scholarly journals Rosuvastatin-Induced Carotid Plaque Regression in Patients With Inflammatory Joint Diseases: The Rosuvastatin in Rheumatoid Arthritis, Ankylosing Spondylitis and Other Inflammatory Joint Diseases Study

2015 ◽  
Vol 67 (7) ◽  
pp. 1718-1728 ◽  
Author(s):  
S. Rollefstad ◽  
E. Ikdahl ◽  
J. Hisdal ◽  
I. C. Olsen ◽  
I. Holme ◽  
...  
2014 ◽  
Vol 73 (Suppl 2) ◽  
pp. 399.2-399 ◽  
Author(s):  
S. Rollefstad ◽  
E. Ikdahl ◽  
J. Hisdal ◽  
I.C. Olsen ◽  
K.T. Smerud ◽  
...  

2014 ◽  
Vol 235 (2) ◽  
pp. e93
Author(s):  
S. Rollefstad ◽  
E. Ikdahl ◽  
J. Hisdal ◽  
I. Holme ◽  
I.C. Olsen ◽  
...  

Biomedicines ◽  
2021 ◽  
Vol 9 (8) ◽  
pp. 902
Author(s):  
Susanne N. Wijesinghe ◽  
Mark A. Lindsay ◽  
Simon W. Jones

Osteoarthritis (OA) and rheumatoid arthritis (RA) are two of the most common chronic inflammatory joint diseases, for which there remains a great clinical need to develop safer and more efficacious pharmacological treatments. The pathology of both OA and RA involves multiple tissues within the joint, including the synovial joint lining and the bone, as well as the articular cartilage in OA. In this review, we discuss the potential for the development of oligonucleotide therapies for these disorders by examining the evidence that oligonucleotides can modulate the key cellular pathways that drive the pathology of the inflammatory diseased joint pathology, as well as evidence in preclinical in vivo models that oligonucleotides can modify disease progression.


Rheumatology ◽  
2010 ◽  
Vol 49 (4) ◽  
pp. 671-682 ◽  
Author(s):  
A. Baillet ◽  
C. Trocme ◽  
S. Berthier ◽  
M. Arlotto ◽  
L. Grange ◽  
...  

2021 ◽  
Vol 2 (1) ◽  
pp. 25-32
Author(s):  
Danilo Jeremić ◽  
Boris Gluščević ◽  
Stanislav Rajković ◽  
Želimir Jovanović ◽  
Branislav Krivokapić

Osteoarthritis, osteoarthrosis, and osteoarthropathy are diseases that doctors encounter daily in their practice. The use of all three terms is customary, often without a clear justification as to why a particular term is used for a particular case. In the past several decades, doctors mainly differentiated among these diseases based on clinical presentation and radiography. In the past several years, however, significant progress has been made in the field of biochemical, immunological, and cytohistological research, which has provided explanations for the pathogenesis of these conditions, enabled defining differences amongst them and facilitated the use of appropriate terms for each one of these diseases. The term arthritis (osteoarthritis) should be used exclusively for primarily inflammatory joint diseases-rheumatoid arthritis, juvenile arthritis, reactive arthritis (Reiter's syndrome). If the etiology is infectious, this must also be emphasized-septic (purulent) arthritis, tuberculous arthritis. Arthrosis (osteoarthrosis) relates to changes in the joints occurring due to pathological processes within the joint itself, but which, in their basis, are not inflammatory. Arthropathy is a term for joint disease stemming from another diseased organ or system of organs.


2003 ◽  
Vol 38 (1) ◽  
pp. 53-67 ◽  
Author(s):  
Raimund W. Kinne ◽  
Elke Kunisch ◽  
Volkmar Beensen ◽  
Thomas Zimmermann ◽  
Frank Emmrich ◽  
...  

2019 ◽  
pp. 49-54

Chikungunya virus (CHIKV) is an arthritogenic arbovirus infection transmitted through the mosquitoes Aedes aegypti and Aedes albopictus. The clinical picture is diverse - from mildly flowing, almost asymptomatic forms to characteristic episodes of fever, polymyalgia, polyarthralgia, and arthritis. Globalization of the world is increasing the chances of infection spreading outside known endemic areas. This necessitates a broad differential diagnosis, especially in cases that mimic inflammatory joint diseases such as rheumatoid arthritis. The presented clinical case is of a patient who has returned from a trip to the Maldives and is the first in the Republic of Bulgaria as far as we know, and is established after a detailed literature reference has been made. Rheumatologists, even in non-CHIKV-endemic regions, should consider CHIKV in their evaluation of symmetric polyarthritis lasting above six weeks, especially in case of anamnesis for a trip to the endemic regions to CHIKV that are likely to expand in the near future. However, demonstrating positive antibodies to the Chikungunya virus is the rheumatologist‘s primary help in distinguishing the two diseases.


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