scholarly journals Editorial: Wnt Signaling Related to Subchondral Bone Density and Cartilage Degradation in Osteoarthritis

2018 ◽  
Vol 70 (2) ◽  
pp. 157-161 ◽  
Author(s):  
David B. Burr ◽  
Achint Utreja
2007 ◽  
Vol 68 (8) ◽  
pp. 841-849 ◽  
Author(s):  
Benjamin D. Young ◽  
Valerie F. Samii ◽  
John S. Mattoon ◽  
Steven E. Weisbrode ◽  
Alicia L. Bertone

2018 ◽  
Vol 47 (4) ◽  
pp. 566-571 ◽  
Author(s):  
Elizabeth S. Leach ◽  
Ursula Krotscheck ◽  
Kelsey J. Goode ◽  
Galina M. Hayes ◽  
Peter Böttcher

2019 ◽  
Vol 32 (03) ◽  
pp. 207-214
Author(s):  
Walter Dingemanse ◽  
Ingrid Gielen ◽  
Henri van Bree ◽  
Magdalena Müller-Gerbl ◽  
Nikola Krstić ◽  
...  

Objective Subchondral bone density distribution can be used to study joint biomechanics non-invasively. Differences in joint loading between related species can aid in the understanding of joint loading and the development of certain types of orthopaedic pathology. This study was conducted to evaluate density distribution in the subchondral bone of the talus of different Canidae species, as a parameter reflecting the long-term joint loading in the tarsocrural joint. Materials and Methods The tarsal joints of cadaveric dogs of different breeds were included, that is, German Shepherd (n = 5), Bouvier des Flandres (n = 3) and Labrador Retriever (n = 6).Additionally, golden jackals (n = 5) (Canis aureus) and wolves (n = 5) (Canis lupus) were included. Consecutive computed tomography slices were made and the subchondral bone density distribution was evaluated using computer tomographic osteoabsorptiometry. Different breeds and species were visually compared. Results Differences were found in the subchondral bone density distribution of the talus between breeds and between species (Canis familiaris, Canis lupus and Canis aureus). Discussion and Conclusion Based on the density distribution, there are differences in loading conditions of the tarsocrural joint in different species of Canidae. The joint loading distribution is very similar between dogs of the same breed and within the same species. Although between-breed differences can be explained by conformational differences, the between-species differences remain subject to further research.


2020 ◽  
Vol 8 (11) ◽  
pp. 232596712096210
Author(s):  
Daisuke Momma ◽  
Wataru Iwamoto ◽  
Kaori Endo ◽  
Kazuki Sato ◽  
Norimasa Iwasaki

Background: The distribution pattern of subchondral bone density is an indicator of stress distribution over a joint surface under long-term physiologic loading. The biomechanical characteristics of the articular surfaces of the shoulder joint in gymnasts can be determined by measuring this distribution pattern. Purpose: To evaluate the distribution of subchondral bone density across the shoulder joint in male collegiate gymnasts and to determine the effects of gymnastic activities on its articular surfaces under long-term loading conditions using computed tomography osteoabsorptiometry (CTOAM). Study Design: Descriptive laboratory study. Methods: CT image data were obtained from both shoulders of 12 asymptomatic male collegiate gymnasts (gymnast group; mean age, 19.4 years; range, 18-22 years) and 10 male collegiate volunteers (control group; mean age, 20.2 years; range, 18-22 years). The distribution pattern of subchondral bone density across the articular surfaces of each shoulder joint was assessed by CTOAM. Quantitative analysis was performed of the locations and percentages of high-density areas on the articular surface. Results: Stress distribution patterns over the articular surfaces differed between the gymnasts and the controls. In the gymnasts, high-density areas were detected on the posterosuperior articular surface of the humeral head and the anterosuperior and/or posterosuperior articular surface of the glenoid. Mean bone density was greater in the gymnasts than in the controls ( P < .0001). Conclusion: Stress distribution over the articular surfaces of the shoulder joint was affected by gymnastic activities. Stress was concentrated over the superior part of the glenohumeral joint in male collegiate gymnasts. Clinical Relevance: The present findings suggest that gymnastic activities increase stress to the articular surfaces of the superior glenohumeral joint. This supports the notion that mechanical conditions play a crucial role in the origin of disorders particular to gymnastic activities.


2019 ◽  
Vol 49 (4) ◽  
pp. 571-576
Author(s):  
Chien-Chou Pan ◽  
Peter Simon ◽  
Alejandro A. Espinoza Orías ◽  
Ryota Takatori ◽  
Howard S. An ◽  
...  

2020 ◽  
Vol 8 (11) ◽  
pp. 232596712096308
Author(s):  
Junki Shiota ◽  
Daisuke Momma ◽  
Takayoshi Yamaguchi ◽  
Norimasa Iwasaki

Background: The distribution pattern of subchondral bone density is considered to accurately reflect the stress distribution over a joint under long-term physiologic loading. The biomechanical characteristics of the surface of the ankle joint in soccer players can be determined by measuring this distribution pattern under long-term loading. Purpose: To evaluate the distribution of subchondral bone density across the ankle joint in soccer players and to determine the effects of soccer activities, including kicking motion, on the ankle joint surface under long-term loading conditions by computed tomography (CT) osteoabsorptiometry (CTOAM). Study Design: Cross-sectional study; Level of evidence, 3. Methods: CT imaging data were obtained from both ankles of 10 soccer players (soccer group) and 10 nonathletic volunteers (control group). The distribution patterns of subchondral bone density across the articular surface of the ankle joints were assessed by CTOAM. Quantitative analysis was performed of the locations and percentages of high-density areas on the articular surface. Results: Stress distribution patterns over the ankle joint differed between the soccer players and controls. In the soccer players, the high-density areas were found in the anterior part of the distal tibia and proximal talus as well as the distal fibula. The percentages of high-density areas were greater in the soccer players compared with controls ( P < .0001). Conclusion: Stress distribution over the articular surface of the ankle joint was affected by soccer activities. A high stress concentration was seen in soccer players in the anterior part of the tibia and talus and in the fibula; such excessive stress may lead to anterior impingement.


2016 ◽  
Vol 12 (1) ◽  
Author(s):  
W. Dingemanse ◽  
M. Müller-Gerbl ◽  
I. Jonkers ◽  
J. Vander Sloten ◽  
H. van Bree ◽  
...  

2008 ◽  
Vol 30 (2) ◽  
pp. 113-118 ◽  
Author(s):  
T. C. Koslowsky ◽  
K. Mader ◽  
A. Brandenburg ◽  
M. Hellmich ◽  
J. Koebke

2004 ◽  
Vol 423 ◽  
pp. 259-263 ◽  
Author(s):  
Christoph Udo Schulz ◽  
Hermann Anetzberger ◽  
Manfred Pfahler ◽  
Hans J??rgen Refior ◽  
Magdalena M??ller-Gerbl

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