scholarly journals Animal fluency improvements and confrontation naming declines over 6 months are associated with differential conversion from MCI to AD in ADNI

2021 ◽  
Vol 17 (S6) ◽  
Author(s):  
Nancy S. Foldi ◽  
Douglas Tommet ◽  
Laura Rabin ◽  
Melissa Lamar ◽  
Richard N Jones ◽  
...  
Keyword(s):  
1987 ◽  
Vol 18 (3) ◽  
pp. 206-216 ◽  
Author(s):  
Melanie Fried-Oken

A new procedure entitled the Double Administration Naming Technique is proposed to assist the clinician in obtaining qualitative information about a client's visual confrontation naming skills. It involves the administration of the standard naming test followed by a readministration of the instrument. A series of naming cues then are presented. By examining the number and types of naming errors produced during the two test presentations, the clinician distinguishes word-finding problems from expressive vocabulary limitations and qualitatively describes the language disorder. The cues that facilitate correct naming are used to plan effective treatment goals.


2019 ◽  
Vol 62 (12) ◽  
pp. 4464-4482 ◽  
Author(s):  
Diane L. Kendall ◽  
Megan Oelke Moldestad ◽  
Wesley Allen ◽  
Janaki Torrence ◽  
Stephen E. Nadeau

Purpose The ultimate goal of anomia treatment should be to achieve gains in exemplars trained in the therapy session, as well as generalization to untrained exemplars and contexts. The purpose of this study was to test the efficacy of phonomotor treatment, a treatment focusing on enhancement of phonological sequence knowledge, against semantic feature analysis (SFA), a lexical-semantic therapy that focuses on enhancement of semantic knowledge and is well known and commonly used to treat anomia in aphasia. Method In a between-groups randomized controlled trial, 58 persons with aphasia characterized by anomia and phonological dysfunction were randomized to receive 56–60 hr of intensively delivered treatment over 6 weeks with testing pretreatment, posttreatment, and 3 months posttreatment termination. Results There was no significant between-groups difference on the primary outcome measure (untrained nouns phonologically and semantically unrelated to each treatment) at 3 months posttreatment. Significant within-group immediately posttreatment acquisition effects for confrontation naming and response latency were observed for both groups. Treatment-specific generalization effects for confrontation naming were observed for both groups immediately and 3 months posttreatment; a significant decrease in response latency was observed at both time points for the SFA group only. Finally, significant within-group differences on the Comprehensive Aphasia Test–Disability Questionnaire ( Swinburn, Porter, & Howard, 2004 ) were observed both immediately and 3 months posttreatment for the SFA group, and significant within-group differences on the Functional Outcome Questionnaire ( Glueckauf et al., 2003 ) were found for both treatment groups 3 months posttreatment. Discussion Our results are consistent with those of prior studies that have shown that SFA treatment and phonomotor treatment generalize to untrained words that share features (semantic or phonological sequence, respectively) with the training set. However, they show that there is no significant generalization to untrained words that do not share semantic features or phonological sequence features.


1997 ◽  
Vol 30 (1) ◽  
pp. 11-22 ◽  
Author(s):  
Gérard Deloche ◽  
Didier Hannequin ◽  
Monique Dordain ◽  
Marie-Noëlle Metz-Lutz ◽  
Helgard Kremin ◽  
...  
Keyword(s):  

NeuroImage ◽  
2009 ◽  
Vol 47 ◽  
pp. S91
Author(s):  
L Frings ◽  
S Abel ◽  
K Dressel ◽  
D Saur ◽  
D Kümmerer ◽  
...  

2011 ◽  
Vol 17 (4) ◽  
pp. 449-456 ◽  
Author(s):  
AM Smerbeck ◽  
J Parrish ◽  
D Serafin ◽  
EA Yeh ◽  
B Weinstock-Guttman ◽  
...  

Background: Children with multiple sclerosis (MS) can suffer significant cognitive deficits. This study investigates the sensitivity and validity in pediatric MS of two visual processing tests borrowed from the adult literature, the Brief Visuospatial Memory Test-Revised (BVMTR) and the Symbol Digit Modalities Test (SDMT). Objective: To test the hypothesis that visual processing is disproportionately impacted in pediatric MS by comparing performance with that of healthy controls on the BVMTR and SDMT. Methods: We studied 88 participants (43 MS, 45 controls) using a neuropsychological assessment battery including measures of intelligence, language, visual memory, and processing speed. Patients and demographically matched controls were compared to determine which tests are most sensitive in pediatric MS. Results: Statistically significant differences were found between the MS and control groups on BVMTR Total Learning ( t (84) = 4.04, p < 0.001, d = 0.87), BVMTR Delayed Recall ( t (84) = 4.45, p < 0.001, d = 0.96), and SDMT ( t (38) = 2.19, p = 0.035, d = 0.69). No significant differences were found between groups on confrontation naming or general intellectual ability. Validity coefficients exploring correlation between BVMTR, SDMT, and disease characteristics were consistent with the adult literature. Conclusions: This study found that BVMTR and SDMT may be useful in assessing children and adolescents with MS.


2020 ◽  
Vol 10 (8) ◽  
pp. 2984
Author(s):  
Bhagya Nathali Silva ◽  
Murad Khan ◽  
Ruchire Eranga Wijesinghe ◽  
Samantha Thelijjagoda ◽  
Kijun Han

Survivors of either a hemorrhagic or ischemic stroke tend to acquire aphasia and experience spontaneous recovery during the first six months. Nevertheless, a considerable number of patients sustain aphasia and require speech and language therapy to overcome the difficulties. As a preliminary study, this article aims to distinguish aphasia caused from a temporoparietal lesion. Typically, temporal and parietal lesions cause Wernicke’s aphasia and Anomic aphasia. Differential diagnosis between Anomic and Wernicke’s has become controversial and subjective due to the close resemblance of Wernicke’s to Anomic aphasia when recovering. Hence, this article proposes a clinical diagnosis system that incorporates normal coupling between the acoustic frequencies of speech signals and the language ability of temporoparietal aphasias to delineate classification boundary lines. The proposed inspection system is a hybrid scheme consisting of automated components, such as confrontation naming, repetition, and a manual component, such as comprehension. The study was conducted involving 30 participants clinically diagnosed with temporoparietal aphasias after a stroke and 30 participants who had experienced a stroke without aphasia. The plausibility of accurate classification of Wernicke’s and Anomic aphasia was confirmed using the distinctive acoustic frequency profiles of selected controls. Accuracy of the proposed system and algorithm was confirmed by comparing the obtained diagnosis with the conventional manual diagnosis. Though this preliminary work distinguishes between Anomic and Wernicke’s aphasia, we can claim that the developed algorithm-based inspection model could be a worthwhile solution towards objective classification of other aphasia types.


Author(s):  
Merike Lang ◽  
Mónica Rosselli ◽  
Maria T Greig ◽  
Valeria L Torres ◽  
Idaly Vélez-Uribe ◽  
...  

Abstract Objective To analyze (1) whether there are ethnic differences in the severity of depressive symptoms between groups of elders classified as cognitively normal (CN) or amnestic mild cognitive impairment (aMCI) and (2) the influence of depressive symptoms on specific cognitive performance by ethnicity across diagnoses, controlling for covariates. Methods 164 Hispanics residing in the United States (HAs) and European Americans (EAs) (100 women; Mage = 72.1, SD = 8.0) were diagnosed as either CN or aMCI. Depressive symptoms were measured with the Geriatric Depression Scale (GDS-15). Cognition was assessed using the Loewenstein-Acevedo Scales for Semantic Interference and Learning (semantic memory), Multilingual Naming Test (confrontation naming), and the Stroop Test (Color–Word condition; executive function). A 2 × 2 univariate ANCOVA as well as linear and logistic regressions explored differences in depressive symptoms among diagnostic and ethnic groups. Results Higher depression was seen in aMCI compared to the CN group for both ethnicities, after controlling for age, education, gender, and Mini-Mental State Examination score. Greater levels of depression also predicted lower scores in confrontation naming and semantic memory for only the EA group and marginally in scores of executive function for HA participants. GDS-15 scores of ≤ 4 also predicted less likelihood of aMCI diagnosis. Conclusions Severity of depressive symptoms was associated with greater cognitive impairment, independent of ethnicity. Significant results suggest detrimental effects of depression on clinical diagnoses most evidently for subjects from the EA group.


2018 ◽  
Vol 53 (1) ◽  
pp. 13 ◽  
Author(s):  
Yael Neumann ◽  
Amy Vogel-Eyny ◽  
Dalia Cahana-Amitay ◽  
Avron Spiro ◽  
JungMoon Hyun ◽  
...  

Findings regarding the relation between naming and inhibition among older adults is limited. We posited inhibitory control is crucial for successful naming and tested its role in older adults by exaggerating its effects. Participants included 215 older adults aged 55-89 years, categorized as “good” or ”poor” namers, based on confrontation naming scores. Via a computerized speeded picture-naming test (SNT), we induced intrusions. We then determined the distance between the source for the intruding word and the current item. Performance on traditional neuropsychological tests of inhibition was also assessed. Results revealed that poorer namers had more intrusions on the SNT than better namers, and their intrusions lingered through more stimuli. This suggests that poorer namers experienced greater retrieval inhibition difficulties than better namers. Performance on neuropsychological tests of inhibition also discriminated between better and poorer namers. In conclusion, successful naming among older adults appears to rely heavily on maintaining inhibitory abilities.***Efeitos da inibição na nomeação no envelhecimento***Os achados sobre a relação entre nomeação e inibição entre os idosos são limitados. Nós postulamos que o controle inibitório é crucial para a nomeação bem-sucedida e testamos seu papel em idosos, exagerando seus efeitos. Os participantes foram 215 idosos com idades entre 55-89 anos, categorizados como "bons" ou "pobres" nomeadores, com base em pontuações de nomeação. Através de um teste computadorizado de nomeação de imagens (SNT), induzimos intrusões. Determinamos então a distância entre a fonte da palavra intrusa e o item atual. O desempenho em testes neuropsicológicos tradicionais de inibição também foi avaliado. Os resultados revelaram que os mais nomeadores “pobres” tiveram mais intrusões no SNT do que os “bons”, e suas intrusões permaneceram através de mais estímulos. Isso sugere que os nomeadores mais pobres experimentaram maiores dificuldades de inibição de recuperação do que os melhores nomeadores. O desempenho em testes neuropsicológicos de inibição também discriminou entre nomeadores melhores e mais pobres. Concluindo, a nomeação bem-sucedida entre os adultos mais velhos parece depender muito da manutenção de habilidades inibitórias.


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