Effect of annealing on morphologies and performances of hydroxypropyl methylcellulose/hydroxypropyl starch blends

2020 ◽  
Vol 137 (47) ◽  
pp. 49535
Author(s):  
Ying Chen ◽  
Lisha Liao ◽  
Hongsheng Liu ◽  
Yanfei Wang ◽  
Liang Zhang ◽  
...  
Keyword(s):  
Hydroxypropyl Methylcellulose ◽  
Starch Blends ◽  
Hydroxypropyl Starch

Developing hydroxypropyl methylcellulose/hydroxypropyl starch blends for use as capsule materials

2013 ◽  
Vol 98 (1) ◽  
pp. 73-79 ◽  
Author(s):  
Liang Zhang ◽  
Yanfei Wang ◽  
Hongsheng Liu ◽  
Long Yu ◽  
Xingxun Liu ◽  
...  
Keyword(s):  
Hydroxypropyl Methylcellulose ◽  
Starch Blends ◽  
Hydroxypropyl Starch

Rheological and gel properties of hydroxypropyl methylcellulose/hydroxypropyl starch blends

2014 ◽  
Vol 293 (1) ◽  
pp. 229-237 ◽  
Author(s):  
Liang Zhang ◽  
Yanfei Wang ◽  
Long Yu ◽  
Hongsheng Liu ◽  
George Simon ◽  
...  
Keyword(s):  
Hydroxypropyl Methylcellulose ◽  
Gel Properties ◽  
Starch Blends ◽  
Hydroxypropyl Starch

Effect of processing conditions on microstructures and properties of hydroxypropyl methylcellulose/hydroxypropyl starch blends

2017 ◽  
Vol 70 ◽  
pp. 251-259 ◽  
Author(s):  
Liang Zhang ◽  
Long Yu ◽  
Hongsheng Liu ◽  
Yanfei Wang ◽  
George P. Simon ◽  
...  
Keyword(s):  
Hydroxypropyl Methylcellulose ◽  
Processing Conditions ◽  
Starch Blends ◽  
Hydroxypropyl Starch

Relationship between morphologies and mechanical properties of hydroxypropyl methylcellulose/hydroxypropyl starch blends

2016 ◽  
Vol 153 ◽  
pp. 329-335 ◽  
Author(s):  
Yanfei Wang ◽  
Liang Zhang ◽  
Hongsheng Liu ◽  
Long Yu ◽  
George P. Simon ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Hydroxypropyl Methylcellulose ◽  
Starch Blends ◽  
Hydroxypropyl Starch

scholarly journals STRENGTH IMPROVEMENT OF HYDROXYPROPYL METHYLCELLULOSE/ STARCH FILMS USING CELLULOSE NANOCRYSTALS

CERNE ◽  
2017 ◽  
Vol 23 (4) ◽  
pp. 423-434 ◽  
Author(s):  
Ney Robson Taironi do Prado ◽  
Joabel Raabe ◽  
Seyedmohammad Mirmehdi ◽  
Lisiane Nunes Hugen ◽  
Lidiane Costa Lima ◽  
...  
Keyword(s):  
Electron Microscopy ◽  
Mechanical Properties ◽  
Fracture Surface ◽  
Cellulose Nanocrystals ◽  
Hydroxypropyl Methylcellulose ◽  
X Ray Diffraction ◽  
Homogeneous Surface ◽  
Transmission Electron ◽  
Tensile Performance ◽  
Starch Blends

ABSTRACT Interest in cellulose nanocrystals obtained from natural resources has grown mainly because of features that such materials provide when inserted into polymeric matrices. The present study aimed to evaluate the effect of cellulose nanocrystals addition on mechanical properties of biofilms made from hypromellose (or hydroxypropyl methylcellulose - HPMC) and cassava starch blends (CS). The cellulose nanocrystals were produced by acid hydrolysis and characterized by optical microscopy (OM), transmission electron microscopy (TEM), X-ray diffraction (XRD) and thermogravimetry (TG). Films were made with pure CS, pure hypromellose and also with blends of CS and hypromellose by casting. Then cellulose nanocrystals were added to the blends in the concentrations of 1, 3 and 10% (m/m). Evaluations of the films included tensile performance and fracture surface by scanning electron microscopy (SEM). It was observed that the reinforcement with nanocrystals improved the mechanical properties of the films, and their fracture surface showed that cellulose nanocrystals promoted an improvement in the cohesion of the hypromellose and starch molecules in the blend, and created a more homogeneous surface.

scholarly journals High-Payload Buccal Delivery System of Amorphous Curcumin–Chitosan Nanoparticle Complex in Hydroxypropyl Methylcellulose and Starch Films

2021 ◽  
Vol 22 (17) ◽  
pp. 9399
Author(s):  
Li Ming Lim ◽  
Kunn Hadinoto
Keyword(s):  
Oral Delivery ◽  
Hydroxypropyl Methylcellulose ◽  
Buccal Delivery ◽  
Limited Effectiveness ◽  
First Pass Metabolism ◽  
First Pass ◽  
Starch Films ◽  
Hydroxypropyl Starch ◽  
High Payload ◽  
Pass Metabolism

Oral delivery of curcumin (CUR) has limited effectiveness due to CUR’s poor systemic bioavailability caused by its first-pass metabolism and low solubility. Buccal delivery of CUR nanoparticles can address the poor bioavailability issue by virtue of avoidance of first-pass metabolism and solubility enhancement afforded by CUR nanoparticles. Buccal film delivery of drug nanoparticles, nevertheless, has been limited to low drug payload. Herein, we evaluated the feasibilities of three mucoadhesive polysaccharides, i.e., hydroxypropyl methylcellulose (HPMC), starch, and hydroxypropyl starch as buccal films of amorphous CUR–chitosan nanoplex at high CUR payload. Both HPMC and starch films could accommodate high CUR payload without adverse effects on the films’ characteristics. Starch films exhibited far superior CUR release profiles at high CUR payload as the faster disintegration time of starch films lowered the precipitation propensity of the highly supersaturated CUR concentration generated by the nanoplex. Compared to unmodified starch, hydroxypropyl starch films exhibited superior CUR release, with sustained release of nearly 100% of the CUR payload in 4 h. Hydroxypropyl starch films also exhibited good payload uniformity, minimal weight/thickness variations, high folding endurance, and good long-term storage stability. The present results established hydroxypropyl starch as the suitable mucoadhesive polysaccharide for high-payload buccal film applications.

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