Recent Developments in Manufacturing Particulate Products from Double-Emulsion Templates Using Membrane and Microfluidic Devices

2007 ◽  
pp. 121-164 ◽  
Author(s):  
Goran T. Vladisavljevi ◽  
Richard A. Williams
Life ◽  
2018 ◽  
Vol 8 (4) ◽  
pp. 53 ◽  
Author(s):  
Hironori Sugiyama ◽  
Taro Toyota

Experimental evolution in chemical models of cells could reveal the fundamental mechanisms of cells today. Various chemical cell models, water-in-oil emulsions, oil-on-water droplets, and vesicles have been constructed in order to conduct research on experimental evolution. In this review, firstly, recent studies with these candidate models are introduced and discussed with regards to the two hierarchical directions of experimental evolution (chemical evolution and evolution of a molecular self-assembly). Secondly, we suggest giant vesicles (GVs), which have diameters larger than 1 µm, as promising chemical cell models for studying experimental evolution. Thirdly, since technical difficulties still exist in conventional GV experiments, recent developments of microfluidic devices to deal with GVs are reviewed with regards to the realization of open-ended evolution in GVs. Finally, as a future perspective, we link the concept of messy chemistry to the promising, unexplored direction of experimental evolution in GVs.


2010 ◽  
Vol 31 (1) ◽  
pp. 2-16 ◽  
Author(s):  
Jinwen Zhou ◽  
Amanda Vera Ellis ◽  
Nicolas Hans Voelcker

Author(s):  
Gordon D. Hoople ◽  
David A. Rolfe ◽  
Katherine C. McKinstry ◽  
Joanna R. Noble ◽  
David A. Dornfeld ◽  
...  

Recent developments in microfluidics have opened up new interest in rapid prototyping with features on the microscale. Microfluidic devices are traditionally fabricated using photolithography, however this process can be time consuming and challenging. Laser ablation has emerged as the preferred solution for rapid prototyping of these devices. This paper explores the state of rapid prototyping for microfluidic devices by comparing laser ablation to micromilling and 3D printing. A microfluidic sample part was fabricated using these three methods. Accuracy of the features and surface roughness were measured using a surface profilometer, scanning electron microscope, and optical microscope. Micromilling was found to produce the most accurate features and best surface finish down to ∼100 μm, however it did not achieve the small feature sizes produced by laser ablation. 3D printed parts, though easily manufactured, were inadequate for most microfluidics applications. While laser ablation created somewhat rough and erratic channels, the process was within typical dimensions for microfluidic channels and should remain the default for microfluidic rapid prototyping.


2014 ◽  
Vol 87 (1) ◽  
pp. 19-41 ◽  
Author(s):  
David M. Cate ◽  
Jaclyn A. Adkins ◽  
Jaruwan Mettakoonpitak ◽  
Charles S. Henry

Lab on a Chip ◽  
2020 ◽  
Vol 20 (1) ◽  
pp. 147-154 ◽  
Author(s):  
Saraf Nawar ◽  
Joshuah K. Stolaroff ◽  
Congwang Ye ◽  
Huayin Wu ◽  
Du Thai Nguyen ◽  
...  

We present a multilayer dropmaker geometry that enables the modular fabrication of microfluidic devices containing precisely patterned channel surface wettability. The platform is used for the scalable production of uniform double emulsion drops.


RSC Advances ◽  
2016 ◽  
Vol 6 (31) ◽  
pp. 25927-25933 ◽  
Author(s):  
Shunbo Li ◽  
Xiuqing Gong ◽  
Ciara S. Mc Nally ◽  
Muling Zeng ◽  
Thembaninkosi Gaule ◽  
...  

This article presents a simple and highly reliable method for preparing PDMS microfluidic double emulsion devices that employs a single-step oxidative plasma treatment to both pattern the wettability of the microchannels and to bond the chips.


2015 ◽  
Vol 450 ◽  
pp. 279-287 ◽  
Author(s):  
Seyed Ali Nabavi ◽  
Sai Gu ◽  
Goran T. Vladisavljević ◽  
Ekanem E. Ekanem

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