scholarly journals Improvement of cognitive function after paper‐based cognitive training intervention in early‐stage Alzheimer's disease

2020 ◽  
Vol 16 (S6) ◽  
Author(s):  
Jeong Ho Han ◽  
Min Ju Kang
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cognitive Function ◽  
Cognitive Training ◽  
Early Stage ◽  
Training Intervention

A Review of Computer-Based Cognitive Training for Individuals With Mild Cognitive Impairment and Alzheimer's Disease

2016 ◽  
Vol 1 (2) ◽  
pp. 47-61 ◽  
Author(s):  
Kimberly D. Mueller
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Cognitive Function ◽  
Cognitive Training ◽  
Training Programs ◽  
Early Stage ◽  
Significant Evidence ◽  
Computer Based

Computer-based cognitive training programs are increasing in popularity, not only due to trends in technological advances, but also due to the intense marketing campaigns of such programs toward late-middle-aged and older adults. This article's objective is to evaluate the effectiveness of computer-based cognitive training programs in maintaining or improving cognitive function in people with mild cognitive impairment (MCI) and early-stage Alzheimer's disease (AD). Twelve databases were searched using terms related to computerized cognitive training (CCT) and MCI and Alzheimer's disease (AD). Two raters independently extracted articles using agreed-upon criteria. Due to the heterogeneity of the samples, interventions, and outcomes, data of the studies was not statistically pooled for meta-analysis. Ten studies met the inclusion criteria and the findings were summarized. All of the studies reviewed provided support that computerized cognitive interventions are feasible in people with MCI or early-stage AD. None of the studies yielded significant evidence to support the use of CCT alone for improvement or maintenance of cognitive function in people with MCI or AD. Further, no studies presented significant evidence of transfer of training to everyday skills and tasks. Recommendations for evaluating products and for areas of research need are provided.

Cognitive Training for Early-Stage Alzheimer’s Disease and Dementia

2009 ◽  
Vol 35 (3) ◽  
pp. 23-29 ◽  
Author(s):  
Fang Yu ◽  
Karen M. Rose ◽  
Sandra C. Burgener ◽  
Cindy Cunningham ◽  
Linda L. Buettner ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cognitive Training ◽  
Early Stage

scholarly journals Adaptive working memory strategy training in early Alzheimer's disease: Randomised controlled trial

2017 ◽  
Vol 210 (1) ◽  
pp. 61-66 ◽  
Author(s):  
J. D. Huntley ◽  
A. Hampshire ◽  
D. Bor ◽  
A. Owen ◽  
R. J. Howard
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Working Memory ◽  
Cognitive Function ◽  
Cognitive Training ◽  
Controlled Trial ◽  
Verbal Working Memory ◽  
Strategy Training ◽  
Post Intervention ◽  
Early Alzheimer’S Disease

BackgroundInterventions that improve cognitive function in Alzheimer's disease are urgently required.AimsTo assess whether a novel cognitive training paradigm based on ‘chunking’ improves working memory and general cognitive function, and is associated with reorganisation of functional activity in prefrontal and parietal cortices (trial registration: ISRCTN43007027).MethodThirty patients with mild Alzheimer's disease were randomly allocated to receive 18 sessions of 30 min of either adaptive chunking training or an active control intervention over approximately 8 weeks. Pre- and post-intervention functional magnetic resonance imaging (fMRI) scans were also conducted.ResultsAdaptive chunking training led to significant improvements in verbal working memory and untrained clinical measures of general cognitive function. Further, fMRI revealed a bilateral reduction in task-related lateral prefrontal and parietal cortex activation in the training group compared with controls.ConclusionsChunking-based cognitive training is a simple and potentially scalable intervention to improve cognitive function in early Alzheimer's disease.

scholarly journals Everyday cognition scales are related to cognitive function in the early stage of probable Alzheimer’s disease and FDG-PET findings

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Jung-Lung Hsu ◽  
Wen-Chuin Hsu ◽  
Chiung-Chih Chang ◽  
Kun-Ju Lin ◽  
Ing-Tsung Hsiao ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cognitive Function ◽  
Fdg Pet ◽  
Early Stage ◽  
Everyday Cognition

Development and validation of Cognitive Training Intervention for Alzheimer’s disease (CTI-AD): A picture-based interventional program

Dementia ◽  
2018 ◽  
Vol 19 (4) ◽  
pp. 1203-1219
Author(s):  
Swati Bajpai ◽  
Manjari Tripathi ◽  
RM Pandey ◽  
A.B Dey ◽  
Ashima Nehra
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cognitive Training ◽  
Pharmacological Therapy ◽  
Training Intervention ◽  
Group Discussions ◽  
Training Interventions ◽  
Early Alzheimer’S Disease ◽  
Development And Validation ◽  
Progressive Disorder

Introduction Alzheimer’s disease is a gradual and progressive disorder which cripples the person’s functionality due to cognitive decline. Many clinicopathological and pharmacological therapy has the potential to slow down the progression of the disease but has limited efficacy. One complimentary approach that has emerged is cognitive training interventions which have shown synergistic effect with the drug therapy. Nevertheless, many cognitive interventions lack on specificities of the intervention due to which its efficacy gets scrutinized. Objective To describe the foundation, content, and development of Cognitive Training Intervention for Alzheimer’s disease (CTI-AD) along with the treatment feasibility based on a pilot study. Materials and methods A culture-specific picture-based eight weeks cognitive training manual was developed based on extensive review and focused group discussions. It was standardized on 63 older participants (48 healthy controls (HC); 15 early Alzheimer’s disease cases). Results All the tasks were progressive in nature and were found effective in discriminating the cognitive performance of early Alzheimer’s disease and HC throughout the intervention period. Moreover, it also improved early Alzheimer’s disease performance on the memory (HC: 1st week/8th week = 21.6 ± 5.7/57.3 ± 19.0; early Alzheimer’s disease: 1st week/8th week = 48.5 ± 22.9/60.5 ± 21.8); attention (HC: 1st week/8th week = 90.2 ± 18.0/196.9 ± 28.0; early Alzheimer’s disease: 1st week/8th week = 216.6 ± 78.2/286.8 ± 87.0) and language (HC: 1st week/8th week = 29.8 ± 9.4/115.3 ± 31.1; early Alzheimer’s disease: 1st week/8th week = 211.8 ± 68.4/270.4 ± 104.9) domains, respectively, from the baseline level. Conclusion The current manual (CTI-AD) is one of the first promising non-pharmacological program developed nationally with a strong theoretical base to cater to the tertiary needs of the older adults with early Alzheimer’s disease.

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