The role of rapid on site evaluation on touch imprint cytology and brushing during conventional bronchoscopy

2021 ◽  
Author(s):  
Maria Antonietta Botticella ◽  
Simona De Summa ◽  
Luigi Cisternino ◽  
Stefania Tommasi ◽  
Maria Irene Pastena ◽  
...  
Keyword(s):  
Imprint Cytology ◽  
Touch Imprint Cytology ◽  
Site Evaluation

scholarly journals Impact of immediate evaluation of touch imprint cytology from computed tomography guided core needle biopsies of mass lesions: Single institution experience

CytoJournal ◽  
2014 ◽  
Vol 11 ◽  
pp. 15 ◽  
Author(s):  
Mana Moghadamfalahi ◽  
Mirna Podoll ◽  
Amy B. Frey ◽  
Houda Alatassi
Keyword(s):  
Computed Tomography ◽  
Imprint Cytology ◽  
Ct Guided ◽  
Core Needle ◽  
Touch Imprint Cytology ◽  
Effective Manner ◽  
First Pass ◽  
Site Evaluation ◽  
The Impact ◽  
Number Of Passes

Background: Computed tomography (CT) guided core needle biopsy (CT-guided CNB) is a minimally invasive, safe and effective manner of tissue sampling in many organs. The aim of our study is to determine the impact of on-site evaluation of touch imprint cytology (TIC) to minimize the number of passes required to obtain adequate tissue for diagnosis. Design: A retrospective review of all CT-guided CNBs performed during 4 year period, where pathologists were present for on-site TIC evaluation. Each case was evaluated for the number of passes required before TIC was interpreted as adequate for diagnosis. Results: A total of 140 CT-guided CNBs were included in the study (liver, lung, kidney, sacral, paraspinal, omental, splenic and adrenal masses). Of the 140 cases, 109 were diagnosed as malignant, 28 as benign and three insufficient. In 106 cases (75.7%), the biopsies were determined adequate by TIC on the first pass, 19 cases (13%) on the second pass and 7 cases (5%) on the third pass. Only in 5 cases (3.6%), more than three passes were required before diagnostic material was obtained. Three cases (2.14%) were interpreted as inadequate both on TIC and on the final diagnosis. Of the biopsies deemed adequate on the first pass, 71% resulted in either termination of the procedure, or only one additional pass was obtained. In five cases, based on the TIC evaluation, a portion of the sample was sent for either flow cytometric analysis or cytogenetic studies. Conclusions: In the majority of cases, adequate material was obtained in the first pass of CT-guided CNB and once this was obtained, either no additional passes, or one additional pass was performed. This study demonstrates the utility of on-site evaluation in minimizing the number of passes required for obtaining adequate diagnostic material and for proper specimen triage for ancillary studies, which in turn decreases the risk to the patient and costs. However, tumor exhaustion in the tissue as a result of TIC is an important pitfall of the procedure, which occurred in 9 (8.2%) of our malignant cases.

scholarly journals Evaluating intraoperative cytology with histopathology diagnosis and its importance in ovarian tumors

2020 ◽  
Vol 10 (1) ◽  
pp. 1630-1634
Author(s):  
Karishma Malla Vaidya ◽  
Bigya Shrestha ◽  
Runa Jha ◽  
Binit Shrestha ◽  
Aasiya Rajbhandari ◽  
...  
Keyword(s):  
Predictive Value ◽  
Ovarian Neoplasms ◽  
Ovarian Neoplasm ◽  
Imprint Cytology ◽  
Frozen Sections ◽  
Intraoperative Diagnosis ◽  
Touch Imprint Cytology ◽  
Intraoperative Cytology ◽  
Benign Ovarian Neoplasm

Background: Touch/ imprint cytology has been utilized for intraoperative evaluations of tumors to complement frozen sections in order to reach diagnosis prior to histopathology diagnosis. The main aim of this study is to find role of touch imprint in determining histopathology diagnosis of ovarian neoplasm. Materials and Methods: All together one hundred three cases were evaluated using both touch/imprint and histopathology diagnosis. The histopathology diagnoses consisted of Benign (n=85), borderline (n=4), and malignant (n=12). Touch imprint cytology consists of Negative for malignancy (n=90), Positive for malignancy (n=11) and inadequate (n=2). Inadequate smear was excluded from the study. Results: Both touch / imprint cytology were able to diagnose benign and malignant ovarian neoplasm. Out of 103 cases, in cytology showed 89.1% patients were negative and 10.9% patients were positive. Histopathology shows 84.2% of benign ovarian neoplasm, 3.9% borderline neoplasm and 11.9% of malignant. Diagnostic accuracy of touch/ imprint was 99% with sensitivity 100% and specificity was 91.67%. Positive predictive value was 98.89% and negative predictive value was 100%. Conclusion: Touch/ imprint cytology examination is simple, rapid and useful test in evaluation of ovarian neoplasms. It plays very important role in preliminary intraoperative diagnosis of benign and malignant ovarian neoplasms. 

Role of Intra-Operative Touch Imprint Cytology in the Treatment of Breast Cancer

2011 ◽  
Vol 111 (3) ◽  
pp. 130-135 ◽  
Author(s):  
E. Van Eetvelde ◽  
M. Vanhoeij ◽  
G. Verfaillie ◽  
C. Bourgain ◽  
J. Lamote
Keyword(s):  
Breast Cancer ◽  
Imprint Cytology ◽  
Touch Imprint Cytology

scholarly journals Feasibility and accuracy of rapid on-site evaluation of touch imprint cytology during transbronchial biopsy

2020 ◽  
Vol 12 (6) ◽  
pp. 3057-3064
Author(s):  
Kohei Shikano ◽  
Tsukasa Ishiwata ◽  
Fumie Saegusa ◽  
Jiro Terada ◽  
Masashi Sakayori ◽  
...  
Keyword(s):  
Transbronchial Biopsy ◽  
Imprint Cytology ◽  
Touch Imprint Cytology ◽  
Site Evaluation

The current role of touch imprint cytology in sentinel lymph node intra‐operatory examination

2020 ◽  
Vol 26 (3) ◽  
pp. 576-577
Author(s):  
Cristiana Iacuzzo ◽  
Serena Scomersi ◽  
Fabiola Giudici ◽  
Laura Bonadio ◽  
Marina Troian ◽  
...  
Keyword(s):  
Lymph Node ◽  
Sentinel Lymph Node ◽  
Imprint Cytology ◽  
Current Role ◽  
Touch Imprint Cytology

scholarly journals 400 THE ROLE OF ROSE-TIC (TOUCH IMPRINT CYTOLOGY) IN DIAGNOSING GASTROINTESTINAL AND PANCREATICOBILIARY LESIONS DURING ENDOSCOPY

2018 ◽  
Vol 87 (6) ◽  
pp. AB76
Author(s):  
Saeed Ali ◽  
Robert H. Hawes ◽  
Shantel Hebert-Magee ◽  
Udayakumar Navaneethan ◽  
Shyam Varadarajulu ◽  
...  
Keyword(s):  
Imprint Cytology ◽  
Touch Imprint Cytology

scholarly journals The Utility of Rapid On-Site Evaluation during Bronchoscopic Biopsy: A 2-Year Respiratory Endoscopy Central Experience

2019 ◽  
Vol 2019 ◽  
pp. 1-7
Author(s):  
Hansheng Wang ◽  
Na Wei ◽  
Yijun Tang ◽  
Yunyun Wang ◽  
Guoshi Luo ◽  
...  
Keyword(s):  
Lung Cancer ◽  
International Association ◽  
Final Diagnosis ◽  
Needle Aspiration ◽  
European Respiratory Society ◽  
Macroscopic Appearance ◽  
Visible Lesion ◽  
Bronchoscopic Biopsy ◽  
Site Evaluation

Background. Rapid on-site evaluation (ROSE) is commonly used to evaluate the adequacy of biopsy materials in fine-needle aspiration; however, the diagnostic performance of ROSE during fiber optic bronchoscopy (FOB) biopsy under direct vision is rarely reported. Here, we evaluated the role of ROSE during FOB biopsy of visible lesion in trachea or bronchi. Methods. The role of ROSE was prospectively evaluated in consecutive bronchoscopy specimens obtained between January 2016 and January 2018. The agreement and accuracy between ROSE and final histopathological interpretation were assessed. The frequency and possible reasons for discrepancy between ROSE and definitive histopathology results were identified. Histological and cytological classification was performed according to the International Association for the Study of Lung Cancer, the American Thoracic Society, and the European Respiratory Society (IASLC/ATS/ERS) criteria of lung ADCs classification. Results. The study enrolled 651 patients, of which 33 were excluded because of insufficient cells. Final diagnosis of malignancy was achieved in 462 cases (74.8%), whereas 156 cases (25.2%) were nonmalignant. ROSE and pathology were well correlated for the diagnosis of squamous cell carcinoma (SCC) (Kappa = 0.718, p<0.05), adenocarcinoma (AdC) (Kappa = 0.662; p<0.05) and small cell lung cancer (SCLC) (Kappa = 0.955; p<0.05). In 24 cases diagnosed as malignant by ROSE and nonmalignant by pathology, the lesion tissues were surgically excised and re-analyzed, and the 24 cases were finally confirmed as malignant by pathology. Conclusions. ROSE technique allows bronchoscopists to obtain viable and adequate material for the diagnosis of histopathology, and provides them with an onsite preliminary diagnosis especially in cases with inconclusive macroscopic appearance. ROSE and pathology should be used in combination to increase the accuracy of diagnosis.

scholarly journals The Influence of Touch-Imprint Cytology on Further Management for Breast Cancer Patients

2010 ◽  
Vol 8 (7) ◽  
pp. 532
Author(s):  
E. Thomee ◽  
J.E. Rusby ◽  
F.A. MacNeill ◽  
P. Osin
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Imprint Cytology ◽  
Breast Cancer Patients ◽  
Touch Imprint Cytology
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