scholarly journals Regulation of gene expression is associated with tolerance of the Arctic copepod Calanus glacialis to CO 2 ‐acidified sea water

2017 ◽  
Vol 7 (18) ◽  
pp. 7145-7160 ◽  
Author(s):  
Allison Bailey ◽  
Pierre De Wit ◽  
Peter Thor ◽  
Howard I. Browman ◽  
Reidun Bjelland ◽  
...  

Genes ◽  
2020 ◽  
Vol 11 (9) ◽  
pp. 1059
Author(s):  
Alice Shwe ◽  
Tone-Kari Knutsdatter Østbye ◽  
Aleksei Krasnov ◽  
Sigmund Ramberg ◽  
Rune Andreassen

Smoltification and early seawater phase are critical developmental periods with physiological and biochemical changes in Atlantic salmon that facilitates survival in saltwater. MicroRNAs (miRNAs) are known to have important roles in development, but whether any miRNAs are involved in regulation of gene expression during smoltification and the adaption to seawater is largely unknown. Here, small RNA sequencing of materials from head kidney before, during smoltification and post seawater transfer were used to study expression dynamics of miRNAs, while microarray analysis was applied to study mRNA expression dynamics. Comparing all timepoints, 71 miRNAs and 2709 mRNAs were identified as differentially expressed (DE). Hierarchical clustering analysis of the DE miRNAs showed three major clusters with characteristic expression changes. Eighty-one DE mRNAs revealed negatively correlated expression patterns to DE miRNAs in Cluster I and III. Furthermore, 42 of these mRNAs were predicted as DE miRNA targets. Gene enrichment analysis of negatively correlated target genes showed they were enriched in gene ontology groups hormone biosynthesis, stress management, immune response, and ion transport. The results strongly indicate that post-transcriptional regulation of gene expression by miRNAs is important in smoltification and sea water adaption, and this study identifies several putative miRNA-target pairs for further functional studies.



2020 ◽  
Vol 477 (16) ◽  
pp. 3091-3104 ◽  
Author(s):  
Luciana E. Giono ◽  
Alberto R. Kornblihtt

Gene expression is an intricately regulated process that is at the basis of cell differentiation, the maintenance of cell identity and the cellular responses to environmental changes. Alternative splicing, the process by which multiple functionally distinct transcripts are generated from a single gene, is one of the main mechanisms that contribute to expand the coding capacity of genomes and help explain the level of complexity achieved by higher organisms. Eukaryotic transcription is subject to multiple layers of regulation both intrinsic — such as promoter structure — and dynamic, allowing the cell to respond to internal and external signals. Similarly, alternative splicing choices are affected by all of these aspects, mainly through the regulation of transcription elongation, making it a regulatory knob on a par with the regulation of gene expression levels. This review aims to recapitulate some of the history and stepping-stones that led to the paradigms held today about transcription and splicing regulation, with major focus on transcription elongation and its effect on alternative splicing.



2006 ◽  
Vol 114 (S 1) ◽  
Author(s):  
JM Weitzel ◽  
A Wulf ◽  
M Rajkovic ◽  
HJ Seitz


Author(s):  
Yelena I. Polyakova ◽  
Yekaterina I. Novichkova ◽  
Tatiana S. Klyuvitkina ◽  
Elizaveta A. Agafonova ◽  
Irina M. Kryukova

Presented the results of long-term studies of diatoms and aquatic palynomorphs in surface sediments of the Arctic seas and the possibility of their use for the reconstructions of paleocirculation water masses, advection of Atlantic and Bering sea water into the Arctic ocean, changes in the river runoff to the seas, sedimentary processes in the marginal filter of the largest rivers, seasonal sea ice cover and other hydrological parameters.



2011 ◽  
Vol 33 (12) ◽  
pp. 1300-1307
Author(s):  
Xiu-Jun ZHANG ◽  
Mei-Ling LIU ◽  
Meng-Chun JIA


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