Metastatic hepatocellular carcinoma masquerading as soft tissue sarcoma: A diagnostic challenge

Extraskeletal mesenchymal chondrosarcoma is a rare soft tissue sarcoma arising from soft tissues, mainly of the lower extremities, meninges, and orbits. It usually presents during the second to third decades of life, and has a slight predominance in females. Histologically, it has a typical biphasic pattern comprising small cells and islands of hyaline cartilage. It can pose a diagnostic challenge in small biopsy specimens where 1 of the 2 components can be absent. The prognosis is extremely variable; survival varies depending on the location of the tumor.

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Diffuse type of pigmented villonodular synovitis of knee masquerading as a soft tissue sarcoma

Biomedicine ◽

10.51248/.v40i3.43 ◽

2020 ◽

Vol 40 (3) ◽

pp. 405-408

Author(s):

Bhat Shubha P. ◽

Singh Vartika ◽

Srinivas Teerthanath ◽

Shetty Siddharth M. ◽

Hosapatna Laxminarayana Kishan Prasad ◽

...

Keyword(s):

Soft Tissue ◽

Soft Tissue Sarcoma ◽

Histopathological Examination ◽

Benign Neoplasm ◽

Pigmented Villonodular Synovitis ◽

Villonodular Synovitis ◽

Diffuse Type ◽

Diagnostic Challenge ◽

Radiological Investigation ◽

Pigmented Villonodular

Pigmented villonodular synovitis (PVNS) is a rare benign neoplasm involving the synovial joints and tendon sheaths. It can be classified into localised and diffuse type. The diffuse type of PVNS is larger and very aggressive, clinically mimicking as soft tissue sarcoma. Radiological investigation can aid in knowing the relation of the mass to the joint cavity and invasion of surrounding structures. A biopsy can pose a diagnostic challenge for pathologists. Surgical excision is the treatment of choice. Histopathological examination is necessary for a definite diagnosis. Keywords: Pigmented villonodular synovitis; diffuse; soft tissue sarcoma; histopathology.

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Morphological Examination of a Herpes-type Virus Indigenous for Tree Shrews

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100067790 ◽

1970 ◽

Vol 28 ◽

pp. 160-161

Author(s):

J. P. Brunschwig ◽

R. M. McCombs ◽

R. Mirkovic ◽

M. Benyesh-Melnick

Keyword(s):

Electron Microscopy ◽

Soft Tissue ◽

Chick Embryo ◽

Soft Tissue Sarcoma ◽

Cell Cultures ◽

Tree Shrew ◽

Type Virus ◽

Morphological Examination ◽

Tree Shrews ◽

Embryo Cells

A new virus, established as a member of the herpesvirus group by electron microscopy, was isolated from spontaneously degenerating cell cultures derived from the kidneys and lungs of two normal tree shrews. The virus was found to replicate best in cells derived from the homologous species. The cells used were a tree shrew cell line, T-23, which was derived from a spontaneous soft tissue sarcoma. The virus did not multiply or did so poorly for a limited number of passages in human, monkey, rodent, rabbit or chick embryo cells. In the T-23 cells, the virus behaved as members of the subgroup B of herpesvirus, in that the virus remained primarily cell associated.

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