scholarly journals Effects of platelet‐rich fibrin on human gingival and periodontal ligament fibroblast proliferation from chronic periodontitis versus periodontally healthy subjects

Author(s):  
Apoorv Goel ◽  
L. Jack Windsor ◽  
Richard L. Gregory ◽  
Steven B. Blanchard ◽  
Yusuke Hamada

2019 ◽  
Vol 24 (2) ◽  
pp. 823-832
Author(s):  
Jennifer Chang ◽  
Steven B. Blanchard ◽  
L. Jack Windsor ◽  
Richard L. Gregory ◽  
Yusuke Hamada


2015 ◽  
Vol 44 (7) ◽  
pp. 1021-1025 ◽  
Author(s):  
Xin Yu Lau ◽  
Haslina Taib ◽  
Zurairah Berahim ◽  
Azlina Ahmad ◽  
Siti Lailatul Akmar Zainuddin


2013 ◽  
Vol 40 (7) ◽  
pp. 661-671 ◽  
Author(s):  
Ahmed R. El-Awady ◽  
Carol A. Lapp ◽  
Ahmed Y. Gamal ◽  
Mohamed M. Sharawy ◽  
Karl H. Wenger ◽  
...  


2021 ◽  
Vol 62 ◽  
pp. 473-476
Author(s):  
Ishandono Dachlan ◽  
Hendy Satrya Kurniawan ◽  
Aditya Wicaksana ◽  
Aditya Rifqi Fauzi ◽  
Firdian Makrufardi ◽  
...  


2021 ◽  
pp. 1-7
Author(s):  
Shivani Sachdeva ◽  
Ameet Mani ◽  
Harish Saluja

Chronic periodontitis is nowadays popularly regarded as Dysbiosis, [1] which causes destruction of tissues rich in collagen like periodontal ligament, alveolar bone and gingival connective tissue. The oral biofilm comprises many periodontal pathogens better regarded as ‘triggers’ in causing chronic periodontitis. Since, not everyone will be affected in the same manner due to periodontal pathogens. Some might not elicit a host response while, the others might have exaggerated response. So, host modulation therapy came into existence to counteract the exaggerated host response. The chemically modified tetracyclines (CMTs) have emerged to inhibit the inflammatory response or to reduce the collagenolytic activity of host. Though a derivative of tetracyclines, it still lacks an antimicrobial action and hence, can be used for periodontitis for longer duration with no adverse effects of gastrointestinal toxicity which parent tetracyclines have.



2010 ◽  
Vol 26 (6) ◽  
pp. 481-483 ◽  
Author(s):  
Beatriz Dulcineia Mendes De Souza ◽  
Eduardo Antunes Bortoluzzi ◽  
Cleonice Da Silveira Teixeira ◽  
Wilson Tadeu Felippe ◽  
Cláudia Maria Oliveira Simões ◽  
...  


Author(s):  
Zeinab Rezaei Esfahrood ◽  
Zahra Yadegari ◽  
Setareh Kazemi Veysari ◽  
Mahdi Kadkhodazadeh


2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Lorena Bortolini Navarro ◽  
Fabiane Barchiki ◽  
Wilson Navarro Junior ◽  
Everdan Carneiro ◽  
Ulisses Xavier da Silva Neto ◽  
...  

AbstractThis study analyzed the efficacy of autologous platelet-rich fibrin (PRF) in maintaining and recovering cell viability of the periodontal ligament (PDL). The PDL cells were isolated from 45 extracted teeth randomly distributed among 6 groups: 5 min, 1 h, 2 h, PRF 30 min, PRF 1 h and PRF 2 h. In the groups 5 min, 1 h and 2 h (n = 5), the teeth were kept dry in extra-alveolar times of 5 min, 1 h and 2 h respectively. The teeth of the groups PRF 30 min, PRF 1 h and PRF 2 h (n = 10) were kept dry at extra-alveolar times of 30 min, 1 and 2 h followed by immersion in PRF for 45 min. PDL cells were isolated by enzymatic digestion with type II collagenase and dispase, counted and analyzed for viability with Trypan blue vital dye in Neubauer chamber. The variables total number of cells and cell viability demonstrated that in the 5 min, 1 h and 2 h groups there was a decrease after the extra-alveolar dry times of 1 and 2 h. In comparison with the total number of cells, group 1 h, considered immediate reimplantation, did not present statistical difference when compared to the groups PRF 30 min, PRF 1 h and 2 h, a result that demonstrates that PRF assists in cell maintenance and recovery. PRF provided increased cell viability in relation to the different dry extra-alveolar times analyzed (p < 0.001). Autologous PRF presented effectiveness in maintaining and recovering PDL cells from extracted teeth and kept dry for up to 2 h.



Sign in / Sign up

Export Citation Format

Share Document