scholarly journals Efficacy, Safety, and Pharmacodynamic Effects of the Bruton’s Tyrosine Kinase Inhibitor, Fenebrutinib (GDC‐0853), in Systemic Lupus Erythematosus

2021 ◽  
Author(s):  
David Isenberg ◽  
Richard Furie ◽  
Nicholas S. Jones ◽  
Pascal Guibord ◽  
Joshua Galanter ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Tyrosine Kinase ◽  
Tyrosine Kinase Inhibitor ◽  
Lupus Erythematosus ◽  
Kinase Inhibitor ◽  
Bruton’S Tyrosine Kinase ◽  
Systemic Lupus ◽  
Bruton's Tyrosine Kinase ◽  
Pharmacodynamic Effects

Bruton's tyrosine kinase in systemic lupus erythematosus

2020 ◽  
Vol 87 (6) ◽  
pp. 670-672
Author(s):  
Hsien-Tzung Liao ◽  
Hsiang-Yuen Tung ◽  
Chang-Youh Tsai ◽  
Bor-Luen Chiang ◽  
Chia-Li Yu
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Tyrosine Kinase ◽  
Lupus Erythematosus ◽  
Bruton’S Tyrosine Kinase ◽  
Systemic Lupus ◽  
Bruton's Tyrosine Kinase

Separation of Bruton’s tyrosine kinase inhibitor atropisomers by supercritical fluid chromatography

2019 ◽  
Vol 1586 ◽  
pp. 106-115 ◽  
Author(s):  
Shiuhang Henry Yip ◽  
Dauh-Rurng Wu ◽  
Peng Li ◽  
Dawn Sun ◽  
Scott H. Watterson ◽  
...  
Keyword(s):  
Tyrosine Kinase ◽  
Tyrosine Kinase Inhibitor ◽  
Supercritical Fluid ◽  
Supercritical Fluid Chromatography ◽  
Kinase Inhibitor ◽  
Bruton’S Tyrosine Kinase ◽  
Bruton's Tyrosine Kinase

scholarly journals Development of an Efficient Manufacturing Process for Reversible Bruton’s Tyrosine Kinase Inhibitor GDC-0853

2018 ◽  
Vol 22 (8) ◽  
pp. 978-990 ◽  
Author(s):  
Haiming Zhang ◽  
Theresa Cravillion ◽  
Ngiap-Kie Lim ◽  
Qingping Tian ◽  
Danial Beaudry ◽  
...  
Keyword(s):  
Tyrosine Kinase ◽  
Tyrosine Kinase Inhibitor ◽  
Manufacturing Process ◽  
Kinase Inhibitor ◽  
Bruton’S Tyrosine Kinase ◽  
Bruton's Tyrosine Kinase ◽  
Efficient Manufacturing

scholarly journals Long-term follow-up of patients with CLL treated with the selective Bruton’s tyrosine kinase inhibitor ONO/GS-4059

Blood ◽  
2017 ◽  
Vol 129 (20) ◽  
pp. 2808-2810 ◽  
Author(s):  
Harriet S. Walter ◽  
Sandrine Jayne ◽  
Simon A. Rule ◽  
Guillaume Cartron ◽  
Franck Morschhauser ◽  
...  
Keyword(s):  
Tyrosine Kinase ◽  
Tyrosine Kinase Inhibitor ◽  
Kinase Inhibitor ◽  
Bruton’S Tyrosine Kinase ◽  
Bruton's Tyrosine Kinase ◽  
Long Term Follow Up

Strategies to overcome resistance mutations of Bruton's tyrosine kinase inhibitor ibrutinib

2018 ◽  
Vol 10 (3) ◽  
pp. 343-356 ◽  
Author(s):  
Linyi Liu ◽  
Bingyu Shi ◽  
Xiangqian Wang ◽  
Hua Xiang
Keyword(s):  
Tyrosine Kinase ◽  
Tyrosine Kinase Inhibitor ◽  
Kinase Inhibitor ◽  
Bruton’S Tyrosine Kinase ◽  
Resistance Mutations ◽  
Bruton's Tyrosine Kinase

Bruton’s tyrosine kinase inhibitor suppresses imiquimod-induced psoriasis-like inflammation in mice through regulation of IL-23/IL-17A in innate immune cells

2020 ◽  
Vol 80 ◽  
pp. 106215 ◽  
Author(s):  
Ahmed Nadeem ◽  
Sheikh F. Ahmad ◽  
Naif O. Al-Harbi ◽  
Ahmad M. El-Sherbeeny ◽  
Abullah F Alasmari ◽  
...  
Keyword(s):  
Tyrosine Kinase ◽  
Tyrosine Kinase Inhibitor ◽  
Immune Cells ◽  
Kinase Inhibitor ◽  
Innate Immune ◽  
Innate Immune Cells ◽  
Bruton’S Tyrosine Kinase ◽  
Bruton's Tyrosine Kinase

Safety, Pharmacokinetics, and Pharmacodynamics in Healthy Volunteers Treated With GDC-0853, a Selective Reversible Bruton's Tyrosine Kinase Inhibitor

2018 ◽  
Vol 103 (6) ◽  
pp. 1020-1028 ◽  
Author(s):  
Ann E. Herman ◽  
Leslie W. Chinn ◽  
Shweta G. Kotwal ◽  
Elaine R. Murray ◽  
Rui Zhao ◽  
...  
Keyword(s):  
Tyrosine Kinase ◽  
Healthy Volunteers ◽  
Tyrosine Kinase Inhibitor ◽  
Kinase Inhibitor ◽  
Bruton’S Tyrosine Kinase ◽  
Pharmacokinetics And Pharmacodynamics ◽  
Bruton's Tyrosine Kinase
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