scholarly journals The importance of appropriate controls, animal feed, and animal models in interpreting results from low-dose studies of bisphenol A

2005 ◽  
Vol 73 (3) ◽  
pp. 140-145 ◽  
Author(s):  
Frederick S. vom Saal ◽  
Catherine A. Richter ◽  
Rachel R. Ruhlen ◽  
Susan C. Nagel ◽  
Barry G. Timms ◽  
...  
2019 ◽  
Author(s):  
Sabina Šturm ◽  
Andrej Škibin ◽  
Iztok Grabnar ◽  
Milan Pogačnik ◽  
Vesna Cerkvenik Flajs

Abstract • Background: Dietary intake is the predominant route for human exposure to bisphenol A and one of the food items important for humans is milk, and BPA-polluted animal feed and environments may thus affect human exposure. The aim of our study was to evaluate the BPA exposure and disposition in sheep milk after repeated dietary and subcutaneous administration of a relatively low dose (100 µg/kg of body weight per day) of BPA to a sheep. • Results: With our toxicokinetic model, we showed that most likely only free BPA passes into the mammary gland and is subsequently conjugated there. The percentage of the dose eliminated with milk was less than 0.1%, regardless of the route of BPA administration. • Conclusions: It is proven that the BPA is eliminated through the milk of lactating sheep. However, the amounts excreted in the milk that were detected in this study are minimal.


2012 ◽  
Vol 211 ◽  
pp. S159
Author(s):  
Sofiane Boudalia ◽  
Raymond Berges ◽  
Franck Menetrier ◽  
Cécile Helies ◽  
Marie-Chantal Canivenc-Lavier

2002 ◽  
Vol 16 (2) ◽  
pp. 117-122 ◽  
Author(s):  
Shizuka Honma ◽  
Atsuko Suzuki ◽  
David L. Buchanan ◽  
Yoshinao Katsu ◽  
Hajime Watanabe ◽  
...  

2011 ◽  
Vol 71 ◽  
pp. e280-e281
Author(s):  
Yuki Tsuneyoshi ◽  
Akira Masuda ◽  
Kimiya Narikiyo ◽  
Nami Someya ◽  
Shuji Aou

Conjecturas ◽  
2022 ◽  
Vol 22 (1) ◽  
pp. 37-49
Author(s):  
Cristian Ferreira ◽  
Miguelangelo Ziegler Arboitte ◽  
Franciele de Oliveira Oliveira ◽  
Juliana Muliterno Thurow ◽  
Liliane Cerdotes ◽  
...  

The objective was to determine the exact moisture percentage for the formation of pellets from the banana peel, residues of banana candies, and the bromatological analysis of the final product. For the of the peel of banana, 10 different dehydration times were performed: zero; two; four; six; eight; ten; twelve; fourteen; sixteen and eighteen hours of dehydration, with four replicates each treatment. The exact moisture percentage for pellet formation was 18.84% moisture. The final product presented in its bromatological composition  81,16% of DM, 8,59% of CP, 26,8% of TND , 71,48% of NDF, 54,64% ADF, 0,8% of EE, 13,43% MM, 86,54% of OM, 0,22% of P e 0,068% of K. Evaluations in animal models should be performed in place of corn to determine the replacement levels in the diets and the performance of the animals.


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