Synthesis of unsaturated polyphosphoester as a potential injectable tissue engineering scaffold materials

2006 ◽  
Vol 102 (4) ◽  
pp. 3095-3101 ◽  
Author(s):  
Jin-Jun Qiu ◽  
Cheng-Mei Liu ◽  
Fen Hu ◽  
Xiao-Dong Guo ◽  
Qi-Xing Zheng
Keyword(s):  
Tissue Engineering ◽  
Tissue Engineering Scaffold ◽  
Scaffold Materials

scholarly journals Tissue Engineering Scaffold Materials to Repair Sports Cartilage Injury

2021 ◽  
Vol 2021 ◽  
pp. 1-9
Author(s):  
Mo Xing
Keyword(s):  
Tissue Engineering ◽  
Stem Cells ◽  
Cell Suspension ◽  
Cell Density ◽  
Porous Scaffold ◽  
Cartilage Damage ◽  
Tissue Engineering Scaffold ◽  
Cartilage Injury ◽  
Culture Bottle ◽  
Scaffold Materials

With the continued development of sports in China, sports sometimes cause cartilage damage. The purpose of this research is to study the tissue engineering scaffold material for sports cartilage damage repair. In this study, mesenchymal rat bone marrow stem cells (to put it simply, stem cells are a type of cell with unlimited or immortal self-renewal capacity, capable of producing at least one type of highly differentiated progeny cells) were obtained by the total bone wash method. The cells were inoculated into the cell culture bottle. When the primary cultured cells proliferated to about 80% of the culture bottle area, the cells were digested with trypsin to open the cell link, then the medium containing 10% serum was added to terminate the cell digestion, and then the passage expansion was carried out according to the cell density. PLGA/NHA and PLGA were heated to 65°C under ultrasonic vibration until uniform PLGA/NHA and PLGA solutions were obtained. Then, the samples were added to the tube mold and then heated and cooled to obtain the composite porous scaffold of mesenchymal stem cells. 10 μl MSCs cell suspension was extracted with a microinjector, and the needle was injected from the inside of the scaffold, and the cell suspension was added outside the scaffold to ensure that there were composite cells inside and outside the scaffold. The subcutaneous tissue of the skin was cut along the medial side of the knee joint and the capsule of the switch segment was cut. The scaffold materials were filled into the osteochondral defect to observe the cartilage healing. The mechanical strength of 0.5% PLGA-MSCs composite porous scaffold was increased to 1.1 MPa, and the cell density was high. The repair of cartilage in rats was the best. The results showed that the porous scaffolds designed in this study have good compatibility and are beneficial to repair sports cartilage injury.

A vascular tissue engineering scaffold with core–shell structured nano-fibers formed by coaxial electrospinning and its biocompatibility evaluation

2016 ◽  
Vol 11 (3) ◽  
pp. 035007 ◽  
Author(s):  
Nannan Duan ◽  
Xue Geng ◽  
Lin Ye ◽  
Aiying Zhang ◽  
Zengguo Feng ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Vascular Tissue ◽  
Tissue Engineering Scaffold ◽  
Vascular Tissue Engineering ◽  
Coaxial Electrospinning ◽  
Core Shell

Bisphosphonate-functionalized poly(amido amine) crosslinked 2-hydroxyethyl methacrylate hydrogel as tissue engineering scaffold

2021 ◽  
Vol 159 ◽  
pp. 110732
Author(s):  
Melek Naz Guven ◽  
Burcu Balaban ◽  
Gozde Demirci ◽  
Havva Yagci Acar ◽  
Oguz Okay ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Tissue Engineering Scaffold ◽  
Hydroxyethyl Methacrylate

A Honeycomb Collagen Carrier for Cell Culture as a Tissue Engineering Scaffold

2001 ◽  
Vol 25 (3) ◽  
pp. 213-217 ◽  
Author(s):  
Hiroshi Itoh ◽  
Yu Aso ◽  
Masayasu Furuse ◽  
Yasuharu Noishiki ◽  
Teruo Miyata
Keyword(s):  
Tissue Engineering ◽  
Cell Culture ◽  
Tissue Engineering Scaffold
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