scholarly journals Survival of aging CD264 + and CD264 − populations of human bone marrow mesenchymal stem cells is independent of colony‐forming efficiency

2019 ◽  
Vol 117 (1) ◽  
pp. 223-237 ◽  
Author(s):  
Sean D. Madsen ◽  
Sean H. Jones ◽  
H. Alan Tucker ◽  
Margaret K. Giler ◽  
Dyllan C. Muller ◽  
...  
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Mesenchymal Stem Cells ◽  
Human Bone ◽  
Human Bone Marrow ◽  
Colony Forming Efficiency ◽  
Marrow Mesenchymal Stem Cells ◽  
Forming Efficiency

Candidate kinases for adipogenesis and osteoblastogenesis from human bone marrow mesenchymal stem cells

2021 ◽  
Author(s):  
Xia Yi ◽  
Ping Wu ◽  
Jianyun Liu ◽  
Shan He ◽  
Ying Gong ◽  
...  
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Mesenchymal Stem Cells ◽  
Transcription Factors ◽  
Human Bone ◽  
Human Bone Marrow ◽  
Cytoplasmic Proteins ◽  
Marrow Mesenchymal Stem Cells

Adipogenesis and osteoblastogenesis (adipo-osteoblastogenesis) are closely related processes involving with the phosphorylation of numerous cytoplasmic proteins and key transcription factors.

Comparative analysis of human bone marrow mesenchymal stem cells, articular cartilage derived chondroprogenitors and chondrocytes to determine cell superiority for cartilage regeneration

2021 ◽  
Vol 123 (4) ◽  
pp. 151713
Author(s):  
Elizabeth Vinod ◽  
Roshni Parameswaran ◽  
Soosai Manickam Amirtham ◽  
Grace Rebekah ◽  
Upasana Kachroo
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Mesenchymal Stem Cells ◽  
Comparative Analysis ◽  
Articular Cartilage ◽  
Cartilage Regeneration ◽  
Human Bone ◽  
Human Bone Marrow ◽  
Marrow Mesenchymal Stem Cells

The red-light emitting diode irradiation increases proliferation of human bone marrow mesenchymal stem cells preserving their immunophenotype

2021 ◽  
pp. 1-11
Author(s):  
Rafał B. Lewandowski ◽  
Małgorzata Stępińska ◽  
Andrzej Gietka ◽  
Monika Dobrzyńska ◽  
Mariusz P. Łapiński ◽  
...  
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Mesenchymal Stem Cells ◽  
Light Emitting Diode ◽  
Red Light ◽  
Human Bone ◽  
Human Bone Marrow ◽  
Light Emitting ◽  
Marrow Mesenchymal Stem Cells

Inner ear progenitor cells can be generated in vitro from human bone marrow mesenchymal stem cells

2012 ◽  
Vol 7 (6) ◽  
pp. 757-767 ◽  
Author(s):  
Sarah L Boddy ◽  
Wei Chen ◽  
Ricardo Romero-Guevara ◽  
Lucksy Kottam ◽  
Illaria Bellantuono ◽  
...  
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Mesenchymal Stem Cells ◽  
Inner Ear ◽  
Progenitor Cells ◽  
Human Bone ◽  
Human Bone Marrow ◽  
Marrow Mesenchymal Stem Cells

Shrinkage-free preparation of scaffold-free cartilage-like disk-shaped cell sheet using human bone marrow mesenchymal stem cells

2011 ◽  
Vol 111 (4) ◽  
pp. 489-492 ◽  
Author(s):  
Satoshi Maeda ◽  
Takashi Fujitomo ◽  
Takahiro Okabe ◽  
Shigeyuki Wakitani ◽  
Mutsumi Takagi
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Mesenchymal Stem Cells ◽  
Cell Sheet ◽  
Human Bone ◽  
Human Bone Marrow ◽  
Shaped Cell ◽  
Marrow Mesenchymal Stem Cells

scholarly journals Exosomal hsa_circ_0006859 is a potential biomarker for postmenopausal osteoporosis and enhances adipogenic versus osteogenic differentiation in human bone marrow mesenchymal stem cells by sponging miR-431-5p

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Feng Zhi ◽  
Yi Ding ◽  
Rong Wang ◽  
Yujiao Yang ◽  
Kaiming Luo ◽  
...  
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Mesenchymal Stem Cells ◽  
Postmenopausal Osteoporosis ◽  
Target Gene ◽  
Human Bone ◽  
Human Bone Marrow ◽  
Healthy Controls ◽  
Potential Biomarker ◽  
Marrow Mesenchymal Stem Cells

Abstract Background As one of the most common chronic diseases in the world, osteoporosis occurs especially in postmenopausal women. Circular RNAs (circRNAs) are emerging as major drivers in human disease. The aim of the present study was to analyse circRNA expression profiles in osteoporosis and to explore the clinical significance and the regulatory molecular mechanism of hsa_circ_0006859 during osteoporosis. Methods Exosomes were isolated from clinically collected serum samples. A circRNA microarray was performed to screen differentially expressed circRNAs. Quantitative real-time PCR (qRT-PCR) and western blot were performed to analyse target gene mRNA expression and protein expression. Alizarin red staining (ARS) was performed to evaluate the mineralization ability of human bone marrow mesenchymal stem cells (hBMSCs). Oil Red O staining was performed to evaluate the lipid droplet formation ability of hBMSCs. Bioinformatics analysis and the luciferase reporter assay were performed to investigate the interaction between two genes. Results Hsa_circ_0006859 was identified as one of the most upregulated circRNAs in the microarray analysis. Hsa_circ_0006859 in exosomes was upregulated in osteoporosis patients compared to healthy controls. Hsa_circ_0006859 differentiated osteopenia or osteoporosis patients from healthy controls with high sensitivity and specificity. Hsa_circ_0006859 suppressed osteoblastic differentiation and promoted adipogenic differentiation of hBMSCs. Hsa_circ_0006859 directly bound to miR-431-5p, and ROCK1 was identified as a novel target gene of miR-431-5p. Hsa_circ_0006859 is a competing endogenous RNA (ceRNA) of miR-431-5p that promotes ROCK1 expression. Hsa_circ_0006859 suppressed osteogenesis and promoted adipogenesis by sponging miR-431-5p to upregulate ROCK1. Conclusions Exosomal hsa_circ_0006859 is a potential biomarker for postmenopausal osteoporosis and controls the balance between osteogenesis and adipogenesis in hBMSCs by sponging miR-431-5p.

scholarly journals Effects of simulated microgravity on the expression profiles of RNA during osteogenic differentiation of human bone marrow mesenchymal stem cells

2018 ◽  
Vol 52 (2) ◽  
pp. e12539 ◽  
Author(s):  
Liang Li ◽  
Cui Zhang ◽  
Jian‐ling Chen ◽  
Fan‐fan Hong ◽  
Ping Chen ◽  
...  
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Mesenchymal Stem Cells ◽  
Osteogenic Differentiation ◽  
Simulated Microgravity ◽  
Expression Profiles ◽  
Human Bone ◽  
Human Bone Marrow ◽  
Marrow Mesenchymal Stem Cells

scholarly journals N-Glycosylation Profile of Undifferentiated and Adipogenically Differentiated Human Bone Marrow Mesenchymal Stem Cells: Towards a Next Generation of Stem Cell Markers

2013 ◽  
Vol 22 (23) ◽  
pp. 3100-3113 ◽  
Author(s):  
Houda Hamouda ◽  
Mujib Ullah ◽  
Markus Berger ◽  
Michael Sittinger ◽  
Rudolf Tauber ◽  
...  
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Mesenchymal Stem Cells ◽  
Stem Cell ◽  
Human Bone ◽  
Human Bone Marrow ◽  
Stem Cell Markers ◽  
Next Generation ◽  
Cell Markers ◽  
Marrow Mesenchymal Stem Cells

scholarly journals Role of (-)-epigallocatechin-3-gallate in the osteogenic differentiation of human bone marrow mesenchymal stem cells: An enhancer or an inducer?

2015 ◽  
Vol 10 (2) ◽  
pp. 828-834 ◽  
Author(s):  
PAN JIN ◽  
MUYAN LI ◽  
GUOJIE XU ◽  
KUN ZHANG ◽  
LI ZHENG ◽  
...  
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Mesenchymal Stem Cells ◽  
Osteogenic Differentiation ◽  
Human Bone ◽  
Human Bone Marrow ◽  
Marrow Mesenchymal Stem Cells
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