Human umbilical blood mononuclear cell-derived mesenchymal stem cells serve as interleukin-21 gene delivery vehicles for epithelial ovarian cancer therapy in nude mice

2011 ◽  
Vol 58 (6) ◽  
pp. 397-404 ◽  
Author(s):  
Weihua Hu ◽  
Jing Wang ◽  
Xiangfeng He ◽  
Hongyi Zhang ◽  
Fangliu Yu ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Cancer Therapy ◽  
Gene Delivery ◽  
Epithelial Ovarian Cancer ◽  
Umbilical Blood ◽  
Delivery Vehicles ◽  
Interleukin 21 ◽  
Gene Delivery Vehicles

scholarly journals Functionalized MoS2 Nanosheets as Multi-Gene Delivery Vehicles for In Vivo Pancreatic Cancer Therapy

2018 ◽  
Vol 2 (4) ◽  
pp. 371-386 ◽  
Author(s):  
Feng Yin ◽  
Tommy Anderson ◽  
Nishtha Panwar ◽  
Kang Zhang ◽  
Swee Chuan Tjin ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Cancer Therapy ◽  
Gene Delivery ◽  
Mos2 Nanosheets ◽  
Delivery Vehicles ◽  
Pancreatic Cancer Therapy ◽  
Gene Delivery Vehicles

Biomaterials and stem cells as drug/gene-delivery vehicles for Parkinson's treatment: an update

2021 ◽  
Vol 16 (12) ◽  
pp. 1057-1072
Author(s):  
Milad Roshani ◽  
Nasim Kiaie ◽  
Rouhollah Mehdinavaz Aghdam
Keyword(s):  
Parkinson’S Disease ◽  
Stem Cells ◽  
Parkinson's Disease ◽  
Gene Delivery ◽  
Brain Targeting ◽  
Therapeutic Approaches ◽  
Disease Treatment ◽  
Polymeric Particles ◽  
Delivery Vehicles ◽  
Gene Delivery Vehicles

By introducing biomaterials and stem cells into Parkinson’s disease (PD), therapeutic approaches have led to promising results due to facilitating brain targeting and blood–brain barrier permeation of the drugs and genes. Here, after reviewing the most recent drug- and gene-delivery vehicles including liposomes, exosomes, natural/synthetic polymeric particles/fibers, metallic/ceramic nanoparticles and microbubbles, used for Parkinson’s disease treatment, the effect of stem cells as a reservoir of neurotrophic factors and exosomes is provided.

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