A Heme‐Acquisition Protein Reconstructed with a Cobalt 5‐Oxaporphyrinium Cation and Its Growth‐Inhibition Activity Toward Multidrug‐Resistant Pseudomonas aeruginosa

2021 ◽  
Author(s):  
Asahi Takiguchi ◽  
Erika Sakakibara ◽  
Hiroshi Sugimoto ◽  
Osami Shoji ◽  
Hiroshi Shinokubo
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Growth Inhibition ◽  
Multidrug Resistant ◽  
Inhibition Activity ◽  
Heme Acquisition ◽  
Growth Inhibition Activity

scholarly journals Evaluation of Moringa Peregrina (Forsk) Fiori, Leaf and Seed Extract Against Multidrug Resistant Strains of Bacteria and Fungus of Clinical Origin

2021 ◽  
Vol 3 (1) ◽  
pp. 20-26
Author(s):  
Suliman Mansour Albalawi ◽  
Abdulrahman K. Al-Asmari ◽  
Syed Rafatullah ◽  
Maysa Mahfoud
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Growth Inhibition ◽  
Acinetobacter Baumannii ◽  
Bacterial Resistance ◽  
Antimicrobial Agents ◽  
Colorimetric Assay ◽  
Multidrug Resistant ◽  
Klebsiella Pneumonia ◽  
Isolation And Purification ◽  
Moringa Peregrina

  The emergence of antibiotic resistant microorganism strains has become a critical concern in the treatment of infectious diseases and makes the search of an alternative therapy a must. The study was designed to evaluate the in vitro antimicrobial activities of the Moringa peregrina (MP) leave (MPL) and seed (MPS) extracts. Antimicrobial assays were performed using a microplate growth inhibition assay against 11 multidrug-resistant (MDR) strains. Following qualitative analysis, dose-response assays were performed using the MTT colorimetric assay. The results showed a strong correlation between the MPL and MPS extract concentration and growth inhibition (P<0.001). MP extract revealed a remarkable antimicrobial effect and inhibited the growth and survival of MDR pathogens which include Escherichia coli; Pseudomonas aeruginosa; Klebsiella pneumonia; Acinetobacter baumannii; Staphylococcus aureus between (88.6-94.7 %) and between (62.3- 88.7%) against Candida Kefyer; Candida parapsilosis; Candida albicans; Candida glabrata; Aspergillus flavus and Fusarium oxysporum. MIC50 ranging from ≤6.25 to 25 mg/mL. Acinetobacter baumannii and Pseudomonas aeruginosa were the most susceptible to MP extracts (MIC50 < 6.25 mg/mL). These results support the use of MP in Arab traditional medicine as natural antimicrobial agents. Additionally, the use of such naturally occurring adjuvant derived from medicinal plants can be used as an adjuvant with synthetic antibiotics to combat bacterial resistance and to enhance the antibacterial potential. Further studies are recommended on isolation and purification of novel antimicrobial molecules to treat the infections caused by microbes.  

Improved microbial growth inhibition activity of bio-surfactant induced Ag–TiO2 core shell nanoparticles

2015 ◽  
Vol 327 ◽  
pp. 504-516 ◽  
Author(s):  
D. Nithyadevi ◽  
P. Suresh Kumar ◽  
D. Mangalaraj ◽  
N. Ponpandian ◽  
C. Viswanathan ◽  
...  
Keyword(s):  
Growth Inhibition ◽  
Microbial Growth ◽  
Core Shell ◽  
Inhibition Activity ◽  
Shell Nanoparticles ◽  
Microbial Growth Inhibition ◽  
Core Shell Nanoparticles ◽  
Growth Inhibition Activity

Growth inhibition activity and bacteriophage and bacteriocinlike particles associated with different species of Clostridium

1981 ◽  
Vol 27 (2) ◽  
pp. 216-225 ◽  
Author(s):  
Beatriz M. Nieves ◽  
Francisco Gil ◽  
Francisco J. Castillo
Keyword(s):  
Growth Inhibition ◽  
Mitomycin C ◽  
The Other ◽  
Inhibition Activity ◽  
The One ◽  
Growth Inhibition Activity

Thirty-four strains corresponding to 16 species of Clostridium were examined for growth inhibition activity and production of phage and bacteriocinlike particles. Twenty-five strains were found to inhibit growth of one or more of the other strains. The widest range of activity corresponded to C. bifermentans 18137 which inhibited growth of 23 strains. Cell-free filtrates of positive cultures were inactive with the exception of the one from C. bifermentans 18137. A wide variety of particles with diverse morphology was observed in lysates of cultures treated with mitomycin C (1 μg/mL).

Design, Synthesis and Growth Inhibition Activity of Bis-Epoxyethyl Derivatives of Stallimycin Modified on the Amidino Moiety

2004 ◽  
Vol 13 (5) ◽  
pp. 282-296
Author(s):  
Romeo Romagnoli ◽  
Pier Giovanni Baraldi ◽  
Maria Giovanna Pavani ◽  
Francesca Fruttarolo ◽  
Delia Preti ◽  
...  
Keyword(s):  
Growth Inhibition ◽  
Inhibition Activity ◽  
Design Synthesis ◽  
Derivatives Of ◽  
Growth Inhibition Activity

Synthesis and growth inhibition activity of α-Bromoacrylic heterocyclic and benzoheterocyclic derivatives of distamycin A modified on the amidino moiety

2003 ◽  
Vol 11 (6) ◽  
pp. 965-975 ◽  
Author(s):  
Pier Giovanni Baraldi ◽  
Italo Beria ◽  
Paolo Cozzi ◽  
Nicoletta Bianchi ◽  
Roberto Gambari ◽  
...  
Keyword(s):  
Growth Inhibition ◽  
Inhibition Activity ◽  
Distamycin A ◽  
Derivatives Of ◽  
Growth Inhibition Activity

scholarly journals Potassium Permanganate-Catalyzed Alpha-Pinene Oxidation: Formation of Coordination Compound with Zinc(II) and Copper(II), and Growth Inhibition Activity on Staphylococcus aureus and Escherichia coli

2018 ◽  
Vol 16 (1) ◽  
pp. 59 ◽  
Author(s):  
Masruri Masruri ◽  
Rekfa Wika Amini ◽  
Mohammad Farid Rahman
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Growth Inhibition ◽  
Potassium Permanganate ◽  
Bacterial Growth ◽  
Complex Compound ◽  
Oxidation Product ◽  
Inhibition Activity ◽  
Alpha Pinene ◽  
Growth Inhibition Activity

Catalytic oxidation of alpha-pinene was investigated using potassium permanganate as an oxidant. The reaction consumed catalyst following stoichiometric amount instead of the catalytic one. The keto-carboxylate compound 2 was afforded as the oxidation product. Further study of its complex compound with copper(II) and zinc(II) was also reported including their activity for inhibiting the growth of Staphylococcus aureus and Escherichia coli. In overall, the complex compound shows important result by inhibiting the bacterial growth.

Sign in / Sign up

Export Citation Format

Share Document