Recent advance in functionalized mesoporous silica nanoparticles with stimuli-responsive polymer brush for controlled drug delivery

2022 ◽  
pp. 1-15
Author(s):  
Latifah Hamad K. Alfhaid
2014 ◽  
Vol 50 (87) ◽  
pp. 13268-13271 ◽  
Author(s):  
Abdul Hakeem ◽  
Ruixue Duan ◽  
Fouzia Zahid ◽  
Chao Dong ◽  
Boya Wang ◽  
...  

Nanoscale ◽  
2018 ◽  
Vol 10 (20) ◽  
pp. 9616-9627 ◽  
Author(s):  
Vijayakameswara Rao N ◽  
Hwa Seung Han ◽  
Hansang Lee ◽  
Van Quy Nguyen ◽  
Sangmin Jeon ◽  
...  

Mesoporous silica nanoparticles (MSNs) with stimuli-responsive gatekeepers have been extensively investigated for controlled drug delivery at the target sites.


2012 ◽  
Vol 2012 ◽  
pp. 1-20 ◽  
Author(s):  
María Vallet-Regí

Mesoporous silica nanoparticles are receiving growing attention by the scientific biomedical community. Among the different types of inorganic nanomaterials, mesoporous silica nanoparticles have emerged as promising multifunctional platforms for nanomedicine. Since their introduction in the drug delivery landscape in 2001, mesoporous materials for drug delivery are receiving growing scientific interest for their potential applications in the biotechnology and nanomedicine fields. The ceramic matrix efficiently protects entrapped guest molecules against enzymatic degradation or denaturation induced by pH and temperature as no swelling or porosity changes take place as a response to variations in the surrounding medium. It is possible to load huge amounts of cargo into the mesopore voids and capping the pore entrances with different nanogates. The application of a stimulus provokes the nanocap removal and triggers the departure of the cargo. This strategy permits the design of stimuli-responsive drug delivery nanodevices.


Sign in / Sign up

Export Citation Format

Share Document