Silk fibroin electrospun nanofiber blends with antibiotics and polyvinyl alcohol for burn wound healing

2021 ◽  
pp. 51930
Author(s):  
Aparna Yerra ◽  
Mary Mamatha Dadala
Keyword(s):  
Wound Healing ◽  
Polyvinyl Alcohol ◽  
Silk Fibroin ◽  
Electrospun Nanofiber ◽  
Burn Wound ◽  
Burn Wound Healing

Anti-inflammatory effect of epidermal growth factor conjugated silk fibroin immobilized polyurethane ameliorates diabetic burn wound healing

2020 ◽  
Vol 143 ◽  
pp. 1009-1032 ◽  
Author(s):  
Sohini Sen ◽  
Piyali Basak ◽  
Bishnu Prasad Sinha ◽  
Praveen Maurye ◽  
Krishna Kumar Jaiswal ◽  
...  
Keyword(s):  
Wound Healing ◽  
Growth Factor ◽  
Epidermal Growth Factor ◽  
Silk Fibroin ◽  
Burn Wound ◽  
Burn Wound Healing ◽  
Epidermal Growth ◽  
Anti Inflammatory ◽  
Inflammatory Effect

Antibiotic‐based silk fibroin films for burn wound healing

2020 ◽  
Author(s):  
Aparna Yerra ◽  
Mamatha D. M.
Keyword(s):  
Wound Healing ◽  
Silk Fibroin ◽  
Burn Wound ◽  
Burn Wound Healing

Silk fibroin hydrogel promote burn wound healing through regulating TLN1 expression and affecting cell adhesion and migration

2020 ◽  
Vol 31 (5) ◽  
Author(s):  
Ying Guan ◽  
Feng Sun ◽  
Xiaojuan Zhang ◽  
Zhibin Peng ◽  
Bo jiang ◽  
...  
Keyword(s):  
Wound Healing ◽  
Cell Adhesion ◽  
Silk Fibroin ◽  
Burn Wound ◽  
Burn Wound Healing ◽  
Cell Adhesion And Migration ◽  
And Migration

The Safety and Efficacy of Mupirocin Topical Spray for Burn Wound Healing in A Rat Model

2019 ◽  
Vol 10 (01) ◽  
Author(s):  
Sritharadol Rutthapol ◽  
Chunhachaichana Charisopon ◽  
Kumlungmak Sukanjana ◽  
Buatong Wilaiporn ◽  
Dechraksa Janwit ◽  
...  
Keyword(s):  
Wound Healing ◽  
Matrix Metalloproteinase ◽  
Rat Model ◽  
Transforming Growth Factor ◽  
Immunohistochemical Study ◽  
Enzyme Linked Immunosorbent Assay ◽  
Burn Wound ◽  
Safety And Efficacy ◽  
Burn Wound Healing ◽  
Tgf Β1

ABSTRACT This study evaluated the effect of mupirocin topical spray on burn wound healing in a rat model. Fifteen male Sprague Dawley rats were used to create full-thickness burns on the rat dorsum using a cylindrical stainless steel rod. The rats were topically treated with normal saline solution (NSS), mupirocin spray, ointment, and solution. The wound size and morphological evaluation were investigated by photographs and clinical criterions for wound healing. The histology was observed by hematoxylin and eosin (HandE) staining assay. The immunohistochemical study was evaluated by detection of transforming growth factor-beta 1 (TGF-β1), and the ratio of matrix metalloproteinase-9 to the tissue inhibitor of matrix metalloproteinase-1 (MMP-9/TIMP-1) was quantified using the enzyme-linked immunosorbent assay (ELISA) assay. A complete healing was observed at 28 days in all treatments. Mupirocin formulations accelerated the wound healing faster than NSS in size. However, the clinical criteria indicated a desirable skin appearance in the mupirocin spray and ointment treated groups. The histological evaluations showed no differences between the treatments while the immunohistochemical study revealed that all treatments reduced the level of TGF-β1 over time, particularly on day 28 in the mupirocin spray and ointment treated groups. The MMP-9/TIMP-1 ratio was significantly lower in the mupirocin spray and ointment treated groups than in the NSS and mupirocin solution groups. This study shows the safety and efficacy in the use of mupirocin topical spray. The topical mupirocin spray is an alternative suitable for development as a human topical anti-infective and wound protection spray.

Evaluation of Liver and Kidney Toxicity in Rats Receiving Proteoglycans from Fish Cartilage for the Acceleration of Burn Wound Healing

2016 ◽  
Vol 11 (01) ◽  
pp. 11-16
Author(s):  
Sitthiphon Bunman ◽  
Narongpon Dumavibhat ◽  
Noppadol Larbcharoensub
Keyword(s):  
Wound Healing ◽  
Burn Wound ◽  
Kidney Toxicity ◽  
Burn Wound Healing ◽  
Liver And Kidney

scholarly journals Validity of thermography for measuring burn wound healing potential

2019 ◽  
Vol 28 (3) ◽  
pp. 347-354 ◽  
Author(s):  
Michelle E. Carrière ◽  
Louise E. M. Haas ◽  
Anouk Pijpe ◽  
Annebeth Meij‐de Vries ◽  
Kim L. M. Gardien ◽  
...  
Keyword(s):  
Wound Healing ◽  
Burn Wound ◽  
Burn Wound Healing

556 The Use of a Concentrated Surfactant Based Gel to Promote Burn Wound Healing

2021 ◽  
Vol 42 (Supplement_1) ◽  
pp. S126-S127
Author(s):  
Rebecca Coffey ◽  
Rachel Penny
Keyword(s):  
Wound Healing ◽  
New Product ◽  
Ease Of Use ◽  
Burn Injuries ◽  
Full Thickness ◽  
Burn Wound ◽  
Burn Wounds ◽  
Burn Care ◽  
Product Trial ◽  
Burn Wound Healing

Abstract Introduction Strategies to remove necrotic tissue from burn wounds include excisional and non-excisional debridement. Alternative treatments could promote burn wound healing while minimizing patient discomfort and the need for surgery. We evaluated the usage of a concentrated surfactant gel (CSG) to promote burn wound healing in those with indeterminate depth and full thickness burn injuries. Methods An IRB approved retrospective study was conducted during a 10-patient new product trial period with enrollment between September and October 2019. Patients included in this study had indeterminate or full thickness burn wounds and were treated with a concentrated surfactant-based gel. Patients with non-burn diagnoses were excluded. Data collected included demographic information, injury descriptors, and additional burn wound characteristics. Results A total of 10 patients were included in this study as part of a new product trial. The subjects were 80% male with an average TBSA of 7.5%. 40% had indeterminate and 60% had full thickness burn wounds. Prior to initiation of the CSG, the burn wounds had been open for an average of 41 days. There were no infections or complications with usage of the CSG. 90% of patients reported less pain than the standard of care topical agents for burns. Average duration of treatment with the CSG until healing was 28 days. After usage of the CSG, no patients required surgery. Conclusions Our findings support the usage of a concentrated surfactant-based gel in patients with burn wounds. Patients reported decreased pain during dressing changes and ease of use compared to the standard topical agent in burn care. It also prevented surgical debridement in those with indeterminate and full thickness burn injuries.

Burn wound healing: James Ellsworth Laing memorial essay for 1991

Burns ◽  
1992 ◽  
Vol 18 (6) ◽  
pp. 466-478 ◽  
Author(s):  
P. Dziewulski
Keyword(s):  
Wound Healing ◽  
Burn Wound ◽  
Burn Wound Healing

Fat Grafting and Adipose-Derived Regenerative Cells in Burn Wound Healing and Scarring

2016 ◽  
Vol 137 (1) ◽  
pp. 302-312 ◽  
Author(s):  
Alexandra Condé-Green ◽  
Andrew A. Marano ◽  
Edward S. Lee ◽  
Tom Reisler ◽  
Leigh Ann Price ◽  
...  
Keyword(s):  
Wound Healing ◽  
Fat Grafting ◽  
Burn Wound ◽  
Burn Wound Healing ◽  
Regenerative Cells
Sign in / Sign up

Export Citation Format

Share Document