Carbon monoxide transfer factor: single breath method

2014 ◽  
pp. 53-78
1977 ◽  
Vol 53 (3) ◽  
pp. 271-276 ◽  
Author(s):  
J. A. Milne ◽  
R. J. Mills ◽  
J. R. T. Coutts ◽  
M. C. Macnaughton ◽  
F. Moran ◽  
...  

1. The pulmonary transfer factor for carbon monoxide was measured by the single-breath method in 21 pregnant women with no previous history of cardiac or respiratory disease. Measurements were made at monthly intervals throughout pregnancy and once post partum. 2. The transfer factor was higher in the first trimester of pregnancy than in the non-pregnant state. There was a fall in the transfer factor during pregnancy until 26 weeks gestation, after which no further decrease was observed. 3. The changes in transfer factor were not explained by alterations in haemoglobin concentration or alveolar volume. 4. Simultaneous serial estimations of plasma 17β-oestradiol were performed in all the subjects. There was no obvious direct relation between changes in the concentration of this hormone and transfer factor measurements.


1988 ◽  
Vol 138 (4) ◽  
pp. 1084-1085 ◽  
Author(s):  
Robert O. Crapo ◽  
Reed M. Gardner ◽  
Steven L. Berlin

Author(s):  
Iker García ◽  
Franchek Drobnic ◽  
Victoria Pons ◽  
Ginés Viscor

AbstractArtistic swimmers (AS) are exposed to repeated apnoeas in the aquatic environment during high intensity exercise provoking specific physiological responses to training, apnoea, and immersion. This study aimed to evaluate the changes in lung diffusing capacity in AS pre-, mid- and post-training in a combined session of apnoeic swimming, figures and choreography. Eleven elite female AS from the Spanish national team were the study’s participants. The single-breath method was used to measure lung diffusing capacity for carbon monoxide (DLCO) and one-way repeated measures ANOVA was utilized to evaluate the statistical analysis. Basal values of DLCO were higher than normal for their age and height (33.6±4.9 mL·min−1·mmHg−1; 139±19%) and there were a significant interaction between DLCO and AS training (ŋ2 p=0.547). After the apnoeic swimming (mid-training) there was an increase in DLCO from basal to 36.7±7.3 mL·min−1·mmHg−1 (p=0.021), and after the figures and choreography (post-training) there was a decrease compared to mid-training (32.3±4.6 mL·min−1·mmHg−1, p=0.013). Lung diffusing capacity changes occur during AS training, including a large increase after apnoeic swimming. There were no differences in lung diffusing capacity from pre- to post-training, although large inter-individual variability was observed.


1998 ◽  
Vol 92 (4) ◽  
pp. 628-632 ◽  
Author(s):  
R. Carter ◽  
A. Al-Rawas ◽  
R.D. Stevenson ◽  
S.K. Naik ◽  
D.J. Wheatley

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