Flow cytometric determination of cell cycle phase-specific changes in cellular phosphatase and glycosidase activities

1987 ◽  
Vol 5 (1) ◽  
pp. 17-26
Author(s):  
R. A. Britten ◽  
J. E. D. Dyson
2013 ◽  
Vol 85 (19) ◽  
pp. 8996-9002 ◽  
Author(s):  
Stanislav O. Konorov ◽  
H. Georg Schulze ◽  
James M. Piret ◽  
Michael W. Blades ◽  
Robin F. B. Turner

2006 ◽  
Vol 24 (18_suppl) ◽  
pp. 20105-20105
Author(s):  
Y. Chen ◽  
X. Yu

20105 Background: To observe the effect and mechanism of gemcitabine-induced radiosensitization on CNE-1 nasopharyngeal carcinoma cell line. Methods: The cell survival curves were obtained with clonogenic assay. The cell cycle phases were measured with flow cytometric analysis. Results: No cytotoxic effect was observed in 0.1 μM and 2 μM gemcitabine alone group. The radiosensitivities were observed in the groups treated with radiation and gemcitabine exposed in different consistencies and times. The SER were 1.35,1.82; 1.55 and 2.16 respectively. The G1 cell cycle phase block was observed in the two consistency groups after exposing to gemcitabine for 24 hours. Dq were rather lower in 2 μM groups especially that exposed for 24 hours. Conclusions: The radiosensitivity was obviously observed in the groups treated with two consistencies of gemcitabine. The effect was more obviously as the consistency and the exposing time increased. The block of cell cycle from G1 to S and the decrease of sublethal damage repair might be contributed to the mechanism. No significant financial relationships to disclose.


Science ◽  
1987 ◽  
Vol 237 (4816) ◽  
pp. 758-762 ◽  
Author(s):  
R. Gomer ◽  
R. Firtel

2002 ◽  
Vol 23 (3) ◽  
pp. 389-401 ◽  
Author(s):  
Alan J. Potter ◽  
Katherine A. Gollahon ◽  
Ben J.A. Palanca ◽  
Mary J. Harbert ◽  
Young M. Choi ◽  
...  

1990 ◽  
Vol 52 (5) ◽  
pp. 986-992
Author(s):  
Takeshi KONO ◽  
Tsukasa TANII ◽  
Masayoshi FURUKAWA ◽  
Nobuyuki MIZUNO ◽  
Shoji TANIGUCHI ◽  
...  

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