The utility of magnetic resonance imaging for assessing structural damage in randomized controlled trials in rheumatoid arthritis: Report from the imaging group of the American College of Rheumatology RA clinical trials task force

2013 ◽  
pp. n/a-n/a ◽  
Author(s):  
Veena K. Ranganath ◽  
Vibeke Strand ◽  
Charles G. Peterfy ◽  
Mikkel Østergaard ◽  
Atul Deodhar ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Magnetic Resonance Imaging ◽  
Clinical Trials ◽  
Magnetic Resonance ◽  
Structural Damage ◽  
Task Force ◽  
Controlled Trials ◽  
Resonance Imaging ◽  
Randomized Controlled ◽  
American College Of Rheumatology

Selecting Magnetic Resonance Imaging (MRI) Outcome Measures for Juvenile Idiopathic Arthritis (JIA) Clinical Trials: First Report of the MRI in JIA Special Interest Group

2013 ◽  
Vol 41 (2) ◽  
pp. 354-358 ◽  
Author(s):  
Robert Hemke ◽  
Andrea S. Doria ◽  
Nikolay Tzaribachev ◽  
Mario Maas ◽  
Désirée M.F.M van der Heijde ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Magnetic Resonance Imaging ◽  
Clinical Trials ◽  
Juvenile Idiopathic Arthritis ◽  
Magnetic Resonance ◽  
Childhood And Adolescence ◽  
Resonance Imaging ◽  
Scoring Method ◽  
Magnetic Resonance Imaging Mri ◽  
Clinical Research Trials

Recent advances in magnetic resonance imaging (MRI) techniques have substantially improved the evaluation of joint pathologies in juvenile idiopathic arthritis (JIA). Because of the current availability of highly effective antirheumatic therapies and the unique and useful features of MRI, there is a growing need for an accurate and reproducible MRI assessment scoring system for JIA, such as the rheumatoid arthritis MRI Scoring (RAMRIS) for patients with rheumatoid arthritis (RA). To effectively evaluate the efficacy of treatment in clinical research trials, we need to develop and validate scoring methods to accurately measure joint outcomes, standardize imaging protocols for data acquisition and interpretation, and create imaging atlases to differentiate physiologic and pathologic joint findings in childhood and adolescence. Such a standardized, validated, JIA-MRI scoring method could be used as an outcome measure in clinical trials.

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