 10.3% (subclinical 6.9% and overt 3.4%) while hyperthyroidism seen in 2.4% (subclinical 1.8% and overt 0.6%). The various pregnancy complications, labour and neonatal outcomes have been analyzed.Conclusions: Thyroid dysfunction in pregnancy affects the health of the mother as well as the baby. Screening for Thyroid dysfunction should be performed as part of the routine antenatal work-up for successful pregnancy outcomes.

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