Acidity and Glutathione Dual‐Responsive Polydopamine‐Coated Organic‐Inorganic Hybrid Hollow Mesoporous Silica Nanoparticles for Controlled Drug Delivery

ChemMedChem ◽  
2020 ◽  
Vol 15 (20) ◽  
pp. 1940-1946
Author(s):  
Qi Chen ◽  
Yunna Chen ◽  
Wenjing Zhang ◽  
Qianqian Huang ◽  
Mengru Hu ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Mesoporous Silica Nanoparticles ◽  
Controlled Drug Delivery ◽  
Inorganic Hybrid ◽  
Dual Responsive ◽  
Hollow Mesoporous Silica

A soft–hard template approach towards hollow mesoporous silica nanoparticles with rough surfaces for controlled drug delivery and protein adsorption

2015 ◽  
Vol 3 (31) ◽  
pp. 6480-6489 ◽  
Author(s):  
Haijiao Zhang ◽  
Huijuan Xu ◽  
Minghong Wu ◽  
Yufang Zhong ◽  
Donghai Wang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Protein Adsorption ◽  
Rough Surfaces ◽  
Mesoporous Silica Nanoparticles ◽  
Controlled Drug Delivery ◽  
Hard Template ◽  
Hollow Mesoporous Silica

Novel hollow mesoporous silica nanoparticles (HMSNs) with rough surfaces have been successfully prepared using a facile soft–hard template route.

A dual-responsive, hyaluronic acid targeted drug delivery system based on hollow mesoporous silica nanoparticles for cancer therapy

2018 ◽  
Vol 6 (28) ◽  
pp. 4618-4629 ◽  
Author(s):  
Lin Huang ◽  
Jia Liu ◽  
Fan Gao ◽  
Qian Cheng ◽  
Bo Lu ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Cancer Therapy ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Targeted Drug Delivery ◽  
Mesoporous Silica Nanoparticles ◽  
Dual Responsive ◽  
Targeted Drug ◽  
Hollow Mesoporous Silica ◽  
Targeted Drug Delivery System

A novel enzyme and redox dual-responsive targeted drug delivery system based on hollow mesoporous silica nanoparticles was developed for cancer therapy.

Cisplatin and doxorubicin dual-loaded mesoporous silica nanoparticles for controlled drug delivery

RSC Advances ◽  
2016 ◽  
Vol 6 (96) ◽  
pp. 94160-94169 ◽  
Author(s):  
Hanwen Li ◽  
Huijuan Yu ◽  
Caiying Zhu ◽  
Jianhua Hu ◽  
Ming Du ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Mesoporous Silica ◽  
Synergistic Effect ◽  
Silica Nanoparticles ◽  
Therapeutic Efficacy ◽  
Mesoporous Silica Nanoparticles ◽  
Controlled Drug Delivery

Multicomponent therapeutic platforms have been proposed to minimize dosage of each drug and reduce toxicity, leading to achieving a synergistic effect and maximizing therapeutic efficacy.

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