Activation of T lymphocytes by lectins and carbohydrate-oxidizing reagents viewed as an immunological recognition of cell-surface modifications seen in the context of “self” major histocompatibility complex antigens

1981 ◽  
Vol 11 (6) ◽  
pp. 475-483 ◽  
Author(s):  
Arthur Kimura ◽  
Bo Ersson
Keyword(s):  
Major Histocompatibility Complex ◽  
T Lymphocytes ◽  
Cell Surface ◽  
Surface Modifications ◽  
Major Histocompatibility ◽  
Major Histocompatibility Complex Antigens ◽  
Histocompatibility Complex ◽  
Immunological Recognition

scholarly journals A MOUSE B-CELL ALLOANTIGEN DETERMINED BY GENE(S) LINKED TO THE MAJOR HISTOCOMPATIBILITY COMPLEX

1973 ◽  
Vol 138 (6) ◽  
pp. 1289-1304 ◽  
Author(s):  
David H. Sachs ◽  
James L. Cone
Keyword(s):  
Major Histocompatibility Complex ◽  
Lymph Node ◽  
T Cell ◽  
B Cells ◽  
Cell Surface ◽  
B Cell ◽  
Surface Antigen ◽  
Major Histocompatibility ◽  
Spleen Cells ◽  
Histocompatibility Complex

Antibodies cytotoxic for only a subpopulation of C57Bl/10 lymph node and spleen cells were detected when rat antiserum against B10.D2 was exhaustively absorbed with B10.A lymphocytes. Antibodies of similar specificity were also detected in B10.A anti-B10.D2 and in B10.A anti-C57Bl/10 alloantisera. Reactions with recombinant strains of mice indicate that the cell-surface antigen(s) responsible for this specificity is determined by gene(s) in or to the left of the Ir-1 region of the major histocompatibility complex. A variety of criteria implicate B cells as the subpopulation of lymphocytes bearing this antigen. In view of these data and the recent report by others of a T-cell alloantigen determined by gene(s) in the major histocompatibility complex, it seems possible that there may be a variety of H-2-linked alloantigens expressed preferentially on subclasses of lymphocytes.

scholarly journals Development of Antidonor Antibody Directed Toward Non–Major Histocompatibility Complex Antigens in Tolerant Animals

2014 ◽  
Vol 98 (5) ◽  
pp. 514-519 ◽  
Author(s):  
Joseph R. Scalea ◽  
Vincenzo Villani ◽  
Bradford C. Gillon ◽  
Joshua Weiner ◽  
Pierre Gianello ◽  
...  
Keyword(s):  
Major Histocompatibility Complex ◽  
Major Histocompatibility ◽  
Major Histocompatibility Complex Antigens ◽  
Histocompatibility Complex
Sign in / Sign up

Export Citation Format

Share Document