Flexible assembly of engineered Tetrahymena ribozymes forming polygonal RNA nanostructures with catalytic ability

ChemBioChem ◽  
2021 ◽  
Author(s):  
Yuki Mori ◽  
Hiroki Oi ◽  
Yuki Suzuki ◽  
Kumi Hidaka ◽  
Hiroshi Sugiyama ◽  
...  
Keyword(s):  
2021 ◽  
Vol 11 (10) ◽  
pp. 4620
Author(s):  
Niki Kousi ◽  
Christos Gkournelos ◽  
Sotiris Aivaliotis ◽  
Konstantinos Lotsaris ◽  
Angelos Christos Bavelos ◽  
...  

This paper discusses a digital twin-based approach for designing and redesigning flexible assembly systems. The digital twin allows modeling the parameters of the production system at different levels including assembly process, production station, and line level. The approach allows dynamically updating the digital twin in runtime, synthesizing data from multiple 2D–3D sensors in order to have up-to-date information about the actual production process. The model integrates both geometrical information and semantics. The model is used in combination with an artificial intelligence logic in order to derive alternative configurations of the production system. The overall approach is discussed with the help of a case study coming from the automotive industry. The case study introduces a production system integrating humans and autonomous mobile dual arm workers.


1995 ◽  
Vol 15 (1) ◽  
pp. 34-34
Author(s):  
Clive Loughlin

Examines the development of a flexible assembly machine, GENASYS [Generic Assembly System] which has been designed to produce a range of components. The machine comprises two manipulator arms, a tool changer and a shuttle system for the pallets on which the assembly operations are performed. Each manipulator is able to select a different tool from a carousel tool change mechanism that can accommodate up to 20 different tools. The machine can easily be programmed for a specific assembly operation and low batch numbers can be produced economically. Timescales for the design and installation of the machine are considerably shorter than for a dedicated assembly line and once installed in a factory new product variants can be accommodated within very short timescales and with low‐retooling costs.


2013 ◽  
Vol 309 ◽  
pp. 55-61 ◽  
Author(s):  
Angela Javorova ◽  
Martina Kusa ◽  
Miriam Matúšová

Operation analysis one of the system scientific disciplines closely related to system engineering. This discipline is part of praxeology. Praxeology deals with the research effectiveness of the procedure methods for all areas of human activity. The aim of this analysis is creating solved situation model and their optimization. Optimization is model extremes finding. There are model parameters values that output achieved minimum or maximum. Competitive environment is the reason for finding optimal solutions in the production process.


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