scholarly journals Selenium Nanoparticles for Biomedical Applications: From Development and Characterization to Therapeutics

2021 ◽  
pp. 2100598
Author(s):  
Cláudio Ferro ◽  
Helena F. Florindo ◽  
Hélder A. Santos
Keyword(s):  
Biomedical Applications ◽  
Selenium Nanoparticles

Assessment of Antimicrobial Features of Selenium Nanoparticles (SeNPs) Using Cyclic Voltammetric Strategy

2019 ◽  
Vol 19 (11) ◽  
pp. 7363-7368 ◽  
Author(s):  
Madiha Saeed ◽  
M. Tayyab Ansari ◽  
Imdad Kaleem ◽  
Sadia Zafar Bajwa ◽  
Asma Rehman ◽  
...  
Keyword(s):  
Cyclic Voltammetry ◽  
Biomedical Applications ◽  
Selenium Nanoparticles ◽  
Size Distributions ◽  
Cyclic Voltammetric ◽  
Microwave Assisted ◽  
Straightforward Method ◽  
Microwave Assisted Method ◽  
Controllable Size ◽  
Cyclic Voltammetry Data

The emerging biomedical applications of selenium nanoparticles (SeNPs) require facile and efficient strategy to assess its interactions with cell membrane. In this study, an efficient and reproducible microwave assisted method was used to synthesize SeNPs with controllable size distributions. The physical properties of the emergent structures, such as morphology, structure, and size were studied. The antimicrobial applications of SeNPs were assessed by electrochemical analyses that entailed the systematic acquisition of cyclic voltammetry data. Our results demonstrate a straightforward method to predict the integrity of bacterial cell membranes following the administration of SeNP treatments.

scholarly journals Synthesis and Characterization of Selenium Nanoparticles-Lysozyme Nanohybrid System with Synergistic Antibacterial Properties

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Mahsa Vahdati ◽  
Tahereh Tohidi Moghadam
Keyword(s):  
Antibacterial Activity ◽  
Bacterial Growth ◽  
Biomedical Applications ◽  
Antibacterial Properties ◽  
Complex Form ◽  
Vital Role ◽  
Selenium Nanoparticles ◽  
Low Concentrations ◽  
Very High

AbstractIn the light of promising potency of selenium nanoparticles in biomedical applications, this is the first study to report the synergistic antibacterial activity of these nanoparticles and lysozyme. The nanohybrid system was prepared with various concentrations of each component. Resistance of Escherichia coli and Staphylococcus aureus was compared in the presence of individual Nano and Bio counterparts as well as the nanohybrid system. Upon interaction of SeNPs with Lysozyme, the nanohybrid system efficiently enhanced the antibacterial activity compared to the protein. Therefore, SeNPs play an important role in inhibition of bacterial growth at very low concentrations of protein; whereas very high amount of the protein is required to inhibit bacterial growth individually. On the other hand, lysozyme has also played a vital role in antibacterial property of SeNPs, inducing 100% inhibition at very low concentration of each component. Hence, presence of both nano and bio counterparts induced vital interplay in the Nanohybrid system. The aged samples also presented good stability of SeNPs both as the intact and complex form. Results of this effort highlight design of nanohybrid systems with synergistic antibacterial properties to overcome the emerging antibiotic resistance as well as to define fruitful applications in biomedicine and food safety.

Potentialities of selenium nanoparticles in biomedical science

2021 ◽  
Vol 45 (6) ◽  
pp. 2849-2878
Author(s):  
Vanya Nayak ◽  
Kshitij RB Singh ◽  
Ajaya Kumar Singh ◽  
Ravindra Pratap Singh
Keyword(s):  
Biomedical Applications ◽  
Selenium Nanoparticles ◽  
Biomedical Science ◽  
Biomedical Domain

Selenium nanoparticles (SeNPs) have revolutionized biomedical domain and are still developing rapidly. Hence, this perspective elaborates SeNPs properties, synthesis, and biomedical applications, together with their potential for management of SARS-CoV-2.

scholarly journals Selenium Nanoparticles: A Review on Synthesis and Biomedical Applications

2022 ◽  
Author(s):  
Pawan Kumar Khanna ◽  
Neha Bisht ◽  
Priyanka Phalswal
Keyword(s):  
Biomedical Applications ◽  
Selenium Nanoparticles

Selenium is a trace and essential micronutrient for the health of human, animals, and microorganisms. Recently, selenium nanoparticles (SeNPs) attracted many researchers’ interest due to their biocompatibility, bioavailability, and low...

Surface Functionalized Selenium Nanoparticles for Biomedical Applications

2014 ◽  
Vol 10 (10) ◽  
pp. 3004-3042 ◽  
Author(s):  
Savita Chaudhary ◽  
Ahmad Umar ◽  
S. K. Mehta
Keyword(s):  
Biomedical Applications ◽  
Selenium Nanoparticles

Applications of Scanning Microscopy in Biomedical Research

1968 ◽  
Vol 26 ◽  
pp. 354-355
Author(s):  
T. L. Hayes
Keyword(s):  
Information Content ◽  
Biomedical Research ◽  
Biomedical Applications ◽  
Three Dimensional ◽  
Dental Enamel ◽  
Resolving Power ◽  
Whole Mount ◽  
Two Parameters ◽  
Content Information ◽  
Sectioned Tissue

Biomedical applications of the scanning electron microscope (SEM) have increased in number quite rapidly over the last several years. Studies have been made of cells, whole mount tissue, sectioned tissue, particles, human chromosomes, microorganisms, dental enamel and skeletal material. Many of the advantages of using this instrument for such investigations come from its ability to produce images that are high in information content. Information about the chemical make-up of the specimen, its electrical properties and its three dimensional architecture all may be represented in such images. Since the biological system is distinctive in its chemistry and often spatially scaled to the resolving power of the SEM, these images are particularly useful in biomedical research.In any form of microscopy there are two parameters that together determine the usefulness of the image. One parameter is the size of the volume being studied or resolving power of the instrument and the other is the amount of information about this volume that is displayed in the image. Both parameters are important in describing the performance of a microscope. The light microscope image, for example, is rich in information content (chemical, spatial, living specimen, etc.) but is very limited in resolving power.

How SIMS microscopy can be used in medicine

1992 ◽  
Vol 50 (2) ◽  
pp. 1602-1603
Author(s):  
Philippe Fragu
Keyword(s):  
Mass Spectrometry ◽  
Biomedical Applications ◽  
Secondary Ion Mass Spectrometry ◽  
Chemical Elements ◽  
Biological Applications ◽  
The Past ◽  
Potential Source ◽  
Secondary Ion ◽  
Chemical Integrity ◽  
Scientific Endeavour

The identification, localization and quantification of intracellular chemical elements is an area of scientific endeavour which has not ceased to develop over the past 30 years. Secondary Ion Mass Spectrometry (SIMS) microscopy is widely used for elemental localization problems in geochemistry, metallurgy and electronics. Although the first commercial instruments were available in 1968, biological applications have been gradual as investigators have systematically examined the potential source of artefacts inherent in the method and sought to develop strategies for the analysis of soft biological material with a lateral resolution equivalent to that of the light microscope. In 1992, the prospects offered by this technique are even more encouraging as prototypes of new ion probes appear capable of achieving the ultimate goal, namely the quantitative analysis of micron and submicron regions. The purpose of this review is to underline the requirements for biomedical applications of SIMS microscopy.Sample preparation methodology should preserve both the structural and the chemical integrity of the tissue.

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