Demographics and clinical risk factor(s) variations in mortality of Alzheimer's disease in Taiwan: A 15‐year national population‐based study

Abstract Introduction There is a paucity of data on the prevalence and correlates of Alzheimer’s disease and related dementias in sub-Saharan Africa.Objective To estimate the prevalence and correlates of Alzheimer’s disease and related dementias in rural Uganda.Methods We conducted a cross-sectional, population-based study in a rural region of southwestern Uganda. The Brief Community Screening Instrument for Dementia was administered to a multi-stage area probability sample of 400 people aged 60 years and over. Multivariable logistic regression was used to estimate correlates of probable dementia.Results Overall, 80 (20%) of the sample screened positive for dementia. On multivariable regression, we estimated the following correlates of probable dementia: age (adjusted odds ratio [AOR], 1.02 per year; 95% confidence interval [CI], 1.10-1.03, p˂0.001), having some education (AOR, 0.57; 95% CI, 0.41-0.81, p=0.001), exercise (AOR, 0.44; 95% CI, 0.27-0.72, p=0.001), and having a ventilated kitchen (AOR, 0.43; (95% CI, 0.24-0.77, p=0.001).Conclusion In this population-based sample of older-age adults, nearly one-fifth screened positive for dementia.

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Urate and risk of Alzheimer's disease and vascular dementia: A population-based study

Alzheimer s & Dementia ◽

10.1016/j.jalz.2019.01.014 ◽

2019 ◽

Vol 15 (6) ◽

pp. 754-763 ◽

Cited By ~ 5

Author(s):

Lieke E.J.M. Scheepers ◽

Lennart T.H. Jacobsson ◽

Silke Kern ◽

Lena Johansson ◽

Mats Dehlin ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Vascular Dementia ◽

Population Based ◽

Population Based Study

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Population-based study of the prevalence and presentation of dementia in adults with Down's syndrome

The British Journal of Psychiatry ◽

10.1192/bjp.172.6.493 ◽

1998 ◽

Vol 172 (6) ◽

pp. 493-498 ◽

Cited By ~ 172

Author(s):

Anthony J. Holland ◽

Johnny Hon ◽

Felicia A. Huppert ◽

Fran Stevens ◽

Peter Watson

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Down's Syndrome ◽

Down’S Syndrome ◽

The Elderly ◽

Population Based ◽

Prevalence Rates ◽

Population Based Study ◽

Age Related ◽

Living Skills

BackgroundThe reported prevalence rates of dementia in people with Down's syndrome have varied considerably across studies. The aim of this study was to investigate the extent of clinical change with age using an established diagnostic instrument in an unbiased, population-based sample of older people with Down's syndrome.MethodChanges in memory, personality, general mental functioning and daily living skills were assessed using a modified version of the informant interview of the Cambridge Examination for Mental Disorders of the Elderly (CAMDEX).ResultsAge-specific prevalence rates of dementia varied according to the diagnostic criteria used. Using CAMDEX criteria for Alzheimer's disease, prevalence rates increased from 3.4 to 10.3 to 40% in the 30–39, 40–49 and 50–59 age group, respectively.ConclusionsOverall, the age-related pattern of presentation and dementia diagnoses differs from that seen in the general elderly population. However, age-specific prevalence rates of Alzheimer's disease were similar but 30–40 years earlier in life.

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