A rapid and sensitive LC-MS/MS method for evaluation of the absolute oral bioavailability of a novel c-Met tyrosine kinase inhibitor QBH-196 in rats

2015 ◽  
Vol 29 (11) ◽  
pp. 1650-1656 ◽  
Author(s):  
Qi. Zhang ◽  
Jin Sun ◽  
Tianshu Lu ◽  
Jinling Zhang ◽  
Chunnuan Wu ◽  
...  
Keyword(s):  
Tyrosine Kinase ◽  
Tyrosine Kinase Inhibitor ◽  
Oral Bioavailability ◽  
Kinase Inhibitor ◽  
Absolute Oral Bioavailability ◽  
The Absolute

Tyrosine kinase inhibitor (TKI) treatment outcome of stage IV-C thyroid differentiated cancer (analyzed by lesion evaluation)

2018 ◽  
Author(s):  
Hiroyuki Iwasaki ◽  
Haruhiko Yamazaki ◽  
Nobuyasu Suganuma ◽  
Yuko Sugawara ◽  
Naoki Gotoh ◽  
...  
Keyword(s):  
Treatment Outcome ◽  
Tyrosine Kinase ◽  
Tyrosine Kinase Inhibitor ◽  
Kinase Inhibitor ◽  
Stage Iv ◽  
Tki Treatment
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