Personalized evolutionary hypothesis of breast neoplasm based on differential hybridization signals of subtelomeric probes

2015 ◽  
Vol 43 (12) ◽  
pp. 1353-1364
Author(s):  
Parvin Mehdipour ◽  
Firoozeh Javan ◽  
Shahram Savad ◽  
Hamid Karbassian ◽  
Morteza Atri

2021 ◽  
Vol 16 (9) ◽  
pp. 2357-2361
Author(s):  
Abdellatif Bensalah ◽  
Hiba Oudrhiri Benaaddach ◽  
Imane Gouzi ◽  
Meryem Haloua ◽  
Nizar Elbouardi ◽  
...  






Author(s):  
Suzy Ramos Rocha ◽  
Carla Andreia Vilanova Marques

ABSTRACT Objective: To evaluate the functional capacity of women with breast neoplasm undergoing palliative chemotherapy. Method: Cross-sectional study with an analysis of medical records of women with breast cancer undergoing palliative chemotherapy. Results: Out of one hundred evaluated records, most registered 50 years or older (66%), primary education (53%), an income of 1 to 2 minimum wages (87%), invasive ductal carcinoma (95%), positive hormone receptor (64%), and histological grade 1 and 2 (57%). Performance status 0 (49%), 1 (39%), and 2 (12%) were prevalent; these imply, respectively, active patients, with mild and moderate activity restriction. One to four chemotherapy schemes were associated with the inappetence (p =0.00) and weight loss (p =0.001) symptoms. The main complications were neuropathy (31%), medullary compression syndrome (21%), neutropenia (9%), and death (28%). Conclusion: Out of the analyzed women, 88% presented functional capacity 0 and 1, had no or mild restriction of daily activities, were multiply treated, and manifested manageable symptoms. Others, however, presented moderate to severe clinical complications during the treatment, progressing to exclusive palliative care or death.



1994 ◽  
Vol 19 ◽  
pp. S98
Author(s):  
Yumiko Saito ◽  
Kei Maruyama ◽  
Seiichi Kawashima




Author(s):  
Robert Wokler

Both as a scientist and as a writer, Buffon was one of the most highly esteemed figures of the European Enlightenment. In depicting the perpetual flux of the dynamic forces of Nature, he portrayed the varieties of animal and vegetable species as subject to continual change, in contrast with Linnaeus, whose system of classification based on physical descriptions alone appeared timeless. But Buffon’s definition of a species in terms of procreative power excluded the evolutionary hypothesis that any species could become transformed into another. Hybrids, as imperfect copies of their prototypes, were in his scheme ultimately destined to become sterile rather than to generate fresh species. By virtue of the same definition, he judged that the different races of mankind formed family members of a single species, since the mating of humans of all varieties was equally fertile.



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