Trials of CRT in Atrial Fibrillation and Atrial Rhythm Management Issues

2009 ◽  
pp. 277-289 ◽  
Author(s):  
Maurizio Gasparini ◽  
Franois Regoli
Keyword(s):  
Atrial Fibrillation ◽  
Management Issues ◽  
Atrial Rhythm

scholarly journals Atrial fibrillation risk loci interact to modulate Ca2+-dependent atrial rhythm homeostasis

2019 ◽  
Vol 129 (11) ◽  
pp. 4937-4950 ◽  
Author(s):  
Brigitte Laforest ◽  
Wenli Dai ◽  
Leonid Tyan ◽  
Sonja Lazarevic ◽  
Kaitlyn M. Shen ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Atrial Rhythm

Troubleshooting ICDs

2018 ◽  
pp. 245-284
Author(s):  
Timothy Betts ◽  
Julian Ormerod
Keyword(s):  
Atrial Fibrillation ◽  
Diagnosis And Treatment ◽  
Battery Life ◽  
Implantable Cardioverter Defibrillators ◽  
Common Presentation ◽  
Problem Diagnosis ◽  
Life Problems ◽  
Cardioverter Defibrillators ◽  
Management Issues

This chapter covers the causes of inappropriate implantable cardioverter defibrillators (ICD) therapies, and then covers each response in detail. Breaking down the response by key information required, and the most common presentation of each problem, diagnosis and treatment are discussed in turn. The chapter covers tachycardias (atrial, supraventricular, ventricular, etc.), atrial fibrillation or flutter, committed shocks, undersensing, and oversensing. Mechanical issues that may occur at follow up, such as lead damage or battery life problems, are covered. Finally, problems to date and management issues are described.

scholarly journals Chronic atrial fibrillation in patients with paroxysmal atrial fibrillation, atrioventricular node ablation and pacemakers

EP Europace ◽  
1999 ◽  
Vol 1 (1) ◽  
pp. 30-34 ◽  
Author(s):  
J. M. McComb ◽  
G. M. Gribbin
Keyword(s):  
Atrial Fibrillation ◽  
Multivariate Analysis ◽  
Pacemaker Implantation ◽  
Atrioventricular Node ◽  
Chronic Atrial Fibrillation ◽  
Atrial Arrhythmias ◽  
Av Node ◽  
Surface Ecg ◽  
History Of ◽  
Atrial Rhythm

Abstract Aims This study examined the factors associated with the development of chronic (or permanent) atrial fibrillation (AF) in patients who had undergone atrioventricular (AV) node ablation with permanent pacing because of paroxysmal AF. Methods A retrospective review of case notes of all 65 consecutive patients identified as having had paroxysmal atrial arrhythmias, AV node ablation and permanent pacemaker implantation was performed. Atrial rhythm was established from all pacing records and from the surface ECG. Treatment with anti-arrhythmic drugs and with warfarin was recorded. A multivariate analysis was undertaken, using atrial rhythm on final ECG and chronic AF as outcome measures. Results During a mean follow-up of 30 months, 42% of patients with paroxysmal AF had developed chronic AF. Multivariate analysis showed that increasing age, history of electrical cardioversion and VVI pacing all contributed to the development of chronic AF. 25/62 patients were taking warfarin, and four had had strokes (2·5%/year). Conclusions The majority of patients with paroxysmal atrial arrhythmias treated with AV node ablation and pacing develop chronic AF eventually. Stroke remains a risk, particularly in those who develop chronic AF.

Decrease of the atrial fibrillatory rate, increased organization of the atrial rhythm and termination of atrial fibrillation by AZD7009

2013 ◽  
Vol 46 (1) ◽  
pp. 29-35 ◽  
Author(s):  
Maria Aunes-Jansson ◽  
Nils Edvardsson ◽  
Martin Stridh ◽  
Leif Sörnmo ◽  
Lars Frison ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Atrial Rhythm

Tedisamil in Coronary Disease: Additional Benefits in the Therapy of Atrial Fibrillation?

2003 ◽  
Vol 8 (1_suppl) ◽  
pp. S33-S37 ◽  
Author(s):  
Lionel H. Opie
Keyword(s):  
Atrial Fibrillation ◽  
Ventricular Hypertrophy ◽  
Oxygen Demand ◽  
Outward Current ◽  
Left Ventricular ◽  
Ventricular Rate ◽  
Transient Outward Current ◽  
Atrial Remodeling ◽  
Atrial Rhythm ◽  
The Ideal

Atrial fibrillation has recently come into clinical and research focus. In particular, ventricular rate control has been carefully compared with atrial rhythm control. Additionally, the recent discovery of atrial stunning has initiated clinical and research interest in atrial remodeling. Atrial fibrillation is more likely to occur when the atria are damaged by increased fibrosis. The ideal way to prevent atrial fibrillation and the risk of repetition is by tackling the root causes, such as ischemic heart disease, heart failure, and left ventricular hypertrophy. Tedisamil is an unusual antifibrillatory compound that has a novel mechanism of action by inhibiting the transient outward current (Ito) and the repolarizing potassium currents in the sinoatrial node. Tedisamil works acutely against atrial fibrillation. Importantly, atrial fibrillation is often caused by or related to cardiac ischemia, and conversely, ischemia is caused by the increased oxygen demand of atrial fibrillation. Hence, the double properties of tedisamil as a drug that both inhibits atrial fibrillation and acts in an anti-ischemic mode are an attractive basis for future clinical research.

P3746Temporal patterns of premature atrial contractions predict atrial fibrillation occurrence in bradycardia patients continuously monitored through pacemaker diagnostics

2019 ◽  
Vol 40 (Supplement_1) ◽  
Author(s):  
G Boriani ◽  
G L Botto ◽  
P Pieragnoli ◽  
R P Ricci ◽  
M Biffi ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Continuous Monitoring ◽  
Cox Model ◽  
National Registry ◽  
Relative Increase ◽  
Adverse Outcomes ◽  
Temporal Occurrence ◽  
Observation Period ◽  
Atrial Rhythm

Abstract Background The frequency of premature atrial complexes (PACs) has been indirectly related with atrial fibrillation (AF) occurrence and adverse outcomes. Objective To evaluate whether temporal patterns of PACs are directly associated with AF onset in pacemaker patients with continuous monitoring of the atrial rhythm. Methods Overall, 193 pacemaker patients (49% female, 72±9 years old), enrolled in a national registry, were analyzed. Frequency of daily PACs was measured in a 14-day initial observation period, during which patients were in sinus rhythm. In the following period, temporal occurrence and frequency of daily PACs and eventual onset of AF were derived by pacemaker diagnostics. Results In the run-in period, median PACs frequency was 614 PACs/day (interquartile range=70–3056). Subsequently, in a median follow-up of 6 months, AF occurred in 109 patients, in particular in 37/96 (38.5%) patients with a PAC rate<614 PACs/day and in 72/97 (74.2%) patients with PAC rate≥614 PACs/day (p<0.001). In patients with AF occurrence, the number of daily PACs, normalized by dividing for the average of PACs in 10 preceding days, progressively increased in the 5–6 days preceding AF (Figure). Cox Model predictive analysis showed that the risk of AF was significantly higher in patients with a relative increase of the daily PACs higher than 30% compared with PACs average number in 10 preceding days (hazard ratio (95% confidence interval) = 3.67 (2.40–5.59), p<0.001). PACs changes daily trend before AF Conclusion PACs frequency increases in the 5–6 days preceding AF onset. A relative increase of the daily PACs is significantly associated with the risk of AF occurrence.

In reply: Atrial fibrillation management: Issues of concern (April 2011)

2011 ◽  
Vol 78 (11) ◽  
pp. 720.2-721
Author(s):  
Thomas Callahan ◽  
Brian Baranowski
Keyword(s):  
Atrial Fibrillation ◽  
Management Issues
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