ChemInform Abstract: Palladium-Catalyzed Asymmetric 1,4-Disilylation of α,β-Unsaturated Ketones: Catalytic Asymmetric Synthesis of β-Hydroxy Ketones.

ChemInform ◽  
1988 ◽  
Vol 19 (48) ◽  
Author(s):  
T. HAYASHI ◽  
Y. MATSUMOTO ◽  
Y. ITO
RSC Advances ◽  
2016 ◽  
Vol 6 (88) ◽  
pp. 85058-85062 ◽  
Author(s):  
Mayaka Maeno ◽  
Hiroya Kondo ◽  
Etsuko Tokunaga ◽  
Norio Shibata

Catalytic asymmetric synthesis of fluorinated donepezil, a promising new therapeutic agent for Alzheimer's disease, was achieved.


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