ChemInform Abstract: Novel Small Molecule Epithelial Sodium Channel Inhibitors as Potential Therapeutics in Cystic Fibrosis - a Patent Evaluation

ChemInform ◽  
2014 ◽  
Vol 45 (6) ◽  
pp. no-no
Author(s):  
Matthias Schoenberger ◽  
Mike Althaus
Keyword(s):  
Cystic Fibrosis ◽  
Sodium Channel ◽  
Small Molecule ◽  
Epithelial Sodium Channel ◽  
Patent Evaluation ◽  
Potential Therapeutics

Novel mutation in the epithelial sodium channel causing type I pseudohypoaldosteronism in a patient misdiagnosed with cystic fibrosis

2012 ◽  
Vol 171 (6) ◽  
pp. 997-1000 ◽  
Author(s):  
Francisco Mora-Lopez ◽  
Manuel Bernal-Quiros ◽  
Alfonso M. Lechuga-Sancho ◽  
Jose Luis Lechuga-Campoy ◽  
Nestor Hernandez-Trujillo ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Sodium Channel ◽  
Novel Mutation ◽  
Epithelial Sodium Channel ◽  
Type I

Nonclinical safety assessment of SPX-101, a novel peptide promoter of epithelial sodium channel internalization for the treatment of cystic fibrosis

2017 ◽  
Vol 29 (8) ◽  
pp. 356-365 ◽  
Author(s):  
Matthew P. Walker ◽  
Matt Cowlen ◽  
Dale Christensen ◽  
Mutsumi Miyamoto ◽  
Phillip Barley ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Sodium Channel ◽  
Safety Assessment ◽  
Epithelial Sodium Channel

Mutations in the amiloride-sensitive epithelial sodium channel in patients with cystic fibrosis-like disease

2009 ◽  
Vol 30 (7) ◽  
pp. 1093-1103 ◽  
Author(s):  
Abul Kalam Azad ◽  
Robert Rauh ◽  
François Vermeulen ◽  
Martine Jaspers ◽  
Judit Korbmacher ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Sodium Channel ◽  
Epithelial Sodium Channel
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