ChemInform Abstract: BICYCLO(3.3.0)OCTENOL AS AN EFFECTIVE TOOL FOR THE DETERMINATION OF ABSOLUTE CONFIGURATION OF CHIRAL ACIDS. THE ABSOLUTE CONFIGURATION OF ARYL-TERT-BUTYLACETIC ACID

1979 ◽  
Vol 10 (33) ◽  
Author(s):  
H. KURITANI ◽  
S. IMAJO ◽  
K. SHINGU ◽  
M. NAKAGAWA
Keyword(s):  
Absolute Configuration ◽  
Determination Of Absolute Configuration ◽  
The Absolute

(-)-Strempeliopine, stereoselective total synthesis and the determination of absolute configuration

1986 ◽  
Vol 51 (8) ◽  
pp. 1731-1742 ◽  
Author(s):  
Josef Hájíček ◽  
Jan Trojánek
Keyword(s):  
Circular Dichroism ◽  
Total Synthesis ◽  
Absolute Configuration ◽  
Determination Of Absolute Configuration ◽  
Natural Base ◽  
The Absolute ◽  
Circular Dichroïsm

A synthesis of (±)-strempeliopine (II) is described, the key step of which is the stereoselective reductive rearrangement of 18-methylene-1,2-dehydroaspidospermidine (XI). The absolute configuration of the natural (-)-base II was determined as (2S, 7R, 20R, 21R) on the basis of its synthesis from (+)-18-methylenevincadifformine (XVII) the configuration of which was derived from a comparison of circular dichroism properties of bases with a β-anilinoacrylate chromophore. The biogenesis of the alkaloids of the schizozygane type is discussed.

Determination of the absolute configuration of secondary alcohols by modified Horeau's method using HPLC

1989 ◽  
Vol 54 (1) ◽  
pp. 151-159 ◽  
Author(s):  
Aleš Svatoš ◽  
Irena Valterová ◽  
Anna Fábryová ◽  
Jan Vrkoč
Keyword(s):  
Absolute Configuration ◽  
Secondary Alcohols ◽  
Model Compounds ◽  
Defense Substance ◽  
Determination Of Absolute Configuration ◽  
The Absolute

A method for determination of absolute configuration of secondary alcohols, based on a modified Horeau's method, has been developed. The ratio of (1R,2'S)- and (1R,2'R)-N-[1-(1-naphthyl)-ethyl]-2-phenylbutanamides (V and VI, respectively) was determined by HPLC on a straight phase. The method was tested on a series of steroid and terpene model compounds and was used in the determination of absolute configuration of 15-ripperten-3α-ol (XV), the defense substance of Nasutitermes nigriceps termites. The sensibility of the determination is 100 nmol of the alcohol.

The determination of the absolute configuration of vicinal diols

1974 ◽  
Vol 27 (10) ◽  
pp. 2199 ◽  
Author(s):  
DPG Hamon ◽  
RA Massy-Westropp ◽  
T Pipithakul
Keyword(s):  
Absolute Configuration ◽  
Ethyl Lactate ◽  
Determination Of Absolute Configuration ◽  
Vicinal Diols ◽  
The Absolute

Horeau's method for the determination of absolute configuration has been used successfully for the determination of configuration of some cyclic and acyclic vicinal diols. The examples include the four isomeric pinane-2,3-diols and some diols which were prepared from (-)-(S)-ethyl lactate.

Bis(zinc porphyrin) as a CD-sensitive bidentate host molecule: direct determination of absolute configuration of mono-alcohols

2015 ◽  
Vol 51 (55) ◽  
pp. 11068-11071 ◽  
Author(s):  
Satoshi Hayashi ◽  
Miku Yotsukura ◽  
Masahiro Noji ◽  
Toshikatsu Takanami
Keyword(s):  
Absolute Configuration ◽  
Direct Determination ◽  
Host Molecule ◽  
Zinc Porphyrin ◽  
Host System ◽  
System P ◽  
Determination Of Absolute Configuration ◽  
The Absolute ◽  
Circular Dichroic

A facile and direct protocol to determine the absolute configurations of chiral mono-alcohols without analyte derivatization can now be realized using a novel circular dichroic (CD)-sensitive bis(zinc porphyrin) BP1 host system.

scholarly journals Rapid Organocatalytic Chirality Analysis of Amines, Amino Acids, Alcohols, Amino Alcohols and Diols with Achiral Iso(thio)cyanate Probes

2021 ◽  
Author(s):  
Eryn Nelson ◽  
Jeffrey S. S. K. Formen ◽  
Christian Wolf
Keyword(s):  
Amino Acids ◽  
Absolute Configuration ◽  
Rapid Determination ◽  
Amino Alcohols ◽  
Enantioselective Synthesis ◽  
Widespread Occurrence ◽  
Chiral Compounds ◽  
New Methods ◽  
The Absolute

The widespread occurrence and significance of chiral compounds does not only require new methods for their enantioselective synthesis but also efficient tools that allow rapid determination of the absolute configuration,...

scholarly journals Preparative-scale HPLC Resolution of Metallacyclic η3-Allyltricarbonyliron Complexes and Determination of the Absolute Configuration by X-Ray Crystal Structure Analysis

1999 ◽  
Vol 23 (9) ◽  
pp. 578-579
Author(s):  
Rainer Schobert ◽  
Hermann Pfab ◽  
Jutta Böhmer ◽  
Frank Hampel ◽  
Andreas Werner
Keyword(s):  
Crystal Structure ◽  
Silica Gel ◽  
Structure Analysis ◽  
Absolute Configuration ◽  
Crystal Structure Analysis ◽  
Preparative Scale ◽  
X Ray ◽  
The Absolute

Racemates of (η3-allyl)tricarbonyliron lactone complex Fe(CO)3{η1:η3-C(O)XCH2CHCMeCH2} 1a (X = O) and (η3-allyl)tricarbonyliron lactam complex 2a (X = NMe) are resolved on a preparative scale by HPLC on cellulose tris(3,5-dimethylphenyl)carbamate/silica gel RP-8 and the absolute configuration of (-)-2a is determined by X-ray crystal structure analysis.

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