An enzyme-free and label-free fluorescent biosensor for small molecules by G-quadruplex based hybridization chain reaction

Talanta ◽  
2015 ◽  
Vol 138 ◽  
pp. 15-19 ◽  
Author(s):  
Qingai Chen ◽  
Qingquan Guo ◽  
Ying Chen ◽  
Jie Pang ◽  
Fengfu Fu ◽  
...  
Keyword(s):  
Small Molecules ◽  
Hybridization Chain Reaction ◽  
Label Free ◽  
Chain Reaction ◽  
Fluorescent Biosensor ◽  
G Quadruplex

Label-free and enzyme-free detection of microRNA based on a hybridization chain reaction with hemin/G-quadruplex enzymatic catalysis-induced MoS2 quantum dots via the inner filter effect

Nanoscale ◽  
2020 ◽  
Vol 12 (2) ◽  
pp. 808-814 ◽  
Author(s):  
Jia Ge ◽  
Zhangyu Qi ◽  
Liangliang Zhang ◽  
Xueping Shen ◽  
Yanmei Shen ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Enzymatic Catalysis ◽  
Inner Filter Effect ◽  
Free Enzyme ◽  
Hybridization Chain Reaction ◽  
Label Free ◽  
Chain Reaction ◽  
Specific Strategy ◽  
Filter Effect ◽  
G Quadruplex

A new label-free, enzyme-free, and specific strategy for the assay of microRNA has been developed based on a hybridization chain reaction with hemin/G-quadruplex enzymatic catalysis-induced MoS2 quantum dots via the inner filter effect.

A label-free cyclic assembly of G-quadruplex nanowires for cascade amplification detection of T4 polynucleotide kinase activity and inhibition

The Analyst ◽  
2015 ◽  
Vol 140 (17) ◽  
pp. 6124-6130 ◽  
Author(s):  
Zhilu Shi ◽  
Xiafei Zhang ◽  
Rui Cheng ◽  
Baoxin Li ◽  
Yan Jin
Keyword(s):  
Kinase Activity ◽  
Hybridization Chain Reaction ◽  
Label Free ◽  
Chain Reaction ◽  
Polynucleotide Kinase ◽  
G Quadruplex ◽  
Amplification Strategy ◽  
Cascade Amplification ◽  
T4 Polynucleotide Kinase

A label-free and enzyme-free amplification strategy has been developed for sensitively and specifically studying PNK activity and inhibitionviathe hybridization chain reaction (HCR).

Silver nanocluster-lightened hybridization chain reaction

RSC Advances ◽  
2016 ◽  
Vol 6 (62) ◽  
pp. 57502-57506 ◽  
Author(s):  
Lin Liu ◽  
Qing Li ◽  
Li-Juan Tang ◽  
Ru-Qin Yu ◽  
Jian-Hui Jiang
Keyword(s):  
Nucleic Acid ◽  
Silver Nanoclusters ◽  
Hybridization Chain Reaction ◽  
Label Free ◽  
Chain Reaction ◽  
Silver Nanocluster ◽  
Turn On ◽  
Nucleic Acid Assays

A hybridization chain reaction (HCR) lightened by DNA-stabilized silver nanoclusters (AgNCs) as a label-free and turn on fluorescence platform for nucleic acid assays.

Lab in a tube: a fast-assembled colorimetric sensor for highly sensitive detection of oligonucleotides based on a hybridization chain reaction

RSC Advances ◽  
2015 ◽  
Vol 5 (55) ◽  
pp. 44714-44721 ◽  
Author(s):  
Siqi Zhang ◽  
Kun Wang ◽  
Zhenyu Li ◽  
Zhongmin Feng ◽  
Ting Sun
Keyword(s):  
Complex Formation ◽  
Dna Sequence ◽  
Self Assembly ◽  
The Self ◽  
Hybridization Chain Reaction ◽  
Chain Reaction ◽  
Highly Sensitive ◽  
G Quadruplex ◽  
Colored Product ◽  
Highly Sensitive Detection

Upon adding THBV, the self-assembly of THBV with H1 allows the rest of the DNA sequence of H1 to accelerate H1–H2 complex formation. The G-quadruplex at the end of the H1–H2 complex could catalyze TMB into a colored product.

Cationic-perylene-G-quadruplex complex based fluorescent biosensor for label-free detection of Pb 2+

Talanta ◽  
2016 ◽  
Vol 149 ◽  
pp. 98-102 ◽  
Author(s):  
Xu-Hua Zhao ◽  
Liang Gong ◽  
Yuan Wu ◽  
Xiao-Bing Zhang ◽  
Jun Xie
Keyword(s):  
Label Free ◽  
Fluorescent Biosensor ◽  
Label Free Detection ◽  
G Quadruplex
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