scholarly journals Patent foramen ovale closure following cryptogenic stroke or transient ischaemic attack: Long-term follow-up of 301 cases

2015 ◽  
Vol 86 (6) ◽  
pp. 1078-1084 ◽  
Author(s):  
Mikaeil Mirzaali ◽  
Maureen Dooley ◽  
Dylan Wynne ◽  
Nina Cooter ◽  
Lorraine Lee ◽  
...  
2008 ◽  
Vol 61 (6) ◽  
pp. 640-643
Author(s):  
Francisco Mazuelos ◽  
José Suárez de Lezo ◽  
Manuel Pan ◽  
Dolores Mesa ◽  
Mónica Delgado ◽  
...  

Author(s):  
Eustaquio M. Onorato ◽  
Vittorio Ambrosini ◽  
Francesco Casilli ◽  
Antonio L. Bartorelli

2015 ◽  
Vol 10 (12) ◽  
pp. 1474-1479 ◽  
Author(s):  
Eric Eeckhout ◽  
Solenne Martin ◽  
Alain Delabays ◽  
Patrik Michel ◽  
Grégoire Girod

2010 ◽  
Vol 76 (1) ◽  
pp. 145-150 ◽  
Author(s):  
Tulio Diaz ◽  
Roberto J. Cubeddu ◽  
Pablo A. Rengifo-Moreno ◽  
Ignacio Cruz-Gonzalez ◽  
Jorge Solis-Martin ◽  
...  

Circulation ◽  
2008 ◽  
Vol 118 (suppl_18) ◽  
Author(s):  
Pablo Rengifo-Moreno ◽  
Ignacio Cruz-Gonzalez ◽  
Roberto J Cubeddu ◽  
Maria Sanchez-Ledezma ◽  
Mingming Ning ◽  
...  

Background: The presence of a patent foramen ovale (PFO) is associated with higher rates of cryptogenic stroke. In patients with hypercoagulable states, the incidence of recurrent cerebral ischemic events may be greatly increased if a PFO is present. Percutaneous PFO closure is an alternative therapeutic approach for patients with both conditions who are not candidates for long-term anticoagulation, or have developed recurrent neurological events despite medical therapy. Methods: Between January 1995 to February 2007, 424 consecutive patients with PFO and cryptogenic stroke underwent percutaneous PFO closure. Of these, we identified 112 (26%) patients with a hypercoagulable disorder. We compared the safety and long-term outcome of percutaneous PFO closure in these two groups of patients. Results: Patients with thrombophilia were older (51.7±13 vs 48.3±14 years, p = 0.025), yet no different regarding baseline demographics or echocardiographic characteristics. Percutaneous PFO closure was successful in all the patients. There were no differences in the type of device used (Amplatzer: 53.6 vs 50%, Cardioseal 39.3 vs 41.7%, Sideris 7.1 vs 8.3%; p= 0.78). At median follow-up of 14.3 months (interquartile range: 6.1–31.4 months) there rate of stroke/TIA was similar for both groups (1.7 vs 1.6%, log rank test p = 0.35). At follow-up echocardiography, the rate of complete PFO closure was greater in the thrombophilic patients (97.3 vs 91.7%, p=0.04). Conclusions: Percutaneous PFO closure is safe and effective in preventing recurrent ischemic cerebral events in patients with thrombophilia.


2011 ◽  
Vol 101 (4) ◽  
pp. 297-303 ◽  
Author(s):  
Dieter Fischer ◽  
Ajmal Gardiwal ◽  
Jonas Haentjes ◽  
Gunnar Klein ◽  
Gerd-Peter Meyer ◽  
...  

Author(s):  
Joel Johnson ◽  
Arber Kodra ◽  
Craig Basman ◽  
S. Jacob Scheinerman ◽  
Nirav Patel ◽  
...  

A patent foramen ovale (PFO) is well known to cause paradoxical embolism and stroke, but a less appreciated and life-threatening complication can occur when combined with severe pulmonary embolism (PE). Acutely elevated right-sided pressures from right ventricular strain due to PE can lead to right-to-left (R-L) shunting through the PFO and exacerbate hypoxia. We report a case of a 50-year-old female patient with massive PE with further desaturation from R-L shunting from a PFO that benefitted from percutaneous closure of the interartrial communication. Our patient recovered without any complications and had excellent long-term follow-up.


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