Sequence determination of phosphorothioated oligonucleotides using MALDI‐TOF mass spectrometry for controlling gene doping in equestrian sports

2021 ◽  
Author(s):  
Teruaki Tozaki ◽  
Ho‐Geun Kwak ◽  
Kotono Nakamura ◽  
Masaki Takasu ◽  
Hideaki Ishii ◽  
...  
2015 ◽  
Vol 12 ◽  
pp. 105-112 ◽  
Author(s):  
Wesley G. Taylor ◽  
Daniel H. Sutherland ◽  
Haixia Zhang ◽  
Dwayne D. Hegedus

2002 ◽  
Vol 215 (1) ◽  
pp. 65-71 ◽  
Author(s):  
Thomas Kislinger ◽  
Andreas Humeny ◽  
Silke Seeber ◽  
Cord-Michael Becker ◽  
Monika Pischetsrieder

Bacteriology ◽  
2020 ◽  
Vol 5 (3) ◽  
pp. 8-13
Author(s):  
A.A. Samoilova ◽  
◽  
I.V. Likhachev ◽  
E.V. Zueva ◽  
E.V. Rogacheva ◽  
...  

Actual microbiological diagnostics of infections caused by Klebsiella spp. should include isolation of the strain, its identification and fastest possible determination of the pathogen susceptibility to antimicrobial agents. We evaluated the prospects of using MALDI-TOF mass spectrometry to determine the susceptibility of Klebsiella spp. strains to antimicrobial agents. According to the results of mass spectrometry Klebsiella spp. strains analysis, we carried out cluster analysis by the UPGMA method based on mass spectra and data on the susceptibility of the studied strains to antimicrobial agents, and then studied the obtained dendrograms. We identified the areas with the highest probability of the location of antibiotic resistance markers by comparing the mass spectra of susceptible and resistant microorganisms at different concentrations of antimicrobial agents. Thus, using MALDI-TOF mass spectrometry, a new direction in assessing the susceptibility of Klebsiella spp. to antimicrobial agents can be formed. Key words: antibiotic resistance, Klebsiella spp., MALDI-TOF mass spectrometry


1999 ◽  
Vol 71 (15) ◽  
pp. 3118-3125 ◽  
Author(s):  
Xian Chen ◽  
Zhengdong Fei ◽  
Lloyd M. Smith ◽  
E. Morton Bradbury ◽  
Vahid Majidi

2002 ◽  
Vol 20 (1) ◽  
pp. 57-64 ◽  
Author(s):  
Monika Werner ◽  
Michael Sych ◽  
Nicole Herbon ◽  
Thomas Illig ◽  
Inke R. König ◽  
...  

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