Use of factorial experimental design in static and dynamic light scattering characterization of water-soluble polymers

1995 ◽  
Vol 57 (9) ◽  
pp. 1105-1117
Author(s):  
R. D. Hester ◽  
L. M. Flesher
Keyword(s):  
Light Scattering ◽  
Experimental Design ◽  
Dynamic Light Scattering ◽  
Water Soluble ◽  
Factorial Experimental Design ◽  
Water Soluble Polymers ◽  
Soluble Polymers

Molecular Characterization of Water Soluble Polymers by Field-Flow Fractionation Multiangle Light Scattering FFF-MALS

2013 ◽  
Vol 70 (2) ◽  
pp. 72-81
Author(s):  
Tsuyoshi HIRAMATSU ◽  
Satoshi OHNO ◽  
Yuta SAITO ◽  
Daichi TOGASHI ◽  
Satoshi OHNO ◽  
...  
Keyword(s):  
Light Scattering ◽  
Molecular Characterization ◽  
Water Soluble ◽  
Field Flow Fractionation ◽  
Water Soluble Polymers ◽  
Soluble Polymers ◽  
Flow Fractionation

scholarly journals Self-Assembly of Cholesterol-Containing Water-Soluble Polymers

2012 ◽  
Vol 2012 ◽  
pp. 1-10 ◽  
Author(s):  
Shin-ichi Yusa
Keyword(s):  
Self Assembly ◽  
Liquid Crystalline ◽  
Amphiphilic Polymers ◽  
Water Soluble ◽  
Synthesis And Characterization ◽  
Ordered Structures ◽  
Water Soluble Polymers ◽  
Soluble Polymers ◽  
Nanotechnology Research

Self-assembly of amphiphilic polymers containing cholesteryl groups has proved to be attractive in the field of nanotechnology research. Some cholesterol derivatives are known to form ordered structures which indicate thermotropic and lyotropic liquid-crystalline, monolayers, multilayers, micelles, and liposomes. This paper involves the synthesis and characterization of various kinds of amphiphilic polymers bearing cholesteryl moieties.

scholarly journals Development and characterization of mucoadhesive patches of salbutamol sulfate for unidirectional buccal drug delivery

2011 ◽  
Vol 61 (2) ◽  
pp. 157-170 ◽  
Author(s):  
Ayrivan Puratchikody ◽  
Viswanadhan Prasanth ◽  
Sam Mathew ◽  
Balaraman Kumar
Keyword(s):  
Drug Delivery ◽  
Drug Release ◽  
Water Soluble ◽  
Salbutamol Sulfate ◽  
Water Soluble Polymers ◽  
Soluble Polymers ◽  
Peg 400 ◽  
Buccal Drug Delivery ◽  
Full Factorial

Development and characterization of mucoadhesive patches of salbutamol sulfate for unidirectional buccal drug delivery Buccal patches of salbutamol sulfate were prepared using five different water soluble polymers in various proportions and combinations using PEG-400/PG as plasticizers. A 32 full factorial design was used to design the experiments for each polymer combination. Patches were laminated on one side with a water impermeable backing layer for unidirectional drug release. The thickness of medicated patches ranged between 0.2 and 0.4 mm and showed an increase in mass whenever PEG-400 was used as plasticizer. The surface pH of all patches approached neutral. Eight formulations which had shown high folding endurance (> 300) were selected for evaluation. Patches prepared with PEG-400 showed a high swelling index. The residence time of the tested patches ranged between 105 and 130 min. Formulations A10, A32, B10 and B32 fitted the Higuchi model best, whereas formulations A19 and B19 showed super case II transport drug release. Stability studies indicated that there was no change in the chemical and physical characteristics during the test period of 6 months.

Water-soluble copolymers of 2-methacryloyloxyethyl phosphate: Synthesis and properties

e-Polymers ◽  
2012 ◽  
Vol 12 (1) ◽  
Author(s):  
Vadim V. Annenkov ◽  
Victor A. Pal'shin ◽  
Elena N. Danilovtseva
Keyword(s):  
Light Scattering ◽  
Aqueous Medium ◽  
Silicic Acid ◽  
Isoelectric Point ◽  
Water Soluble ◽  
Scattering Data ◽  
Composite Particles ◽  
Water Soluble Polymers ◽  
Soluble Polymers ◽  
Phosphate Groups

AbstractNew water-soluble polymers with phosphate groups based on 2- methacryloyloxyethyl phosphate have been synthesized by copolymerization with 1-vinyl-2-pyrrolidone and 1-vinylimidazole. The obtained copolymers are polyelectrolytes showing high inclination to aggregation in aqueous medium according to light scattering data. Copolymer of 1-vinylimidazole shows ampholyte properties with isoelectric point at pH 6.8 (6.4 in 0.1M NaCl). Condensation of silicic acid in the presence of this copolymer results in composite particles containing aggregated or non-aggregated copolymer coils with embedded silica.

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