Ruthenium(III) Cyclometalates Obtained by Site-Specific Orthometallation and Their Reactivity with Nitric Oxide: Photoinduced Release and Estimation of NO Liberated from the Ruthenium Nitrosyl Complexes

2012 ◽  
Vol 2012 (6) ◽  
pp. 929-938 ◽  
Author(s):  
Kaushik Ghosh ◽  
Sushil Kumar ◽  
Rajan Kumar ◽  
Udai P. Singh
Keyword(s):  
Nitric Oxide ◽  
Site Specific ◽  
Nitrosyl Complexes ◽  
Ruthenium Nitrosyl

Site-specific orthometallation via C–H bond activation and syntheses of ruthenium(iii) organometallics: studies on nitric oxide (NO) reactivity and photorelease of coordinated NO

RSC Advances ◽  
2016 ◽  
Vol 6 (76) ◽  
pp. 72096-72106 ◽  
Author(s):  
Rajan Kumar ◽  
Sushil Kumar ◽  
Manju Bala ◽  
Anand Ratnam ◽  
U. P. Singh ◽  
...  
Keyword(s):  
Crystal Structure ◽  
Nitric Oxide ◽  
Bond Activation ◽  
Site Specific ◽  
Nitrosyl Complexes

σ-Aryl ruthenium(iii) complexes were synthesized by C–H bond activation and organometallic nitrosyl complexes were synthesized and characterized by spectroscopy and crystal structure. Coordinated NO molecule was found to be photolabile.

scholarly journals How does the acidic milieu interfere in the capability of ruthenium nitrosyl complexes to release nitric oxide?

2020 ◽  
Vol 44 (3) ◽  
pp. 773-779
Author(s):  
Renato Pereira Orenha ◽  
Nelson Henrique Morgon ◽  
Julia Contreras-García ◽  
Graziele Cappato Guerra Silva ◽  
Glaucio Régis Nagurniak ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Ruthenium Complexes ◽  
Reduction Reaction ◽  
Nitrosyl Complexes ◽  
Ruthenium Nitrosyl ◽  
Release Mechanisms ◽  
No Release

The nitric oxide has a well-defined role in biology. The ruthenium complexes are model for study NO release mechanisms. The proton increases the capability of these compounds to release NO after reduction reaction or of the light supported reaction.

scholarly journals Nitric oxide (NO) photo-release in a series of ruthenium–nitrosyl complexes: new experimental insights in the search for a comprehensive mechanism

2019 ◽  
Vol 43 (2) ◽  
pp. 755-767 ◽  
Author(s):  
Max Roose ◽  
Marine Tassé ◽  
Pascal G. Lacroix ◽  
Isabelle Malfant
Keyword(s):  
Nitric Oxide ◽  
Nitric Oxide Release ◽  
Nitrosyl Complexes ◽  
Ruthenium Nitrosyl

The mechanism of nitric oxide release is investigated along a series of 1–3 “push–pull” ruthenium nitrosyl complexes.

The Role of π–Donor/Acceptor trans Effect on The NO release in Ruthenium Nitrosyl Complexes: A Computational Insight

2021 ◽  
Author(s):  
Renato Pereira Orenha ◽  
Nelson Morgon ◽  
Graziele Cappato Guerra Silva ◽  
Giovanni Finoto Caramori ◽  
Renato Luis Tame Parreira
Keyword(s):  
Nitric Oxide ◽  
Ruthenium Complexes ◽  
Release Mechanism ◽  
Trans Effect ◽  
Nitrosyl Complexes ◽  
Ruthenium Nitrosyl ◽  
No Release ◽  
Donor Acceptor ◽  
Model Structures

The nitric oxide (NO) molecule is associated to diverse biochemical routes. Ruthenium complexes are commonly used as model structures to control the NO availability. Here, the NO release mechanism in...

Near-IR light-induced photorelease of nitric oxide (NO) on ruthenium nitrosyl complexes: formation, reactivity, and biological effects

2020 ◽  
Vol 49 (31) ◽  
pp. 10772-10785 ◽  
Author(s):  
Bishnubasu Giri ◽  
Taruna Saini ◽  
Sadananda Kumbhakar ◽  
Kalai Selvan K ◽  
Arabinda Muley ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Prostate Cancer Cell ◽  
Biological Effects ◽  
Cancer Cell Line ◽  
Prostate Cancer Cell Line ◽  
Nitrosyl Complexes ◽  
Ruthenium Nitrosyl ◽  
Near Ir ◽  
Line P ◽  
Ir Light

Two new polypyridyl backboned ruthenium nitrosyl complexes have been synthesized which shows efficient NO photorelease and exhibits significant phototoxicity upon irradiation with the visible light in the VCaP prostate cancer cell line.

Blue-to-red light triggered nitric oxide release in cytotoxic/cytostatic ruthenium nitrosyl complexes bearing biomimetic ligands

2021 ◽  
Vol 421 ◽  
pp. 113520
Author(s):  
Elena D. Stolyarova ◽  
Artem A. Mikhailov ◽  
Anton A. Ulantikov ◽  
Julia A. Eremina ◽  
Lyubov S. Klyushova ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Red Light ◽  
Nitric Oxide Release ◽  
Nitrosyl Complexes ◽  
Ruthenium Nitrosyl

Are the Relative Positions (cis–trans) of Ligands Really Able to Modulate the Coordination of NO in Ruthenium Nitrosyl Complexes?

2021 ◽  
Author(s):  
Renato Pereira Orenha ◽  
Graziele Cappato Guerra Silva ◽  
Nelson Morgon ◽  
Giovanni Finoto Caramori ◽  
Renato Luis Tame Parreira
Keyword(s):  
Nitric Oxide ◽  
Biological Processes ◽  
Nitrosyl Complexes ◽  
Ruthenium Nitrosyl ◽  
Model Structures

The nitric oxide is involved in a series of biological processes. Ruthenium tetraammine complexes are model structures to control the NO availability. The influence of ligands is critical to determine...

Photorelease of nitric oxide (NO) on ruthenium nitrosyl complexes with phenyl substituted terpyridines

2017 ◽  
Vol 41 (15) ◽  
pp. 7371-7383 ◽  
Author(s):  
Silvia Amabilino ◽  
Marine Tasse ◽  
Pascal G. Lacroix ◽  
Sonia Mallet-Ladeira ◽  
Véronique Pimienta ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Visible Light ◽  
Nitrosyl Complexes ◽  
Ruthenium Nitrosyl

Transandcisisomers of ruthenium nitrosyl complexes release NO upon irradiation by visible light and give a unique photoproduct.

scholarly journals Multistep Photochemical Reactions of Polypyridine-Based Ruthenium Nitrosyl Complexes in Dimethylsulfoxide

Molecules ◽  
2020 ◽  
Vol 25 (9) ◽  
pp. 2205
Author(s):  
Nataliia Marchenko ◽  
Pascal G. Lacroix ◽  
Valerii Bukhanko ◽  
Marine Tassé ◽  
Carine Duhayon ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Crystal Structures ◽  
Photochemical Reactions ◽  
X Ray ◽  
Nitrosyl Complexes ◽  
Ruthenium Nitrosyl ◽  
Linkage Isomerization ◽  
The Difference

The photorelease of nitric oxide (NO·) has been investigated in dimethylsulfoxide (DMSO) on two compounds of formula [Ru(R-tpy)(bpy)(NO)](PF6)3, in which bpy stands for 2,2′-bipyridine and R-tpy for the 4′-R-2,2′:6′,2″-terpyridine with R = H and MeOPh. It is observed that both complexes are extremely sensitive to traces of water, leading to an equilibrium between [Ru(NO)] and [Ru(NO2)]. The photoproducts of formula [Ru(R-tpy)(bpy)(DMSO)](PF6)2 are further subjected to a photoreaction leading to a reversible linkage isomerization between the stable Ru-DMSO(S) (sulfur linked) and the metastable Ru-DMSO(O) (oxygen linked) species. A set of 4 [Ru(R-tpy)(bpy)(DMSO)]2+ complexes (R = H, MeOPh, BrPh, NO2Ph) is investigated to characterize the ratio and mechanism of the isomerization which is tentatively related to the difference in absorbance between the Ru-DMSO(S) and Ru-DMSO(O) forms. In addition, the X-ray crystal structures of [Ru(tpy)(bpy)(NO)](PF6)3 and [Ru(MeOPh-tpy)(bpy)(DMSO(S))](PF6)2 are presented.

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