A phase 2 trial of lenvatinib (E7080) in advanced, progressive, radioiodine‐refractory, differentiated thyroid cancer: A clinical outcomes and biomarker assessment

Maria E. Cabanillas; Martin Schlumberger; Barbara Jarzab; Renato G. Martins; Furio Pacini; Bruce Robinson; Judith C. McCaffrey; Manisha H. Shah; Donald L. Bodenner; Duncan Topliss; Corina Andresen; James P. O'Brien; Min Ren; Yasuhiro Funahashi; Roger Allison; Rossella Elisei; Kate Newbold; Lisa F. Licitra; Steven I. Sherman; Douglas W. Ball

doi:10.1002/cncr.29395

A phase 2 trial of lenvatinib (E7080) in advanced, progressive, radioiodine‐refractory, differentiated thyroid cancer: A clinical outcomes and biomarker assessment

Cancer ◽

10.1002/cncr.29395 ◽

2015 ◽

Vol 121 (16) ◽

pp. 2749-2756 ◽

Cited By ~ 90

Author(s):

Maria E. Cabanillas ◽

Martin Schlumberger ◽

Barbara Jarzab ◽

Renato G. Martins ◽

Furio Pacini ◽

...

Keyword(s):

Thyroid Cancer ◽

Clinical Outcomes ◽

Differentiated Thyroid Cancer ◽

Phase 2 ◽

Phase 2 Trial

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Randomized phase 2 trial of cediranib alone or cediranib plus lenalidomide in iodine 131-refractory differentiated thyroid cancer (DTC): A University of Chicago Phase 2 Consortium trial.

Journal of Clinical Oncology ◽

10.1200/jco.2016.34.15_suppl.6013 ◽

2016 ◽

Vol 34 (15_suppl) ◽

pp. 6013-6013 ◽

Cited By ~ 1

Author(s):

Jonas A. De Souza ◽

Theodore Karrison ◽

Bernadette Libao ◽

Francis P. Worden ◽

Monika Krzyzanowska ◽

...

Keyword(s):

Thyroid Cancer ◽

Differentiated Thyroid Cancer ◽

Phase 2 ◽

University Of Chicago ◽

Phase 2 Trial ◽

Iodine 131 ◽

Randomized Phase 2

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Vandetanib in locally advanced or metastatic differentiated thyroid cancer: a randomised, double-blind, phase 2 trial

The Lancet Oncology ◽

10.1016/s1470-2045(12)70335-2 ◽

2012 ◽

Vol 13 (9) ◽

pp. 897-905 ◽

Cited By ~ 212

Author(s):

Sophie Leboulleux ◽

Lars Bastholt ◽

Thomas Krause ◽

Christelle de la Fouchardiere ◽

Jan Tennvall ◽

...

Keyword(s):

Thyroid Cancer ◽

Differentiated Thyroid Cancer ◽

Locally Advanced ◽

Phase 2 ◽

Double Blind ◽

Phase 2 Trial

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Faculty Opinions recommendation of A multiinstitutional phase 2 trial of pazopanib monotherapy in advanced anaplastic thyroid cancer.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.717953610.793459214 ◽

2012 ◽

Author(s):

John H Lazarus

Keyword(s):

Thyroid Cancer ◽

Anaplastic Thyroid Cancer ◽

Phase 2 ◽

Phase 2 Trial

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Analysis of Biomarkers and Association With Clinical Outcomes in Patients With Differentiated Thyroid Cancer: Subanalysis of the Sorafenib Phase III DECISION Trial

Clinical Cancer Research ◽

10.1158/1078-0432.ccr-18-3439 ◽

2019 ◽

Vol 25 (24) ◽

pp. 7370-7380

Author(s):

Marcia S. Brose ◽

Martin Schlumbeger ◽

Michael Jeffers ◽

Christian Kappeler ◽

Gerold Meinhardt ◽

...

Keyword(s):

Thyroid Cancer ◽

Clinical Outcomes ◽

Differentiated Thyroid Cancer ◽

Phase Iii ◽

Decision Trial

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An International Phase 2 Study of Pazopanib in Progressive and Metastatic Thyroglobulin Antibody Negative Radioactive Iodine Refractory Differentiated Thyroid Cancer

Thyroid ◽

10.1089/thy.2019.0269 ◽

2020 ◽

Vol 30 (9) ◽

pp. 1254-1262

Author(s):

Keith C. Bible ◽

Michael E. Menefee ◽

Chia-Chi (Josh) Lin ◽

Michael J. Millward ◽

William J. Maples ◽

...

Keyword(s):

Thyroid Cancer ◽

Differentiated Thyroid Cancer ◽

Radioactive Iodine ◽

Phase 2 ◽

Thyroglobulin Antibody ◽

Phase 2 Study

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A Prognostic Gene Expression Signature in the Molecular Classification of Chemotherapy-naïve Urothelial Cancer is Predictive of Clinical Outcomes from Neoadjuvant Chemotherapy: A Phase 2 Trial of Dose-dense Methotrexate, Vinblastine, Doxorubicin, and Cisplatin with Bevacizumab in Urothelial Cancer

European Urology ◽

10.1016/j.eururo.2015.08.034 ◽

2016 ◽

Vol 69 (5) ◽

pp. 855-862 ◽

Cited By ~ 118

Author(s):

David J. McConkey ◽

Woonyoung Choi ◽

Yu Shen ◽

I.-Ling Lee ◽

Sima Porten ◽

...

Keyword(s):

Gene Expression ◽

Neoadjuvant Chemotherapy ◽

Clinical Outcomes ◽

Urothelial Cancer ◽

Gene Expression Signature ◽

Molecular Classification ◽

Phase 2 ◽

Phase 2 Trial ◽

Dose Dense

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1746P Health-related quality-of-life (HRQoL) analyses from study 211: A phase 2 study in patients (pts) with radioiodine-refractory differentiated thyroid cancer (RR-DTC) treated with 2 starting doses of lenvatinib (LEN)

Annals of Oncology ◽

10.1016/j.annonc.2021.08.892 ◽

2021 ◽

Vol 32 ◽

pp. S1205

Author(s):

M.H. Taylor ◽

S. Leboulleux ◽

Y. Panaseykin ◽

B. Konda ◽

C. de la Fouchardiere ◽

...

Keyword(s):

Quality Of Life ◽

Thyroid Cancer ◽

Differentiated Thyroid Cancer ◽

Phase 2 ◽

Health Related Quality ◽

Phase 2 Study ◽

Related Quality ◽

Health Related

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Faculty Opinions recommendation of Thyroid Lobectomy Is Associated with Excellent Clinical Outcomes in Properly Selected Differentiated Thyroid Cancer Patients with Primary Tumors Greater Than 1 cm.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.725947259.793511547 ◽

2015 ◽

Author(s):

Iain Nixon

Keyword(s):

Thyroid Cancer ◽

Cancer Patients ◽

Clinical Outcomes ◽

Differentiated Thyroid Cancer ◽

Primary Tumors ◽

Thyroid Lobectomy

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Intensity‐modulated radiation therapy and doxorubicin in thyroid cancer: A prospective phase 2 trial

Cancer ◽

10.1002/cncr.33804 ◽

2021 ◽

Author(s):

Paul B. Romesser ◽

Eric J. Sherman ◽

Karissa Whiting ◽

Margaret L. Ho ◽

Ashok R. Shaha ◽

...

Keyword(s):

Radiation Therapy ◽

Thyroid Cancer ◽

Intensity Modulated Radiation Therapy ◽

Phase 2 ◽

Intensity Modulated ◽

Phase 2 Trial ◽

Prospective Phase

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Clinical outcomes of patients with T4 or N1b well-differentiated thyroid cancer after different strategies of adjuvant radioiodine therapy

Scientific Reports ◽

10.1038/s41598-019-42083-3 ◽

2019 ◽

Vol 9 (1) ◽

Cited By ~ 3

Author(s):

Shin Young Jeong ◽

Sang-Woo Lee ◽

Wan Wook Kim ◽

Jin Hyang Jung ◽

Won Kee Lee ◽

...

Keyword(s):

Thyroid Cancer ◽

Clinical Outcomes ◽

Differentiated Thyroid Cancer ◽

Radioiodine Therapy ◽

Well Differentiated

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