Nanocatalytic Theranostics with Glutathione Depletion and Enhanced Reactive Oxygen Species Generation for Efficient Cancer Therapy

2021 ◽  
pp. 2006892
Author(s):  
Lian‐Hua Fu ◽  
Yilin Wan ◽  
Chao Qi ◽  
Jin He ◽  
Chunying Li ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Cancer Therapy ◽  
Reactive Oxygen Species Generation ◽  
Reactive Oxygen ◽  
Glutathione Depletion ◽  
Oxygen Species

scholarly journals Ultrasound-induced reactive oxygen species generation and mitochondria-specific damage by sonodynamic agent/metal ion-doped mesoporous silica

RSC Advances ◽  
2019 ◽  
Vol 9 (68) ◽  
pp. 39924-39931 ◽  
Author(s):  
Kecan Lin ◽  
Ziguo Lin ◽  
Yujie Li ◽  
Youshi Zheng ◽  
Da Zhang
Keyword(s):  
Reactive Oxygen Species ◽  
Tumor Microenvironment ◽  
Cancer Therapy ◽  
Mesoporous Silica ◽  
Metal Ion ◽  
Reactive Oxygen Species Generation ◽  
Reactive Oxygen ◽  
Oxygen Species

Herein, we design tumor microenvironment specific active nano sono-chemodynamic agent for synergistic photodynamic–chemodynamic cancer therapy.

Methylmercury cytotoxicity in PC12 cells is mediated by primary glutathione depletion independent of excess reactive oxygen species generation

Toxicology ◽  
2004 ◽  
Vol 204 (2-3) ◽  
pp. 175-185 ◽  
Author(s):  
Rita Gatti ◽  
Silvana Belletti ◽  
Jacopo Uggeri ◽  
Maria Vittoria Vettori ◽  
Antonio Mutti ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Pc12 Cells ◽  
Reactive Oxygen Species Generation ◽  
Reactive Oxygen ◽  
Glutathione Depletion ◽  
Oxygen Species ◽  
Excess Reactive Oxygen Species

Peroxidase-like Fe3O4 nanocomposite for activatable reactive oxygen species generation and cancer theranostics

2018 ◽  
Vol 2 (6) ◽  
pp. 1184-1194 ◽  
Author(s):  
Kai Zhang ◽  
Zhou Yang ◽  
Xiangdan Meng ◽  
Yu Cao ◽  
Yuedong Zhang ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Photodynamic Therapy ◽  
Cancer Therapy ◽  
Reactive Oxygen Species Generation ◽  
Reactive Oxygen ◽  
Oxygen Species ◽  
Cancer Theranostics

Photodynamic therapy (PDT) that utilizes apoptosis induced by reactive oxygen species (ROS) has received extensive attention for use in practical cancer therapy.

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