Pregnant Women's Attitudes and Knowledge in Relation to Access to Serum-Alpha-Fetoprotein Test

1988 ◽  
Vol 16 (4) ◽  
pp. 197-204 ◽  
Author(s):  
Marie-Louise Sandén ◽  
Per Bjurulf

Serum-Alpha-Fetoprotein (se-AFP) screening is a controversial issue in Sweden. In some areas the test has never been offered, in others it is routinely offered to all pregnant women and there are areas where the se-AFP test has been offered but is no longer available but for very special indications. This pseudoexperimental situations was used to analyze the effects of different information environments on attitudes to and knowledge of testing procedures at the antenatal clinics, especially the se-AFP test, and anxiety of malformations. Consecutive series of pregnant women in these three areas filled in questionnaires at their first visit, in the 22nd to 24th, and the 32nd to 35th weeks of pregnancy, and after delivery. The attitudes to prenatal screening were most positive in the routine screening area and most negative in the area which previously but no longer offers the test. The level of knowledge was somewhat higher in the routine screening area at the first visit to the clinic and increased substantially, especially in the routine screening area.

1988 ◽  
Vol 16 (4) ◽  
pp. 265-271 ◽  
Author(s):  
Marie-Louise Sandén ◽  
Per Bjurulf

This study analyzes attitudes which influence women in their decisions to accept or decline a serum-Alpha-FetoProtein (se-AFP) test. The survey covers all women who have visited antenatal clinics offering the se-AFP test in a given area during a specified period. All in all, the pregnant women answered four questionnaires: three before and one after delivery. 19% of the women declined the se-AFP test. During pregnancy, the women who did not take the se-AFP test said that the reason was anxiety about the results of the test. Many of the women who took the test said that they wanted assurance that the child was healthy. This entails obvious ethical problems when the test is positive. The test-routine does not have a major influence in the decisionmaking process. A change in routines to shorten the waiting time, and a different cut-off line might influence some of the declining women to accept the test.


1981 ◽  
Vol 27 (1) ◽  
pp. 133-134 ◽  
Author(s):  
J E Haddow ◽  
E M Kloza ◽  
G J Knight ◽  
D E Smith

Abstract Maternal serum alpha-fetoprotein concentrations are influenced by maternal weight during the second trimester. Heavier pregnant women have lower median values, apparently as a result of a diluting effect of larger blood volume. This phenomenon is of clinical interest because alpha-fetoprotein concentration in a pregnant woman's serum is one of the factors considered in assessing risk of poor outcome. A revision of the reference interval for alpha-fetoprotein to take body weight into account might improve its use as a diagnostic aid, especially in heavier women.


1998 ◽  
Vol 148 (8) ◽  
pp. 719-727 ◽  
Author(s):  
B. E. Richardson ◽  
B. S. Hulka ◽  
J. L. D. Peck ◽  
C. L. Hughes ◽  
B. J. van den Berg ◽  
...  

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